What is acetazolamide
CA inhibitor
Where do CA inhibitors act?
proximal tubule
Where do osmotic diuretics act?
proximal tubule and descending limb
Where do loop diuretics act?
ascending limb
Where do thiazide diuretics act?
distal tubule
Where do K sparing diuretics act?
collecting duct
What is conivaptan?
ADH inhibitor
Which receptors does conivaptan act on?
V1a, v2
What is mannitol?
osmotic diuretic
What is amiloride?
K sparing
What is triamterene?
K sparing
What is spironolactone?
K sparing
What is eplerenone?
K sparing
What is indapamide?
thiazide
What is metolazone?
thiazide
What is chlorthalidone?
thiazide
What is furosemide?
loop
What is bumetanide?
loop
What is ethacrynic acid?
loop
What is acetazolamide's effect on HCO3?
increase in lumen (alkalinize urine)
What is acetazolamide's effect on Na?
inhibit Na/H exchange
What is acetazolamide used for?
alkalosis
What causes type 2 RTA?
acetazolamide
What causes kidney stones?
triamterene, acetazolamide
What causes uric acid retention?
loop, thiazides
What is ototoxic?
loop
What causes low magnesium?
loop, thiazide
What causes hyperglycemia and hyperlipidemia?
thiazides
What causes hypokalemic metabolic alkalosis?
loop, thiazide
What causes hyperchloremic metabolic acidosis?
k sparing
What causes gynecomastia?
spironolactone
What causes hyponatremia?
osmotic, thiazides, loop
What is used to treat cerebral edema?
osmotic
What is used to treat hyperaldosteronism?
K sparing
What is used to treat hypercalciuria?
thiazides
What is used to treat nephrogenic DI?
thiazides
What is used to treat hypercalcemia?
loop
What inhibits Na/k/2Cl cotransport?
loop
What inhibits Na/Cl cotransport?
thiazides
What acts as an aldo receptor block and Na channel inhibitor?
K sparing
What causes decreased ca secretion?
thiazides
What causes increased magnesium secretion?
thiazides, loop
What causes decreased bicarb secretion?
thiazides, loop
What causes decreased urate secretion?
thiazides, loop