Human Anatomy & Physiology: 18.5 Pacemaker Cells Flashcards

pacemaker cells contract

FALSE

the sponteneously produced action is called

autorhythmic

where are pacemaker cells located?

throughout heart along special conduction pathways

what spreads the depolarizing current to cardiac muscle cells

gap junctions

pacemaker cells have an unstable resting membrane potential

TRUE

the resting membrane potential of pacemaker cells is what?

-60 mV

pacemaker cells close K+ channels and open Na+
slowly to let sodium in

TRUE

the cell become slowly depolarized by the Na+ voltage
channels opening

TRUE

the threshold of pacemaker cells is what?

-40mV

at the threshold what voltage gated channel opens?

Ca2+

for pacemakers to repolarize what is opened?

K+ voltage gated channels

conduction pathways run throughout the myocardium

TRUE

what initiates the heart beat

the SA node

SA node

sinoatrial node

where are the SA nodes?

small mass of pacemaker cells in right atrial wall; inferior to the
superior vena cava

how many impulses does the SA node generate a minute

75

The SA node generates a faster impulse than any other heart cell

TRUE

the SA node is the true pacemaker of the heart

TRUE

what does the Bachmann's bundle connect?

the right and left atria

the bachmann's bundle keeps both atria at synch

TRUE

depolarization of the SA node causes what to happen?

atria to contract at the same time

there are gap junctions between atrial and ventricular myocardium

FALSE

what does the internodal pathways connect?

SA node to AV node

where is the AV node located

in the interatrial septum, near tricuspid

What does the AV node do?

delays depolarization

AV node

atrioventricular node

how many impulses does the AV node generate per minute?

50

the AV node cannot run the heart if the SA is damages

FALSE

the atrioventricular bundle connects what

AV node to ventricles

bundle of His

atrioventricular bundle

what is the only electrical connection between the atria and the ventricles?

atrioventricular bundle

atrioventricular bundle splits into right and left bundle branches

TRUE

atrioventricular bundle does not continue on to form Purkinje fibers

FALSE

purkinje fibers

depolarize the contractile cells of ventricles

subendocardial conducting network

purkinje fibers

purkinje fibers innervate papillary muscles

TRUE

depolarization of pacemaker cells cause depolarilzation of cardiac
muscles cells

TRUE

what is the resting membrane potential in contractile cells

-90 mV

in resting membrane potential in contractile cells what channel is
always open?

K+

what is the resting membrane potential for skeletal muscle?

-90 mV

during depolarization of contractile cells what is opened?

voltage gates fast Na+ channels, Na rapidly flow into cell

sarcolemma depolarizes to +30mV

TRUE

at +30mV what opens in contractile cells?

voltaged gates slow Ca2+ channels

during repolarization of contractile cells what is opened?

voltage gated K+ channels and K+ leaves the cell

absolute refractory period

time when cell cannot depolarize again

the absolute refractory period is longer in cardiac muscle than
skeletal muscle

TRUE

the absolute refractory period prevents tetanic contractions such as
cramps, spasms, and tremors

TRUE

hypercalcemia

too much calcium

what does hypercalcemia cause?

prolonged and spastic heart contractions

hypocalcemia

low calcium levels

hypocalcemia reduces what?

the force of each heartbeat

hyperkalemia

high potassium levels

what does hyperkalemia do?

speeds up membrane repolarization disrupting heart rhythm

hypernatremia

blood Na+ levels are too high

what does hypernatremia prevent

the entry of calcium into myocardium

arrhythmia is a heart defect

TRUE

arrhythmia

uncoordinated atrial and ventricular contraction

two types of arrhythmia

PAT and V-tac

PAT

paroxysmal atrial tachycardia; burst of atrial contractions

V-tac

ventricular tachycardia; rapid uncoordinated ventricular contractions

fibrillation

rapid and irregular contractions of cardiac muscles

what can treat fibrillation

defibrillator

what can lead to fibrillation

tachycardia

defibrillation does what?

restart entire electrical systems

ectopic focus

inappropriate region of heart controls rhythm

where can ectopic focuses appear

atria or ventricles

what are ectopic focuses caused by

ischemic damage to conduction pathways stimulants
fever

what can ectopic focuses lead to

arrhythmia and fibrillation

a heart block is damage to what structure in the heart ?

AV node or AV bundle

first degree heart block

depolarization is delayed for too long

second degree heart block

only some of the impulses are transmitted

third degree heart block

no action potential pass to the ventricles

third degree heart block aka

complete heart block

asystole

period when heart fails to contract

asystole is when there are electrical signals from cardiac muscles

FALSE

flatline

asystole