LOM Chapter 13

Leukemia

Blood Cancer

Lymphoma

Lymph node cancer

Sarcoma

epithial cell cancer

Melenoma

cancer of the melanin producing cells

carcinoma

involves supportive tissue such as bone and muscle

sickle cell anemia

A hereditary condition characterized by abnormal sickle shape of erythrocytes and by hemolysis

aplastic anemia

failure of blood cell production due to aplasia of bone marrow cells

Thalassemia

inherited defect in the ability to produce hemoglobin

Eosinophil

white blood cell with reddish granules; numbers increase in allergic reactions

fibrin

protein threads that form the basis of a clot

electrophoresis

method of separating out plasma proteins by electrical charge

antigens

foreign material that invades the body

bilirubin

pigment produced from hemoglobin when red blood cells are destroyed

hematopoietic stem cell

an undifferentiated blood cell is called a

heparin

anticoagulant found in the blood

poikilocytosis

a disorder of red blood cell morphology

neutropenia

deficiency in numbers of white blood cells

erythroblast

immature red blood cell

myeloid

derived from bone marrow

hemolysis

breakdown of reipient's red blood cells when incompatible bloods are mixed

iron deficiency anemia

sideropenia occurs causing deficient production of hemoglobin

hemolytic anemia

reduction in red blood cells due to excessive cell destruction

aplastic anemia

failure of blood cell production due to absence of formation of cells in the bone marrow

thalassemia

inherited defect in ability to produce hemoglobin

pernicious anemia

lack of mature red blood cells due to inability to absorb vitamin b12 into the body

hemochromatosis

excessive deposits of iron throughout the body

acute lymphocytic leukemia

symptoms a pallor, shortness of breath, infection, bleeding gums, predominance of immature and abnormally functioning leukocytes, and low numbers of mature neurophils in a young child may indicate a likely diagnosis of

hemophilia

excessice bleeding caused by congenital lack foactor vIII or IX

coagulation time

venous blood is clotted in a test tube

hematocrit

sample of blood is spun in a test tube so that red blood cells fall to the bottom and percentage of RBC's is taken

red blood cell morphology

blood smear is examined to determine the shape or form of cells

white blood cell differntial

leukocytes are stained and counted under a microscope to see numbers of mature and immature forms

erythrocyte sedimentation rate

venous blood is collected; anticoagulant added and the distance cells fall in a period of time is determined

albumin

blood preotein that maintains the proper proportion and concentration of water in blood

immunoglobulins

IgM, IgC, IgA, IgD, IgE

relapse

symptoms of disease return

palliative

relieving symptoms, but not curing disease

erythrocyte

red blood cell

monocyte

white blood cell; phagtocyte and precursor of a macrophage

platelet

thrombocyte

lymphocyte

bone marrow cell; gives rise to many types of blood cells

hematopoietic stem cell

leukocyte formed in lymph tissue; produces antibodies

eosinophils

leukocyte with dense, reddish granules; associated with allergic reactions

neutrophil

leukocyte formed in bone marrow and having neutral-staining granules

basophil

leukocyte whose granules have an affinity for basic stain; releases histamine and heparin

plasma

liquid protion of blood

erythropoietin

hormone secreted by the kidney to stimulate erythrocyte production in bone marrow

globulins

proteins in plasma; cen be seperated into alpha, beta, and gamma types

albumin

plasma protein that maintains the proper amount of water in the blood

antibody

proteins made by lymphocytes in response to antigens in the blood

poikilocytosis

irregularity in shape

erythrocytopenia

deficiency in numbers

hychroma

reduction of hemoglobin

microcytosis

increase in numbers of small cells

polycythemia vera

erythremia

macrocytosis

increase in numbers of large cells

erythropoiesis

formation of red cells

hemolysis

destruction of red cells

palliative

relieving, but not curing

pancytopenia

deficiency of all blood cells

eosinophilia

increase in numbers of granulocytes; seen in allergic condition

purpura

multiple pinpoint hemorrhages; blood accumulates under the skin

apheresis

speration of blood into its components

remission

symptoms of disease disappear

thrombocytosis

abnormal condition of blood clotting

differentiation

change in structure and function of a cell as it matures; specialization

megakaryocyte

platelet precursor found in bone marrow

albumin

protein found in blood; maintains the proper amount of water in blood

sideropenia

deficiency of iron

myeloblast

immature bone marrow cell that developes into a white blood cell

neutropenia

deficiency of a type of white blood cell

fibrin

protein threads that form the basis of a blood clot

hemoglobin

blood protein found in red blood cells

serum

plasma minus clotting proteins and cells

poikilocytosis

condition of cells of unequal size

anisocytosis

condition of cells of unequal size

anticoagulation

a substance that prevents clotting of blood

hemolysis

brerakdown of recipient's red blood cells when incompatible bloods are mixed

plateletpheresis

serparation of clotting cells from the rest of the blood(using centrifuge)

erythropoiesis

formation of red blood cells

White Blood Cells diferentiation

determines the numbers of different types of leukocytes

Red blood cells morphology

determines the shape or form of erythrocytes

hematocrit

percentage of erythrocytes in a volume of blood

dyscrasia

any abnormal or pathological condition of the blood

purpura

multiple pinpoint hemorrhages; thrombocytopenia

hemophilia

excess bleeding caused by the lack of factor VIII or IX

acute lymphocytic leukemia

lymphoblasts preodominate on the blood; most often seen in children

multiple myeloma

malignant tumor of the bone marrow

coagulation time

time required for venous blood to clot in a test tube

bone marrow biopsy

small amount of bone marrow is aspirated and examined under a microscope

palliative

relieving pain but not curing an illness

pernicious anemia

lack of mature erythrocytes owing to inability to absorb vitamin B12

hemoglobin test

total amount of blood protein is measured in a sample of blood

erythrocyte sedimentation rate

speed at which red blood cells settle out of plasma

myeloma

malignant neoplasm of bone marrow

erythropoeisis

condition of forming red blood cells

billirubin

pigment produced from hemoglobin when red blood cells are destroyed

fibronogen

plasma protein that convert into fibrin in the clotting process

platlet

clotting cell

poikilocytosis

irregularity in shape of red blood cells

leukopheresis

seperating white blood cells from the blood

heparin

anticoagulant found in blood and tissue cells

electropheresis

method of seperating serum

bilirubin

orange-yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells die

colony-stimulating factor

protein that stimulates the growth and proliferation of white blood cells

albumin

protein in blood; maintains the proper amount of water in the blood

bosophil

granulocytic white blood cell; granules turn blue with basic stain

coagulation

blood clotting

antigen

substance that stimulates the production of antibodies

differentiation

change in structure and function of a cell as it matures;specialization

antibody

protein produced by lymphocytes in response to antigens

electrophoresis

method of seperating serum proteins by electrical charge

eosinophil

granulocytic white blood cell associated with allergic reactions; granules turn red with acidic stain

coagul/o

clotting

cyt/o

cell

erythr/o

red

hem/o

blood

kary/o

nucleus

leuk/o

white

myel/o

bone marrow

morph/o

shape, form

neutr/o

neutral

sider/o

iron

phag/o

eat, swallowing

thromb/o

clot

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removal

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immature cell

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abnormal condition of cells

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blood condition

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protein

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pertaining to destruction

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deficiency

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eat, swallow

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carry, transmission

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formation

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stop, control

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derived from

anti-

against

hypo-

below, deficient

macro-

large

mega-

large

micro-

small

mono-

one

pan-

all

poly-

many