Prehospital Emergency Pharmacology Chapter 6

hormones

Chemical messengers, mostly those manufactured by the endocrine glands

Central nervous system

consists of brain and spine

peripheral nervous system

the section of the nervous system lying outside the brain and spinal cord

somatic nervous system

controls voluntary motor functions

autonomic nervous system

contras involuntary automatic functions

sympathetic nervous system

fight or flight" response

parasympathetic nervous system

feed or breed" or "rest and repose

synapse

space between nerve cells

primary neurotransmitters of the autonomic nervous system are

acetylcholine (ACh) and norepinephrine

synapses that use ACh as the neurotransmitter are called

cholinergic synapses

synapses that use norepinephrine as the neurotransmitter are called

adrenergic synapses

The sympathetic nervous system arises from the ______ and ______ region of the spinal cord.

thoracic and lumbar

adrenal medulla

inner part of adrenal gland; secretes epinephrine and norepinephrine

alpha 1 receptors

causes peripheral vasoconstriction, mild bronchodilation, and stimulation of metabolism

alpha 2 receptors

are inhibitory, they serve to prevent overrelease of norepinephrine in the synapse

beta 1 receptors

causes an increase in heart rate, cardiac contractile force, and cardiac automaticity and conduction

beta 2 receptors

causes vasodilation and bronchodilation

Medications that stimulate the sympathetic nervous system are called

sympathomimetics

medications that inhibit the sympathetic nervous system are called

sympatholytics

nicotinic n receptors

Ganglionic transmission of SNS and PNS, promotes release of epi from medulla

nicotinic m receptors

located at neuromuscular junction of skeletal muscle, causes skeletal muscle contraction

muscarinic receptors

found in many organs throughout the body primarily responsible for promoting the parasympathetic response