Phases of Mitosis

Prophase

Anaphase

Metaphase

Telophase

Metaphase

Chromosomes line up single file at the middle of the cell

Anaphase

Sister chromatids separate

Anaphase

Spindle fibers begin to shorten, pulling chromatids towards opposite ends of the cell

Telophase

A nuclear membrane forms around chromatin

Telophase

Spindle fibers begin to break down

Telophase

Two identical nuclei form

Prophase

Copied DNA condenses into chromosomes

Prophase

The nucleolus disappears, and the nuclear membrane breaks down

Prophase

Spindle fibers begin to form

Cell Cycle

process of cellular reproduction, occurring in three main stages - interphase (growth), mitosis (nuclear division), and cytokinesis (cytoplasm division)

Chromatin

relaxed form of DNA in the nucleus of a cell

Chromosome

DNA-containing structure that carries genetic material from one generation to another

Cytokinesis

third main stage of the cell cycle, during which the cell's cytoplasm divides, creating a new cell

Interphase

first stage of the cell cycle, during which a cell grows, matures, and replicates its DNA

Mitosis

second main stage of the cell cycle during which the cell's replicated DNA divides and two genetically identical diploid daughter cells are produced

Anaphase

third stage of mitosis in which sister chromatids are pulled apart and spindle fibers, along with motor proteins, move the chromosomes to opposite poles of the cell

Centromere

cell structure that joins two sister chromatids

Metaphase

second stage of mitosis in which spindle fibers and motor proteins pull sister chromatids to the cell's equator

Prophase

first stage of mitosis, during which the cell's chromatin condenses into chromosomes

Sister Chromatid

structure that contains identical DNA copies and is formed during DNA replication

Telophase

last stage of mitosis in which nucleoli reappear. Two new nuclear membranes begin to form, but the cell has not yet completely divided.

Apoptosis

programmed cell death

Cancer

uncontrolled growth and division of cells that can be caused by changes in control of the cell cycle and may be caused by environmental factors

Carcinogen

cancer-causing substance

Cell cycle

The stages that take place between the time a eukaryotic cell divides and the time the daughter cells divide. (stages of growth, preparation, and division (Interphase and Mitosis)

Cancer

A malignant growth or tumor caused by abnormal, uncontrolled cell division.

Interphase

Cell grows, performs its normal functions, and prepares for division; consists of G1, S, and G2 phases. (Period of normal growth and maintenance. (3 stages)

G1

In interphase - cell grows rapidly, builds new organelles; also performs regular cell functions

S phase

The "synthesis" phase of the cell cycle; the portion of interphase during which DNA is replicated. (doubles each chromosomes)

G2

Final preparation phase. Cell checks for DNA errors and begins to form centrosomes. (Prepares for Mitosis)

Mitosis

1 diploid parent cell splits into 2 identical diploid daughter cells.

Prophase

Nucleolus has disappeared, and duplicated chromosomes are visible. Centrosomes begin moving apart, and spindle is in process of forming.

Prophase

-the chromosomes coil up and become visible while the nuclear envelope disappears.
-Sister chromatids are present.
A centriole forms at each pole and spindle fibers made of microtubules grow out of it.
-Short microtubules stick out from the centriole in a

Metaphase

Centromeres of duplicated chromosomes are aligned at plate. Fully formed spindle attach to the sister chromatids from opposite poles

Metaphase

Second phase of mitosis, during which the chromosomes line up across the center of the cell

Anaphase

Third phase of mitosis in which sister chromatids are pulled to opposite sides of the cell

Anaphase

-The kinetochores "reel in" or "gobble up" the spindle fibers
-This pulls the sister chromatids apart by splitting their centromere.
The split chromatids are pulled towards opposite poles of the cell

Telophase

The fourth and final stage of mitosis, in which nuclei are forming and cytokinesis has typically begun.

Telophase

-Chromosomes become indistinct
-Daughter cells are forming
-Once the chromatids have reached the opposite sides the spindle fibers disappear
-The chromosomes unravel
-nuclear envelope reappears on the two new nuclei

Cytokinesis

the cytoplasm forms a cleavage furrow at the equator to split the cytoplasm. (in plants a cell plate forms at the equator.)

Chromatids

Bodies of tightly coiled chromatin; visible during cell division. Two chromatids bound at a centromere make a CHROMOSOME.

Spindle fibers

Special strands of microtubules which grow out of the centrioles, connect to chromosomes at the centromeres, and pull them apart during (anaphase) of mitosis.

Chromosomes

DNA that is coiled together and condensed into small packages (like DNA suitcases)
(each has 23 from mom, 23 from dad). Consists of 2 "sister" chromatids bound at a centromere.

Chromatin

unpackaged unwound DNA in the nucleus of a cell

Centromere

holds sister chromatids together.

Metaphase

Prophase

Anaphase

Telophase

Interphase--longest part of cell cycle, when cells grow, develop and duplicate DNA and organelles to prepare for mitosis.

Cell cycle consists of these three phases

Interphase, mitosis and cytokinesis.

Phase of cell cycle that is much longer than the other three.

Interphase--cell growth and development, duplicating DNA and organelles to get ready for division.

Part of cell cycle that is the shortest, after mitosis is complete.

Cytokinesis

cytokinesis

Occurs after telophase (after mitosis is complete) to complete the cell cycle.

cytokinesis.