Alcohol
inappropriate sexual or aggressive behaviors; impaired judgment; slurred speech; emotional lability; incoordination; unsteady gait; involuntary, rhythmic movement of the eyes; impaired attention or memory; stupor; coma.
Amphetamines/Cocaine
euphoria; anxiety; hyperactivity; grandiosity; confusion; anger; paranoia; auditory hallucinations; tachycardia; elevated or lowered blood pressure; dilated pupils; perspiration or chills; nausea or vomiting; weight loss; psychomotor agitation; muscular weakness; confusion; seizures.
Caffeine
restlessness; nervousness; excitement; insomnia; flushed face; diuresis; gastrointestinal disturbance; muscle twitches; rambling flow of thought and speech; tachycardia or arrhythmia; periods of inexhaustibility; psychomotor agitation.
Hallucinogens
perceptual changes; anxiety; depression; ideas of reference; paranoid ideation; pupillary dilation; tachycardia; sweating; palpitations; blurred vision; tremors; incoordination.
Cannabis
impaired motor coordination; euphoria; anxiety; sensation of slowed time; impaired judgment; social withdrawal; conjunctival injection (redness of the eyes); increased appetite; dry mouth; tachycardia.
Opioids
initial euphoria followed by apathy or dysphoria; pupillary constriction; drowsiness or coma; slurred speech; impairment in attention and memory.