Ch.1 and 2

Cells are

The basic structural and functional units of living organism

Nucleoids are found in

Prokaryotes

Nucleoids differ from the nucleus in two ways

Shape and Nucleoids have no membrane

Organelles found only in animal cells

lysosomes and centrioles

Lysosome

Only acidic organelle, function is waste disposal and recycling

Organelle only found in plant cells

Chloroplast and cell wall

Prokaryote size

1 micrometer

Eukaryote size

10 micrometers

Prokaryotes

- unicellular, few organelles, has 30s+50s Ribosomes

Eukaryotes

unicellular or multicellular organisms, Numerous organelles, has 40s+60s Ribosomes

Eukaryotes are

10-100X larger than prokaryotic cells

Cell wall function

-Cell maintenance, protects from injury, extra protection, made of peptidoglycan in bacteria and is covered in lipid bilayer in plant cells, cellulose, and protein

plasma membrane

Cell maintenance, in all cells, made of lipid bilayers,
Provides cell boundary, Maintains pH and composition of cytosol, Helps delivery of larger molecules, provides surface for membrane-bound enzymes

Cytoplasm

In all cell types, Cell maintenance, anything inside contains 70% H2O, 20% proteins, 10% carbs and lipids,
Maintains a pH near 7.4, main vessel for many reactions

Name the four classes of small biomolecules

amino acids, nucleotides, monosaccharides (sugars), fatty acids

In what larger biomolecules the four classes of biomolecules found?

Monomers: Polymers:
Amino Acids--- Proteins
Nucleotides---Nucleic Acids
Monosaccharides(sugars)---Polysaccharides
Fatty acids---Lipids

5 major ions in biomolecules

Na+, K+, Ca+2, Mg+2, Cl-

List four basic principles that are central to our current understanding of living organisms.

-Living organisms are cellular
-Living organisms are information based
-Organisms adapt and evolve
-Living organisms are complex yet simple in constituents

Lysosome

Cellular components removal and recycling

Mitochondria

ATP production

RER

Glycoprotein/secretory protein synthesis

SER

Lipid Synthesis

Peroxisome

Removal of ROS

Ribosomes

Cytosolic protein synthesis

Golgi

Processing of Carbohydrates, sorting proteins according to their destination

Purposes of chemical reactions occurring in cells

-Breakdown to produce chemical energy
-synthesis needed for maintenance, growth and development, and reproduction
-removal of wastes products (major wastes: CO2, NH3, H2O)

Auto energy

C8H18 + Excess O2----> 4CO2 + 9H2O + energy

Aerobic energy

C6H12O6 + Excess O2 -----> 6CO2 + 6H2O + Energy

Hydrolysis- First most common reactions in cells

Polymer + H2O ----> Monomers

Dehydration- Second most common reaction in cells

Monomers ----> Polymer + H2O

List pieces of evidence that support the endosymbiotic relationship between
eukaryotic cells and mitochondria

Cell size: Mitochondria & Prokaryotic are 1-10 micromole
Cell division: ---------------------- Binary
Ribosomes ---------------- 50s + 30s
DNA shape------------- circular
Transcript----------- intronless
mRNA----------- Polycistronic (No poly A)

Hydration

adds H2O--- H2O is a reactant

Isomerization

intramolecular rearrangement

Redox

follow 2H; gain 2H is reduction, loose 2H is oxidation

Endosymbiosis

Two dissimilar organisms are living together in an intimate relationship, where each exploits the other for its own benefit

The endosymbiosis hypothesis proposes that

Large anaerobic eukaryotic cells (host) ingested small aerobic prokaryotes (bacteria) a long time ago. In exchange for protection and constant energy supply, the bacteria provided its host with energy generated by a process known as aerobic respiration.
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Alkene

C=C

Alcohol

C-OH

Thiol

-SH

Amine

NH2

Aldehyde

H-C=O

carboxylic acid

COOH

Ketone

RCOR

Ether

Alcohol + Alcohol Carboxyl
C-O-C

Ester

acid + alcohol
-CO-O-

Amides

Acid + Amine
-CO-NH-

Phosphoesters

-C-O-P
Alcohol + Phosphate

Phospohoannhydrides

P-O-P
Phosphate + Phosphate

Addition (Hydration)

Water is reactant and added across C=C, one product

Elimination/Dehydration

Water is a product

oxidation-reduction reaction

adds or removes 2H

Cytoskeleton

Eukaryotic cells-

Eukaryotes

Plant and animal cells- have nucleus

Prokaryotes

Bacteria and Archaea- contain Nucleoid

Replication

Copying process by which a cell duplicates its DNA

Transcription

synthesis of an RNA molecule from a DNA template

Splicing

Removal of nonessential segments from RNA copy

Essential DNA segment

Exon ()

Nonessential DNA segment

Intron -----