Which collagen is most prevalent in basement membrane?
Type IV
Which of the following diseases are NOT characteristic of AIDS? A. lymphoma; B. Tuberculosis; C. Herpes simplex virus; D. Kaposi's Sarcoma; E. None of the above
None of the above
What is used to characterize an AIDS infection?
Decreased CD4 count, increased viral load
Where are B cells derived?
(fetal) bone marrow
What is essential in the creation of vaccinations?
Plasma cells, B lymphocytes
Atopy is
A local chronic allergy
What are characteristics of a type I hypersensitivity reaction?
Hives, itching, and redness
What is NOT true of MHC?
Most similar in first cousins
What is another word for urticaria?
Hives
Which is a characteristic of Sjorgen syndrome?
Keratocongivitis and xerostomia
Angioedema is
Localized swelling in response to an allergic reaction
What is the result of vasodilation?
Redness and heat
Which of the following diseases involves the thyroid?
Graves disease
What is not characteristic of chronic inflammation? Neutrophils, Multinucleated giant cells, macrophages, lymphocytes
Neutrophils
Foreign body giant cells are also referred to as Langhans cells. True or false?
False
Which of the following is not in acute inflammation? Leukocytosis, Fibrosis, vasodilation
Fibrosis
Which cell is the hallmark cell in acute inflammation?
Neutrophils
What is true about anaphylaxis?
Bronchoconstriction, can be treated with anti-histamines
Ischemia can cause: (ribosomal detachment, increase in aerobic glycolysis, cell shrinkage)
Ribosomal detachment
What is the most important antigen-presenting cell?
Dendritic cell
Which of the following is not a cause of atrophy? Increased functional demand, aging, hypoxia, ischemia, interruption of hormonal/endocrine stimulation
Increased functional demand
Edema is the infiltration of only inflammatory cells into the site of infection. True or false?
False
What determines if organ hyperplasia can occur
Capacity for renewal/regeneration
Which of the mediators of acute inflammation activate pain receptors?
Bradykinin
Hypertension can lead to
Compensatory hypertrophy of myocardial cells
Plasma cells are
Terminally differentiated B cells
Which chemokine influences acute inflammation?
Serotonin
Healing by primary intention is
A clean incision with approximated ends, little granulation tissue forms and less scar tissue results
What is true of Barrett's disease?
Changes in squamous to glandular cells in esophagus due to increased gastric reflux
Which of the following is a labile cell?
Gastrointestinal tract cell
Integrins are important for?
Leukocyte margination
What is the direct movement of cells due to a chemical signal?
Chemotaxis
Which hypersensitivity is characterized by antibody-mediated and alteration of cell function?
II
What are the cytokines released by macrophages that mediate acute inflammation?
IL-1 and TNF-alpha
Which of the following is a predisposition to candidiasis?
Sjogren's syndrome, HIV, T-cell deficiency (All of the above)
Stem cells and cancer _____ telomerase activity. The most important assault for cell gaining is _____.
Have; oxidative stress
Melkersson-Rosenthal disease is characterized by:
Labial swelling, facial palsy, and fissured tongue
Which of the following is incorrect?
There is inflammation with apoptosis
What happens with necrosis?
Degradative enzymes released; chromatin condensation, fragmentation, and degradation; initial cell swelling; ions accumulate inside and calcification
What is angiogenesis?
Formation of new blood vessels
What is released by mast cells that causes increased vascular permeability and vasodilation?
Histamine
What is hydropic swelling caused by?
Dysfunction of sodium-potassium pump
Corticosteroids are
Used to treat RA; predispose you to immune suppression
Too much of a good thing is not a good thing is relevant to which of the following diseases: Sjogren syndrome, lupus, candidiasis
...
The immune system...
Has a discriminative invader response, distinguishes self and non-self, and has memory (all of the above)
Change from one cell type to another is known as
Metaplasia
Waiting until an infection is resolved before performing tissue repair is considered
Healing by tertiary intention