Anatomy and Physiology Bone Physiology

Axial Skeleton

Part of the skeleton that consists of the bone of the head, trunk, vertebrae

Appendicular Skeleton

The portion of the skeleton consisting of the bones or cartilage that support the appendages; legs, arms, and pelvis

Condyle

A rounded process that usually articulates with other bone

Crest

A narrow ridge-like projection

Epicondyle

A projection situated above a condyle

Facet

A small, nearly flat surface

Fissue

A cleft or groove

Fontanel

A soft spot in the skull where membranes cover the space between bones

Foramen

An opening through a bone that usually serves as a passageway for blood vessels, nerves, or ligaments

Fossa

A relatively deep pit or depression

Fovea

A tiny pit or depression

Head

An enlargement on the end of a bone

Linea

A narrow ridge

Meatus

A tube-like passageway within a bone

Process

A prominent projection on a bone

Ramus

A branch or similar extension

Sinus

A cavity within a bone

Spine

A thorn-like projection

Suture

An interlocking union between bones

Trochanter

A relatively large process

Tubercle

A small, knob-like process

Tuberosity

A knob-like process usually larger than a tubercle

Bone

�Bone forms around vessels
�Vascular and dynamic
�Allows for repair and remodeling
�Protect soft organs
�Provide framework
�Allow muscle attachment
�Storage of minerals
�Hemostasis

Hyaline Cartilage

�Most common type of cartilage
�Found on the end of many bones and joints, in soft part of the nose, and supporting rings of the respiratory passages
�Important for development and growth of most bones
�Endochondral bones (most of the bones in the skeleto

Elastic Cartilage

�More flexible than hyaline cartilage because the matrix contains many elastic fibers
�Provides framework for the external ears and parts of the larynx

Fibrocartilage

�Very tough tissue contains many collagenous fibers
�Shock absorber for structures that are subjected to pressure
�Forms pads (intervertebral discs) between individual bones of the spinal column

Long Bones

�Have long longitudinal axises
�Example: Ulna, Fibula, Femur, Humerus

Short Bones

�Are somewhat cube-like with their lengths and widths roughly equal
�Example: Wrist and ankle bones

Flat Bones

�Plate-like structures with broad surfaces, such as ribs, scapulae and some bones in the skull

Irregular Bones

�Have a variety of shapes and are usually connected to several other bones
�Example: Vertebrae and many facial bones

Sesamoid Bones

�Usually small and nodular are are embedded within tendons adjacent to joint where the tendons are compressed

Endochondral

�"Inside cartilage"
�Most bones in the skeleton are endochondral bones
�Develop from hyaline cartilage shaped like future bony structures, grow rapidly

Interstitial Growth

Cartilage growths in length

Appositional Growth

Cartilage grows in thickness

Ossification

�Cartilage cells enlarge and their lacunae grow, surrounding; soon the cartilage cells die and degenerate
�As the cartilage decomposes, a periosteum forms from connective tissue that encircles the developing structure
�Blood vessel and undifferentiated co

Osteoblasts

�A bone-forming cell
�Migrate in periosteum and deposit bone - but become trapped and decrease metabolism, maintaining existing bone (osteocyte)

Osteoclasts

�A cell that erodes bone
�Osteoblast engulfed by a monocyte (white blood cell) 'eaten' by phagocytosis
�Secretes HCl

Osteocytes

�A mature bone cell

Osteon

Or a Haversian system, consists of concentric layers, or lamellae, of compact bone tissue that surround a central canal, the Haversian canal which contains the bone's blood supply

Intramembranous Ossification

�Flat bones of the skull
�During development (osteogenesis), membrane like layers of unspecialized, or primitive connective tissue appear at the sites of future bones
�Dense networks of blood vessels supply these connective tissue layers
�Primitive cells

Epiphyseal Plate

Hyaline cartilage plate in the metaphysis at each end of a long bone

Epiphyseal Line

Cartilage that remains between the di and epiphysis of a bone

Cartilaginous Cell Layer

�Within long bone epiphysis that grows, occur in 4 layers
1. Closest to the epiphysis is composed of resting cells that do not actively participate in growth
2. The second layer contains rows of many young cells undergoing mitosis
3. Rows of older cells w

Blood Calcium

�Negative feedback
�If blood Ca+2 DECREASES then INCREASE parathormone
�If blood Ca+2 INCREASES then DECREASE calcitonin