MB 7.5

How does the cell secrete certain biological molecules?

The cell secretes certain biological molecules by the fusion of vesicles with the plasma membrane; this process is called exocytosis. A transport vesicle that has budded from the Golgi apparatus moves along microtubules of the cytoskeleton to the plasma m

How does endocytosis work?

In endocytosis, the cell takes in biological molecules and particulate matter by forming new vesicles from the plasma membrane. Although the proteins involved in the processes are different, the events of endocytosis look like the reverse of exocytosis.
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How is endocytosis related to cholesterol in humans?

Human cells use receptor-mediated endocytosis to take in cholesterol for membrane synthesis and the synthesis of other steroids. Cholesterol travels in the blood in particles called low-density lipoproteins (LDLs), each a complex of lipids and a protein.

What is atherosclerosis?

It is the buildup of lipid deposits within the walls of blood vessels. This buildup causes the walls of the vessels to bulge inward, thereby narrowing the vessels and impeding blood flow.
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What other functions do vesicles have aside from transporting substances between the cell and its surroundings?

Vesicles not only transport substances between the cell and its surroundings but also provide a mechanism for rejuvenating or remodeling the plasma membrane. Endocytosis and exocytosis occur continually in most eukaryotic cells, yet the amount of plasma m

As the cell grows, its plasma membrane expands. Does this involve endocytosis or exocytosis?

This involves exocytosis. When a transport vesicle fuses with the plasma membrane, the vesicle membrane becomes part of the plasma membrane.

In concept 6.7 you learned that animal cells make an extracellular matrix (ECM). Describe the cellular pathway of synthesis and deposition of an ECM glycoprotein.

The glycoprotein would be synthesized in the ER lumen, move through the Golgi apparatus, and then travel in a vesicle to the plasma membrane, where it would undergo exocytosis and become part of the ECM.

Describe what occurs in phagocytosis.

In phagocytosis, a cell engulfs a particle by wrapping pseudopodia around it and packaging it within a membranous sac called a food vacuole. The particle will be digested after the food vacuole fuses with a lysosome containing hydrolytic enzymes.

Describe what occurs in pinocytosis.

In pinocytosis, the cell "gulps" droplets of extracellular fluid into tiny vesicles. It is not the fluid itself that is needed by the cell, but the molecules dissolved in the droplets. Because any and all included solutes are taken into the cell, pinocyto

Describe what occurs in receptor-mediated endocytosis.

Receptor-mediated endocytosis enables the cell to acquire bulk quantities of specific substances, even though those substances may not be very concentrated in the extracellular fluid. Embedded in the membrane are proteins with specific receptor sites expo