Ch01: The Microbial World and You

Microbes

Also called microorganisms; are minute living things that individually are usually too small to be seen with the unaided eye. The group includes bacteria, fungi (yeasts and molds), protozoa, microscopic algae, and viruses.

Pathogenic

Disease producing

Scientific Nomenclature

Established in 1735 by Carolus Linnaeus; assigns each organism 2 names -- the GENUS (plura: genera) is the first name and is always capitalized; the specific epithet (species name) follows and is not capitalized. Both names are underlined or italicized.
S

Bacteria

Relatively simple, single-celled (unicellular) organisms. Because their genetic material is not enclosed in a special nuclear membrane, bacterial cells are called prokaryotes (prenucleus). Prokaryotes include both the bacteria and the archaea. Shapes incl

Archaea

Like bacteria, archaea consist of prokaryotic cells, but if they have cell walls, the walls lack peptidoglycan; they are often found in extreme environments and are divided into 3 groups: methanogens, extreme halophiles, and extreme thermophiles.

Methanogens, Halophiles, and Thermophiles

Methanogens produce methane as a waste product from respiration. The extreme halophiles live in extremely salty environments; extreme thermophiles

Fungi

Eukaryotes, organisms whose cells have a distinct nucleus containing the cell's genetic material (DNA), surrounded by a special envelope called the nuclear membrane.

Protozoa

are unicellular, eukaryotic microbes. Protozoa move by pseudopods, flagella, or cilia.

Algae

are photosynthetic eukaryotes with a wide variety of shapes and both sexual and asexual reproductive forms. Algae of interest to microbiologists are usually unicellular.

Viruses

are so small that most can be seen only with an electron microscope, and they are acellular. Structurally very simple, a virus particle contains a core made of only one type of nucleic acid, either DNA or RNA.

List the 3 domains

1) Bacteria
2) Fungi
3) Plants
*In 1978, Carl Woese devised a system of classification based on the cellular organization of organisms. It groups all organisms in three domains above.

1) Bacteria

cells walls contain a protein-carbohydrate complex called peptidoglycan

2) Fungi

Unicellular yeasts, multicellular molds, and mushrooms

3) Eukarya

Includes the following:
* Protists (slime molds, protozoa, and algae)
* Fungi (unicellular yeasts, multicellular molds, and mushrooms)
* Plants (includes mosses, ferns, conifers, and flowering plants)
* Animals (includes sponges, worms, insects, and verte

Robert Hooke

In 1665, after observing a thin slice of cork, an Englishman, Robert Hooke, reported that life's smallest structural units were "little boxes," or "cells,". This discovery marked the beginning of cell theory (all living things are composed of cells).

Anton van Leeuwenhoek

Dutch merchant and mateur scientist Anton van Leeuwenhoek was probably the firs to actually observe live microorganisms through the magnifying lenses of more than 400 microscopes he constructed. Did detailed drawings of "animalcules" in rainwater, in his

Spontaneous Generation

Until second half of the nineteenth century, many scientists and philosophers believed that some forms of life could arise spontaneously from nonliving matter.
Francesco Redi (1668) did maggot experiment to disprove but people were not convinced (need fre

Biogenesis

Coined by German scientist Rudolf Virchow who challenged idea of spontaneous generation. Claim that living cells an arise only from preexisting living cells. Arguments about spontaneous generation continued until 1861, when the issue was resolved by the F

Louis Pasteur

French scientist who disproved the theory of spontaneous generation with his S-shaped curved beef broth experiment. He showed that microorganisms can be present in nonliving matter and that life can be destroyed by heat, forming the basis of ASEPTIC TECHN

Fermentation

Microorganisms called yeasts convert the sugars to alcohol in the absence of air. Discovered by Louis Pasteur, this process is used to make wine and beer. Souring and spoilage are caused by different microorganisms called bacteria. In the presence of air,

Pasteurization

Process invented by Pasteur to reduce spoilage and kill potentially harmful bacteria in milk as well as in some alcoholic drinks.

Germ Theory of Disease

Theory that microorganisms might cause disease.

Chemotherapy

Using chemical substances to treat diseases

Paul Ehrlich

German physician who came up with "salvarsan", an arsenic derivative effective against syphilis.

Alexander Fleming

Scottish physician and bacteriologist almost tossed out some culture plates contaminated by mold, but noticed a round spot where bacterial growth was inhibited. Mold was identified as Penicillium chrysogenum. In 1928, he named teh mold's active inhibitor

Bacteriology

The study of badteria which began with van Leeuwenhock's first examination of tooth scrapings.

Mycology

The study of fungi, which includes medical, agricultural, and ecological branches.

Parasitology

The study of protozoa and parasitic worms.

Genomics

Study of all of an organism's genes

Immunology

The study of immunity, dating back in Western culture to Jenner's first vaccine in 1796.

Virology

The study of viruses.

Paul Berg

Late 1960s; showed that fragments of human or animal DNA (genes) that code for important proteins can be attached to bacterial DNA. The resulting hybrid was teh first example of recombinant DNA. When recombinant DNA is inserted into bacteria (and other mi

George W. Beadle & Edward L. Tatum

Demonstrated relationship btw genes adn enzymes.

James Watson & Francis Crick

Proposed model for teh structure and replication of DNA.

Beijerinck & Winogradsky

Works help to open up field of microbial ecology, teh study of teh relationship btw microorganisms and their environment.