Pharm - Online Quiz Chapter 5

Both statements are false.

The perception of pain is the patient's emotional or psychologic response to pain and varies greatly from individual to individual. The reaction to pain is the physical component to the message of pain as it is carried through the nervous system and is th

At the peripheral nerve endings

The site of action on nonopioid analgesics is:

The first statement is false; the second statement is true

primary action of the nonopioid analgesics is depression of the central nervous system. The inhibition of prostaglandin synthesis reduces the perception of pain

Narcotics

All of the following are classifications of nonopioid analgesics except one. Which one is the exception?

Uricosuric, antipyretic, antiinflammatory, antiplatelet

Which of the following best describes the mechanism of action for the salicylates?

Constipation

All of the following are adverse drug effects of aspirin except one. Which one is the exception?

Gastrointestinal upset

The most common adverse reaction to aspirin is:

Aspirin

Dangerous bleeding can occur when which of the following drugs is combined with warfarin?

Ibuprofen

The drug of choice for inflammatory dental pain is:

Prostaglandins

NSAIDs and aspirin reduce inflammation by inhibiting the synthesis of:

Antiinflammatory

Acetaminophen has all of the following pharmacologic actions except one. Which one is the exception?

Acetaminophen

The drug of choice for fever reduction in children is:

Acetaminophen

Which of the following analgesics would be best for a patient with asthma for relief of a headache or other mild to moderate pain?

Aspirin

Which of the following nonopioid analgesics is recommended for prevention of coronary artery disease and treatment of myocardial infarction?

Caffeine potentiates the analgesic properties of aspirin

Which of the following statements is true regarding the effects of combining caffeine and aspirin?

A decrease in the pain threshold or greater reaction to pain has been said to be associated with emotional stability.

All of the following statements are true about pain except one. Which one is the exception?

a, b, and c only

Nonopioid drugs can be divided into the following groups as analgesics:
A) Salicylates (aspirin-like group)
B) Acetaminophen
C) NSAIDs
D) Steroidal antiinflammatory drugs
E) All of the above
F) a, b, and c only

Salicylates and NSAIDs

Which of the following groups of analgesics are most closely related?

Central nervous system depression

Aspirin has all of the following effects except one. Which one is the exception?

Throbbing or inflammatory

Aspirin is most effective against what type of pain?

Stomach and small intestine

Aspirin is absorbed rapidly from the:

False

An aspirin tablet applied topically to the oral mucosa is an effective way to treat a toothache.

The first part of the statement is true; the second part is false.

Aspirin has a long history of use for relief of mild to moderate pain such as a headache or toothache, and aspirin's worth as an analgesic is well recognized by the lay public.

Hypothalamus

Fever is regulated in which area of the body?

c and d only

Which of the following statements is most correct regarding the use of aspirin as an antipyretic?
A) Aspirin reduces fever by inducing central vasodilation.
B) Aspirin reduces elevated and normal temperatures.
C) Aspirin reduces fever by inducing peripher

All of the above

Aspirin can have adverse drug interactions with which of the following drugs?
A) Probenecid
B) Warfarin
C) Methotrexate
D) Sulfonylureas
E) Antihypertensives
F) All of the above
G) a, b, and d only

The first statement is true; the second statement is false

Buffered aspirins claim to produce fewer gastrointestinal adverse effects. Numerous clinical studies support this claim

NSAIDs

This group of analgesics is believed by many authors to be the most useful in treating dental pain.

Platelet binding, effect on serum uric acid

NSAIDs are similar in their analgesic, antipyretic, and antiinflammatory actions to the salicylates. They differ in their:

Inhibition of the production of cytoprotective mucus in the stomach

What is the mechanism by which the salicylates and the NSAIDs cause gastrointestinal irritation, pain, and bleeding problems?

Central nervous system side effects include sedation, dizziness, confusion, mental depression, headache, vertigo, and convulsions, which are dose dependent.

Which of the following statements is true regarding NSAIDs?

1 day

How long before the procedure should a patient scheduled for oral surgery avoid ibuprofen?

Patients with renal disease

NSAIDs can dangerously decrease renal blood flow and glomerular filtration in what population?

b, c, e, and e only

NSAIDs may increase the drug effects and toxicity when given with these medications:
A) Angiotensin-converting enzyme (ACE) inhibitors
B) Lithium
C) Digoxin
D) Cyclosporine
E) Methotrexate
F) All of the above may have increased drug effects and toxicity
G

Osteoarthritis

NSAIDs are indicated for which of the following conditions?

Phenacetin

All of the following drugs are NSAIDs except one. Which one is the exception?
A) Fenoprofen
B) Ketorolac
C) Naproxen and naproxen sodium
D) Ibuprofen
E) Phenacetin

No real therapeutic advantage over nonselective NSAIDs

The primary advantage of the cyclooxygenase II (COX II)-specific inhibitors is:

a and c only

Acetaminophen has which of the following therapeutic indication?
A) Analgesic
B) Antiinflammatory
C) Antipyretic
D) Antiplatelet
E) All of the above
F) a and c only

One drink a day

What is the maximal safe dose of alcohol that may be ingested with 2 grams of acetaminophen in a normal adult?

b and c only

The risk of nephrotoxicity increases with what pattern of analgesic usage?
A) Occasional
B) Chronic, long term
C) Concurrent use of acetaminophen, aspirin, and NSAIDs
D) b only
E) b and c only