Lecture #8 Muscle Tissue

Three types of muscle tissue

skeletal, cardiac, smooth

Excitability

ability to receive and respond to stimuli

Contractability

muscle fibers that are stimulated by nerves contract which causes movement

Elasticity

returns to its original resting length after being stretched or contracted

Extensability

ability to be stretched

cardiac muscle location

myocardium of the heart

cardiac muscle cell shape

branched and "Y" shaped

Cardiac muscle # of nuclei

uni- or binucleated

Is cardiac muscle striated?

yes it's striated

Cardiac muscle control

involuntary

Cardiac muscle special features

intercalated discs, autorhythmic

Smooth muscle location

mostly in the walls of visceral organs (think digestive system)

Smooth muscle cell shape

Fusiform

Smooth muscle number of nuclei

uninucleated

Smooth muscle striations?

no striations

Smooth muscle control

involuntary

Smooth muscle special features

Fatigue-resistant

skeletal muscle location

connected to bones

skeletal muscle cell shape

fiber-like (long and cylindrical)

skeletal muscle number of nuclei

multinucleated

skeletal muscle striations?

yes it striated

Skeletal muscle control

voluntary

Skeletal muscle special features

innervated at the NMJ, Vascular

Skeletal muscle functions

movement, maintain posture, temperature regulation, Storage and movement of materials, support abdominal organs, joint stabilization

deep fascia

wraps muscle groups

epimysium

surrounds entire muscle

Perimysium

wraps around a fascicle

Endomysium

wraps muscle cells

tendon

Connects muscle to bone

Muscle-Tendon Connection

collagen fibers of endomysium, perimysium, and epimysium are continuous with tendons

flat tendons

aponeuroses

origin

less movable attachment site

insertion

more movable attachment site

muscle is made up of

fascicles

fascicles are made up of

muscle fibers/ myofibers

Myofibers are made of

myofibrils

Sarcolemma

muscle cell membrane that sends neural pulse through out muscle

Sarcomere

contractile unit of a muscle fiber

Z disc

Separates the sarcomeres from each other

thick filaments

composed of myosin
Grabs a hold of actin during contraction

muscle excitability

Neuron activates Sarcolemma at the neuromuscular junction

thin filaments

actin, troponin, tropomyosin

What happens at the NMJ

Action potential goes through the synaptic end bulb
impulse travels to sarcolemma through synaptic cleft

sarcoplasmic reticulum

Organelle of the muscle fiber that stores calcium.

t tubule

sends pulse to sarcoplasmic reticulum

triad

a T tubule and two terminal cisterns

Terminal cisternae of sarcoplasmic reticulum

Structures within skeletal muscle cells that serve as reservoirs of calcium ions

muscle contraction steps

Calcium is released from the terminal cisternae
calcium attaches to the troponin
actin is now exposed to the myosin
myosin pulls on the actin

muscle relaxtion

calcium is reobsorbed
ATP is required

Rigor Mortis

Death is a process
Tissues continue to live after the brain, heart and lungs fail
A few hours after death, ATP runs out
- myosin cannot detach from actin
- calcium cannot be reabsorbed
-causes continual muscle contraction
After 15-24 hours, myofibrils beg

Tetanus

caused by clostridium tetani
excessive muscle contraction

Botulism

caused by clostridium botulinum
muscular paralysis
botox