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This set of Digestion Multiple Choice Questions & Answers (MCQs) focuses on Digestion Set 3
Q1 | The secretion of the intrinsic factor occurs in :
- Parietal cells of the stomach.
- Chief cells of the stomach.
- Upper duodenum.
- Beta cells of pancreas.
Q2 | So-called hunger pangs :
- Are truly due to smooth muscle spasm of the transverse colon.
- Are associated with esophageal and pyloric contraction that coexist with an empty relaxed stomach.
- Are more common if starvation is associated with hypoglycaemia.
- May occur in a totally vagotomized patient.
Q3 | Basal acid output is increased with which of the following :
- Acidification of the antrum.
- Administration of a H₂ receptor antagonist.
- Vagotomy.
- Alkalinization of the antrum.
Q4 | The cephalic phase of gastric secretion :
- Occurs when food reach the stomch.
- Isnot accompanied by release of GRP.
- Is controlled by the vagi nerves.
- Isnot blocked by injection of atropine.
Q5 | Gastric HCL secretion :
- Is a passive process that occurs in all parts of the stomach.
- Is stimulated by somatostatin,cimetidine & pyrenzepine.
- Is inhibited by histamine,gastrin & acetylcholine.
- plays a significant rule in iron absorption.
Q6 | The gastric peristalsis (True or False) :
- Depends on the basis of electric rhythm (BER).
- Originates at the mid point of the greater curvature and increases in intensity as it sweeps towards the pylorus.
- Is associated with a strong contraction of the antrum ant the end of each wave.
- Always ejects the contents of the gastric antrum into the duodenum.
Q7 | All of the following statements are untrue except:
- Peptic ulcers can be treated by anticholinesterase drugs.
- gastric secretion in response to hypoglycemia is due to gastrin.
- Peptic ulcers tend to heal by removal of the pyloric antrum.
- Vomiting occurs more by smooth muscle than by skeletal muscle activity.
Q8 | Which of the following statement is true?:
- The intrinsic factors is secreted by the parietal cells of the gastric mucosa.
- The gastric juice can’t digest the gastric mucosa because the cell membranes contain a pepsin activator.
- The stomach normally absorbs about 30% of the ingested food.
- The secretion of the gastric juice is associated with increased H⁺ in the blood.
Q9 | Under normal condition, the gastric secretion is:
- Not affected by presence of food in the stomach.
- Stimulated by norepinephrine and inhibited bu curare.
- Increased by distention of the stomach.
- Maximal before food ingestion.
Q10 | About pepsins:
- There are 5 types of exopeptidase enzymes.
- They are secreted by endocytosis as active enzymes.
- They are incapable of autoactivation
- Their optimum pH of action is 1.6- 3.2.
Q11 | The stomach is a poor area for absorption primarily because:
- Most foods are swallowed before ptyalin has a chance to breakdown starch
- pH of the stomach is too high
- The junction between epithelial cells presents wide space for fluid/ion movement
- The stomach lacks villous membranes.
Q12 | Hydrochloric acid secretion:
- Is accomplished by passive diffusion.
- Requires the dissociation of water with subsequent exchange of the hydrogen ion for potassium ion.
- Requires anaerobic metabolism.
- Utilize protein molecules to neutralize OH⁻ remaining in the secretory cells.
Q13 | A 45 years old man is found to have a condition in which the parietal cells of his stomach have been destroyed by an autoimmune mechanism. This condition is often associated with which of the following?:
- Prenicious anaemia.
- Gastric ulcerarion
- Steatorrhea.
- Protein deficiency.
Q14 | It’s believed that in parietal cells of the gastric mucosa (which secrete hydrochloric acid), an active transport system is responsible for the transmembrane passage of:
- Chloride
- Carbon dioxide.
- Bicarbonate.
- Water
Q15 | Pepsin, secreted by the gastric mucosa:
- Continues to act in the neutral medium of the duodenum.
- Is proteolytic on the mucosal surface, in the alkaline medium provided by the mucus secreted by the surface cells of the stomach.
- Is synthesized within the chief cells.
- Doesnot increased in concentration in response to the mental stimuli found in the so’called cephalic phase of gastric digestion
Q16 | Acid secretion in ulcer disease can be reduced by which of the following?
- Blockage of secretin secretion
- Blockage of histamine H₂ receptors.
- Blockage of action of pepsin
- Treatment with antibiotics.
Q17 | The normally innervated stomach (True or False):
- Is stimulated to secrete gastric juice when food is chewed, even if it’s not swallowed
- Can`t secrete HCL when its H₁ histamine receptors are blocked
- the denervated stomach can secrete gastric juice after a meal is ingested.
- Empties more quickly than the denervated stomach.
Q18 | Under the normal conditions, the bulk of gastric secretions are produces:
- Before the food is ingested and while the pleasure of it’s ingestion is anticipated
- While the food stays in the stomach.
- After the food has entered the duodenum.
- During fasting periods.
Q19 | Mucous presents on the surface of the mucosa of the stomach,smal and large intestine is:
- Resistant to enzymes secreted into the lumen of the gastrointestinal tract.
- Alkaline, and thus a poor buffer for alkaline foods.
- A non-amphoteric protein.
- Easily removed from the surface of the stomach by the gastric secretions during the gastric phase of digestion.
Q20 | The enterogastric reflex can be elicted by which of the following?:
- Distension of the duodenum
- Acid chime in the duodenum.
- Hyperosmotic chime in the duodenum.
- All of the above
Q21 | The secretion of gastrin by the pyloric antrum ceases:
- When the stomach is distended by a full meal
- When the gastric mucosa contents have a pH of about 2.0
- If histamine is injected.
- If the vagi are stimulated.
Q22 | Gastric peristalsis:
- Originates in the distal half of the stomach.
- Is characterized by strong contractions of the antrum at the end of the wave.
- Ejects all the contents of the antrum into the duodenum.
- Decreases in intensity as it sweeps toward the pylorus.
Q23 | Which of the following substances is released from the duodenal mucosa in response to acidic gastric juice?:
- Histamine
- Secretin
- Norepinephrine
- Acetyle choline
Q24 | Which of the following hormones is involved in the initiation of the migrating motor comples?:
- Gastrin
- Motilin
- Secretin
- Cholecystokinin
Q25 | The main function of the cardiac sphincter of the stomach is to:
- Prevent the reflux of the gastric contetnt to the esophagus
- Facilitate storage of food on the lower part of the esophagus
- Mix the food particles entering the stomach.
- Control the rate of food entry into the stomach.