Innate immunity:Immunological memory: yes or no
no
Adaptive immunity:immunological memory: yes or no
yes
Innate immunity:nonspecific/rapid: yes or no
yes
Adaptive immunity: Ag specific/slower: yes or no
yes
Innate immune system causes1.2.3.
1. graft injury during reperfusion2. inflammation/scarring3. primes/enhances activity of adaptive immune system
Adaptive immune system causes:1. 2. 3.
1. graft recognition2. rejection3. tolerance
cytokines are chemical ____
messengers
Inflammatory cytokine examples
TNF alphaIL-1, 6, 17chemochines
proliferation, differentiation of cells cytokine examples
TGF-betaIL-2, 4, 5, 10, `1INF-gamma
only ____ cells express cytokine receptor components
activated
IL2 receptor affinity:gamma + beta
intermediate
IL2 receptor affinity:alpha only
low
IL2 receptor affinity:gamma, beta, + alpha
high
IL-2 receptor aka...
CD25
B lymphocytes go through ___ to become mature B lymphocytes
bone marrow
T lymphocytes go through ___ to become mature T lymphocytes
thymus
Helper T cells: phenotypic markers CD___
CD3 aka TCRCD4
cytotoxic T cells: phenotypic markers CD____
CD3 aka TCR CD8