chap. 13 disease of red blood cells

anemia

deficiency in erythrocytes or hemoglobin

asplastic

failure of blood cell production in the bone marrow

hemolytic anemia

reduction in the red cells due ti excessive destruction

pernicious anemia

lack of mature erythrocytes caused by inability to absorb vitamin B 12 into the body.

sickle cell anemia

hereditary condition characterized by abnormal sickle shape of erythrocytes and by hemolysis

thalassemia

inherited defect in the ability to produce hemoglobin, usually seen in persons of mediterranean

hemochromatosis

excess iron deposits throughout the body.

polycythemia vera

general increase in red blood cells (erythremia)

hemophilia

excessive bleeding caused by hereditary lack of blood clotting factors necessary for blood clotting

purpura

multiple pinpoint hemorrhages and accumulation of blood under the skin.

leukemia

increase in cancerous white blood cells (leukocytes)

granulocytosis

abnormal increase in granulocytes in the blood.

mononucleosis

infectious disease marked by increased numbers of leukocytes and enlarge cervical lymph nodes.

multiple myeloma

malignant neoplasm of bone marrow.

antiglobulin test

test for the presence of antibodies that coat and damage erythrocytes.

bleeding time

time required for blood to stop flowing from a tiny puncture wound.

coagulation time

time required for venous blood to clot in a test tube

complete blood count (CBC)

determination of numbers of blood cells, hemoglobin concentration, hematocrit, and red cell values- MCH, MCV, MCHC

erythrocyte sedimentation rate (ESR)

speed at which erythrocytes settle out of plasma.

hematocrit (Hct)

percentage of erythrocytes in a volume of blood

hemoglobin test (H, Hg, Hgb, HGB)

total amount of hemoglobin in a sample of peripheral blood.

platelet count

number of platelets per cubic millimeter or microliter of blood.

prothrombin time (PT)

test of the ability of blood clot

red blood cell count (RBC)

number of erythrocytes per cubic millimeter and microliter of blood

red blood cell morphology

microscopic examination of a stained blood smear to determine the shape of individual red cells.

white blood cells count (WBC)

number of leukocytes per cubic millimeter or microliter of blood.

white blood cell differential [count]

percentages of different types of leukocytes in the blood.

apheresis

separation of blood into component parts and removal of a select portion from the blood.

blood transfusion

whole blood or cells are taken from a donor and infused into a patient.

bone marrow biopsy

microscopic examination of a core of bone marrow removed with a needle.

hematopoietic stem cell transplantation

peripheral stem cells from a compatible donor are administered to a recipient.