Ch.4 Cell Physiology

Hydration

-Level of fluid in the body

Animals take in water by:

-Eating moist foods and drinking fluids-Metabolic water

Animal lose water

-Insensible-Sweating, vocalizing, urinating, defecating-Vomiting, diarrhea, excessive sweating, hemorrhaging, and elevated body temperature

Insensible Water Loss

-Diffused passively away from the skin-Vaporized during respiration

Intracellular

-Inside cell-2/3 of total body water

Extracellular

-Outside cell-1/3 of total body water

Interstitial

-Between cells-3/4 of extracellular

Intravascular

-In vessels-1/4 of extracellular

Highest Intracellular Concentration

-Potassium-Magnesium-Hydrogen phosphate-Sulfate

Highest Extracellular Concentration

-Sodium-Bicarbonate-Chloride

Osmolality

-Measurement of solute concentration in fluid

Isotonic

-Osmolality comparable to that of blood

Fluid outside cell has:

-Same concentration of dissolved substances as in the cytoplasm.

Hypotonic

-Osmolality is less than that of blood-Fluid outside the cell has lower concentration of solutes then in the cytoplasm-water flows into the cell and cause it to swell and possibly to break

Hypertonic

-Osmolality is greater than that of blood-Fluid outside of cell is more concentrated than in the cytoplasm-Water shifts into the extracellular space, causing the cell to shrink and become shriveled

Edema

-Abnormal/excess accumulation of fluid in tissue-Ex. Pulmonary and Cutaneous

Pulmonary Edema

-Excess fluid in lung tissue

Subcutaneous Edema

-Fluid under the skin

Crystalloid

-Composed of water rich with electrolytes-Solutes are small

Colloid

-Heavy molecules suspended in isotonic crystalloid-Solutes too large to cross vascular wall

Fluid Therapy phases

-Resuscitation-Replacement-Maintenance

Resuscitation

-Increase intravascular volume (BP)

Replacement

-Correct dehydration

-Maintenance

-To mitigate decreased H2O intake and/or ongoing loses

Passive process

-Do not require energy

Active processes

-Do require energy

Diffusion

-Kinetic movement of molecules from higher to lower concentration

Facilitated Diffusion

-Selective carrier proteins assist in movement of molecules from higher to lower concentration

Osmosis

-Passive movement of water through a semipermeable membrane from dilute solution to a more concentrate one

Osmotic Pressure

-Force that affects water movement from one side to the other

Oncotic Pressure

-The Contribution of blood colloids to osmotic pressure (albumin in particular)

Ascites

-Fluid leaks into abdominal space

Filtration

-Dependent on pressure gradient and membrane permeability

Hydrostatic pressure

-Force that pushes liquid