LOM Ch. 5 & 6, Digestive

Four functions of the gastrointestinal tract

Ingestion, digestion, absorption, and elimination

Deglutition

swallowing
the epiglottis of the pharynx covers the trachea so food cannot enter and become logged in the windpipe

papillae

small raised areas on the tongue, contain taste buds that are sensitive to the chemical nature of foods and allow discrimination of different tastes such as food moves across the tongue

Tonsils

masses of lymphatic tissue in depressions of the mucous membranes
lie on both side of the oropharynx
they are filters to protect the body from the invasion of microorganisms and produce lymphocytes

Name the 8 types of teeth

central incisor
lateral incisor
canine teeth
1st premolar
2nd premolar
1st molar
2nd molar
3rd molar (wisdom teeth)

Labial surface

labi/o = lip
for incisor and canine teeth, is nearest the lips

Buccal surface

bucc/o = cheek
for premolar and molar teeth, lies adjacent to the cheek

Facial surface

Faci/o = face
Contains Labial and Buccal surface

Lingual Surface

On the side of the tooth directly opposite the facial surface

Mesial Surface

lies nearer to the medial line

Distal surface

lies farther from the medial line

Occlusal surface

applies to premolar and molar surfaces
Where tooth comes into contact with corresponding tooth in the opposing arch.

Incisal edge

Both incisors and canines have this shape edge

A tooth consists of 5 parts

crown
root
enamel
dentin
pulp

Crown

above gum line

root

lies within the bony tooth socket

enamel

Outer most protective layer of the crown
it is dense, hard, and white
Hardest substance in the body

Dentin

the main substance of the tooth, lies beneath the enamel and extends throughout the crown

Cementum

covers, protects, and supports dentin in the root

Periodontal membrane

surrounds the cementum and holds the tooth in place in the tooth socket

Pulp

lies underneath the dentin
soft and delicate tissue that fills the center of the tooth
blood vessels, nerve endings, CT, and lymphatic vessels are withing the pump canal (root canal)

Root canal

necessary when disease or abces occurs in pulp canal
dentist opens the tooth from above and cleans the canal of infected tissue, nerves, and blood vessels
The canal is then disinfected and filled with material to prevent the entrance of microorganisms tha

Salivary glands

surround and empty into the oral cavity
They are exocrine glands that produce saliva, which lubricates the mouth
3 types: Parotid gland, submandibular gland, and sublingual gland
All 3 are on both sides of the mouth, narrow ducts carry saliva into the ora

saliva

lubricates the mouth and contains important digestive enzymes as well as healing growth factors such as CYTOKINES
released from the Parotid gland, submandibular gland, and sublingual gland

Pharynx

(throat)
muscular tube, about 5 inches long, luned with a mucous membrane
serves as a passageway both for air (nose -> trachea) and for food (mouth -> esophagus)

Esophagus

9-10" long muscular tube extending from the pharynx to the stomach
Uses PERISTALSIS to propel a BOLUS down toward the stomach

Peristalsis

involuntary, progressive, rhythmic contraction of muscles of esophageal wall and other gastrointestinal organs to propel a bolus

Stomach (3 parts)

fundus, body, and antrum
Contains 2 sphincters: Lower esophageal Spincter & Pyloric sphincter
Lined with RUGAE (folds in the mucous membrane of stomach) which contain pepsin and HCl
the stomach controls passage of foods into the first part of the small in

Lower esophageal Sphincter

relaxes and contracts to move food from the esophagus into the stomach

Pyloric Sphincter

allows food to leave the stomach when it is ready

Rugae

folds in the mucous membrane lining the stomach
contain digestive glands that produce pepsin (begin digest protein) and HCl

Small intestine (small Bowel)

20 feet
duodenum (1') , jejunum (8'), ileum (11')
Millions of tiny VILLI line the walls. Tiny capillaries in villi absorb the digested nutrients into the bloodstream and lymph vessels

Duodenum

1 foot long
receives bolus from stomach, bile from liver & gallbladder, and pancreatic juices from pancreas

large Intestine

3 main parts: cecum, colon, and rectum
It receives the fluid waste products of digestion (material unable to be absorbed into the bloodstream) and stores them until they can be released from the body

Cecum

a pouch on the right side of the body that connects ileum at the ileocecal valve (sphincter)
contains the appendix

Colon

5 feet in length
Ascending colon, hepatic flexure, transverse colon, splenic flexure, decending colon, sigmoid colon, rectum, anus

Liver

Located URQ
continually releases bile
maintains normal glucose. It removes excess glucose from bloodstream and stores it as glycogen. When the body needs glucose, the liver uses GLYCOGENOLYSIS to break down stored glycogen into glucose. The liver also use

Bile

made by the liver, orange-black, greenish thick fluid
contains choesterol, bile acids, and several bile pigments including bilirubin.
Bile emulsifies fats, which breaks apart large fat globules, creating more surface area so that enzymes from the pancreas

Liver -> Storage of bile -> duodenum

When bile is released from the liver it travels thru the HEPATIC DUCT into the CYSTIC DUCT -> gallbladder where it is stored
In response to food in the stomach and duodenum, the gallbladder contracts to release bile into the cystic duct -> COMMON BILE DUC

Bilirubin

a pigment in bile that is produced from the breakdown of hemoglobin during RBC destruction
It travels in the bloodstream to the lover, where it is conjugated into a water soluble form and added to bile --> duodenum
Bacteria in the colon degrade bilirubin

Jaundice (hyperbilirubinemia)

If the bile duct is blocked or the liver is damaged and unable to excrete bilirubin into bile, bilirubin remains in the bloodstream causing jaundice
Yellow discoloration of the skin, whites of the eyes, and mucous membranes

Portal vein

brings blood to the liver from the intestines
Digested foods pass into the portal vein directly after being absorbed into the capillaries of the small intestine, thus giving the liver the first chance to use the nutrients

pancreas

both an exocrine and endocrine organ
as an exocrine organ, it produces enzymes to digest starch (amylase), fat (lipase), and protein (protease). These pass form the pancreatic duct to the common bile duct into the duodenum.
as an endocrine organ (secretin

an/o

anus
perianal

append/o

appendix
appendectomy

appendic/o

appendix
appendicitis

bucc/o

cheek
buccal mucosa

cec/o

cecum
cecal

celi/o

belly, abdomen
celiac

cheil/o

lip
cheilosis

cholecyst/o

gallbladder
cholecystectomy

choledoch/o

common bile duct
Choledochotomy

col/o

colon, large intestine
colostomy

colon/o

colon
colonic, colonoscopy

dent/i

tooth
dentibuccal

duoden/o

duodenum
duodenal

enter/o

intestines, usually small intestine
enterocolitis, enteroenterostomy, mesentery, parenteral

esophag/o

esophagus

faci/o

face
facial

gastr/o

stomach

gingiv/o

gums
gingivitis

gloss/o

tongue

hepat/o

liver

ile/o

ileum
ileocecal sphincter

jejun/o

jejunum
choledochojejunostomy

labi/o

lip

lapar/o

abdomen
laparoscopy

lingu/o

tongue

mandibul/o

lower jaw, mandible

odont/o

tooth

or/o

mouth

palat/o

palate
palatoplasty

pancreat/o

pancreas

peritone/o

peritoneum
peritonitis (no e)

pharyng/o

throat

proct/o

anus and rectum
proctologist

pylor/o

pyloric sphincter
pyloroplasty

rect/o

rectum
rectocele

sialaden/o

salivary gland
sialadenitis

sigmoid/o

sigmoid colon

stomat/o

mouth

uvul/o

uvula
uvulectomy

amyl/o

starch

bil/i

gall, bile
biliary

bilirubin/o

bilirubin
hyperbilirubinemia

chol/e

gall, bile
cholelithiasis

chlorhydro/o

hydrochoric acid
achlorhydria

gluc/o glyc/o

sugar

glycogen/o

glycogen

lip/o

fat, lipid

lith/o

stone
lithogenesis

prote/o

protein
protease

sial/o

saliva, salivary
sialolith

steat/o

fat
steatorrhea

-ase

enzyme

-chezia

defecation, elimination of wastes
hematochezia

-iasis

abnormal condition
choledocholithiasis

-prandial

meal
postprandial

anorexia

lack of appetite
-sign of malignancy or liver disease
Anorexia nervousa is loss of apetite associated with emotional problems. Eating disorder.

ascities

abnormal accumulation of fluid in the abdomen
-occurs when fluid passes from the bloodstream and collects in the peritoneal cavity.
-Can be a sign of of neoplasm or inflammatory disorders in the abdomen, venous hypertension caused by liver disease, or hea

borborygmus (plural: borborygmi)

Rumbling or gurgling noise produced by the movement of gas, fluid, or both in the gastrointestinal tract
- a sign of hyperactive intestinal peristalsis, often are present during gastoenteritis or diarrhea

constipation

difficulty in passing stool
Occurs when peristalsis is slow and stools become dry/hard.
*diet of fruit, vegetables, and water is helpful. As well as laxatives and cathartics

diarrhea

frequent passage of loose, watery stools
-abrupt onset of diarrhea immediately after eating suggests acute infection or toxin in the gastrointestinal tract.
-may lead to dehydration
*Treatment: Antidiarrheal drugs

Dysphagia

difficulty in swallowing
-this sensation feels like a "lump in the throat" when a swallowed bolus fails to progress, either because of a physical obstruction or because of a motor disorder in which esophageal peristalsis is not coordinated
Obstructive or

eructation

gas expelled from the stomach through the mouth
also called belching

flatus

gas expelled through the anus
flatulence is presence of excessive gas in the stomach and intestines

Hematochezia

passage of fresh, bright red blood from the rectum
-the cause is usually bleeding due to colitis or from ulcers or polyps in the colon or rectum

Jaundice (icterus)

Yellow-orange coloration of the skin and whites of the eyes caused by high levels of bilirubin in the blood (hyperbilirubinemia)
-Can occur when
1. excessive destruction of erythrocytes, as in hemolysis, causes excess bilirubin in blood
2. malfunction of

melena

Black, tarry stools; feces containing digested blood
-usually reflects a condition in which blood has had time to be digested and results from bleeding in the upper gastrointestinal tracts (duodenal ulcer)
-shows a positive stool guaiac test

nausea

unpleasent sensation in the stomach associated with a tendency to vomit
-sea and motion sickness and early pregnancy
-nausea and vomiting might be symptomatic of a perforation of an abdominal organ; obstruction of a bile duct, stomach, or intestine; toxin

Steatorrhea

fat in the feces; frothy, foul-smelling fecal matter
-improper digestion or absorption of fat can cause fat to remain in the intestine. This may occur with disease of the pancreas (pancreatitis) when enzymes are not excreted.
-It is also a sign of intesti

Aphthous stomatitis

inflammation of the mouth with small, painful ulcers
-commonly called canker sores

dental caries

tooth decay
-dental plaque on the tooth enamel. bacteria frows in the plawue and causes production of acid which dissolves the enamel resulting in a cavity

herpetic stomatitis

Inflammation of the mouth caused by infection with the herpesvirus
-painful fluid-filled blisters on the lips, palate, gums, and tonue, commonly called fever blisters or cold sores

Oral leukoplakia

White plaques or patches on the mucosa of the mouth
- precancerous lesion resulting from tobacco use
-malignant potential is test thru a microscope

Periodontal disease

Inflammation and degeneration of gums, teeth, and bone
- gingivitis occurs from plaque, dental calculus, and tartar
*gingivectomy and antibiotics

Achalasia

Failure of the lower esophagus sphincter (LES) muscle to relax
- results from the loss of peristaltic motion so food cannot pass easily thru the esophagus.
- both the failure of LES and peristalsis leads to the esophagus dilating above constriction
*bland

Esophageal cancer

Malignant tumor of the esophagus
- most common symptom is difficulty swallowing (dysphagia)
- cause: smoking and alcohol, and excessive gastric reflex (Barrett esophagus)
*surgery, radiation, chemotherapy

Esophageal varices

Swollen, varicose veins at the lower end of the esophagus
- liver disease causes increased pressure in veins near and around liver (portal hypertension)
*drug therapy to lower portal hypertension and banding or tying off the swollen esophageal veins

Gastric cancer

Malignant tumor of the stomach
- chronis gastritis associated with bacterial infection is a major risk
-gastric endoscopy and biopsy diagnose
* cure depends on treatment and surgical removal

Gastroesophageal reflux disease (GERD)

Solids and fluids return to the mouth from the stomach
- heartburn is caused from HCl and pepsin regurgitating from stomach into esophagus
- chronic exposure of these acids on the esophageal mucosa leads to reflux esophagitis
* anacids agents and medicati

Hernia

Protrusion of an organ or part thru the muscle normally containing it
-HIATAL HERNIA when upper part of stomach protrudes upward thru the diaphragm. This can lead to GERD
-INGUINAL HERNIA when a small loop of bowel protrudes thru a weak area of lower abdo

Peptic ulcer

Open sore in the lining of the stomach or duodenum
- a bacterium heliobacter pylori, hyperacidity, and gastric juices damage epithelial linings and cause ulcer
* antibiotics, anacids

Anal fistula

Abnormal tube- like passageway near the anus
- results from a break or fissure in the anus or from and absces

Colonic polyps

Polyps (benign growths) protrude from the mucous membrane of the colon
- PEDUNCULATED attached to the membrane by a stalk
SESSILE sitting dire fly on the mucus
*polypectomy and biopsy to prevent malignancy

Colorectal cancer

Adenocarcinoma of the colon or rectum, or both
- can rise from polyps
- diagnosis is determined thru detecting melon (blood in stool) and colonoscopy
- prognosis depends on stage of tumor
* surgical treatment, chemotherapy, and radiotherapy

Crohn disease

Chronic inflammation of the intestinal tract ( terminal ileum and colon)
- symptoms include diarrhea, severe abdominal pain, fever, anorexia, weakness, weightless
- both crohns and ulcerative colitis are forms of IBD
* drugs to control symptoms or surgica

Diverticulitis

Abnormal outpouchings in the intestinal wall
- diverticula ae pouch-like herniations thru the muscular wall of the colon. When fecal matter be ones trapped in -> diverticulitis

Dysentery

Painful, inflamed intestines commonly caused by bacterial infection
- occurring in the colon, occurs from ingestion of food or water containing bacteria
- symptoms bloody stool and abdominal pain

Hemorrhoids

Swollen, twisted, varicose veins in the rectal region
- varicoseveins can be internal or external (outside anal sphincter)

Ileus

Loss Of peristalsis with resulting obstruction of the intestines
- surgery, trauma, or bacterial injury to the peritoneum can lead to paralytic ileus

Intussusception

Telescoping of the intestines
- one segment of bowel collapses into the opening of another segment
- it occurs in children at the oleocecal region
-* surgicAl removal of affected segment with anastamosis

Irritable bowel syndrome (IBS)

Group of gastrointestinal symptoms associated with stress and tension
- diarrhea, constipation, bloating, and/or abdominal pain
- the intestines appear normal but symptoms persist
*symptomatic with a diet high in bran and fiber

Ulcerative colitis

chronic inflammation of the colon with presents of ulcers
- idiopathic, chronic, recurrent diarrheal disease (type of IBS) with rectal bleeding and pain
- beginning in the colon and spreads proximally into the entire colon
* resection of the bowel with il

Volvulus

Twisting of the intestine on itself
- causes intestinal obstruction. Severe pain, nausea, vomiting, and absence of bowel sounds
* surgical correction is necessary to prevent necrosis

Cholelithiasis

Gallstones in the bladder
- calculi (stones) prevent bile from leaving the gallbladder and bile ducts
-many patients are asymptomatic, but if patient has episodes of biliary colic, treatment is required
* laparoscopic cholecystectomy

Cirrhosis

Chronic degenerative disease of the liver
- commonly the result of chronic alcoholism, or viral hepatitis
- lobes of the liver become covered with fibrous tissue, hepatic cells degenerate, and the liver is infiltrated with fat
- cirrh/o means yellow-orang

Pancreatic cancer

Malignant tumor of the pancreas
- occurs more often in men
-cause is unknown
- more common in smokers and obese
- symptoms are abdominal pain, fatigue, jaundice, and anorexia
* pancreatoduodenectomy (whipple procedure)

Pancreatitis

Inflammation of the pancrease
- digestive enzymes attack pancreatic tissue and damage the gland. Others: alcoholism, drugs, gallstones, and viral infections
* meds for epigastric pain, intravenous fluids

Viral hepatitis

Inflammation of the liver caused by A virus
- hep A, B, C
- liver enzyme levels may be elevated, indicating damage to liver cells
-signs and symptoms include malaise, anorexia, hepatomegalgy, jaundice, and abdominal pain

-estasis, -ectasia

stretching, dilation, dilatation, widening
bronchiectasis
lymphangiectasia

-emesis

vomiting
hematemesis

-lysis

destruction, breakdown, separation

-pepsia

digestion
dyspepsia

-phagia

eating, swallowing
polyphagia (excessive appetite)
dysphagia (difficulty swallowing)

-plasty

surgical repair

-ptosis

drooping; sagging; protruding
proptosis (protrusion of the eye)

-ptysis

spitting
hemoptysis (from lungs and respiratory tract)

-rrhage, -rrhagia

bursting forth (of blood)
hemorrhage
menorrhagia

-rrhaphy

suture
herniorrhaphy (stitching up a hernia)

-rrhea

flow, discharge
dysmenorrhea

-spasm

involuntary contraction of mm

-stasis

stopping, controlling
cholestasis (flow of bile from liver is interrupted)

-stenosis

tightening, stricture, narrowing
pyloric stenosis (newborns displaying a blockage in the small intestine)

-tresia

opening
atresia (absense of normal opening)
biliary atresia

Liver function tests (LFTs)

Tests for the presence of enzymes and bilirubin in blood
-ALT: alanine transaminase
-AST: aspartate transaminase
Both AST and ALT are present in many tissue of the body but high levels of both of them indicate damage to liver cells
-Alkaline phosphatase
-

Stool culture

Test for microorganisms present in feces

stool guaiac test or hemoccult test

test to detect occult (hidden) blood in feces
Guaiac is a chemical from the wood of trees and when put in a stool it reacts with any blood present in the feces

Lower gastrointestinal series (barium enema)

x-ray images of the colon and rectum obtained after injection of barium into the rectum

Upper gastrointestinal series

x-ray images of the esophagus, stomach, and small intestine obtained after administering barium by mouth

Cholangiography

x-ray examination of the biliary system performed after injection of contrast into the bile ducts

computed tomography (CT)

a series of x-ray images are taken in multiple views (especially cross section)

Abdominal ultrasonography

sound waves beamed into the abdomen produce an image of abdominal viscera

endoscopic ultrasonography (EUS)

use of an endoscope combined with ultrasound to examine the organs of the gastrointestinal tract

Magnetic resonance imagine (MRI)

Magnetic waves produce images of organs and tissues in all 3 planes of the body

Gastric bypass or bariatric surgery

Reducing the size of the stomach and diverting food to the jejunum (gastrojejunostomy)

Gastrointestinal endoscopy

visual examination of the gastrointestinal tract using an endoscope

Laparoscopy

visual (endoscopic) examination of the abdomen with a laparoscope inserted thru small incisions in the abdomen

Liver biopsy

Removal of liver tissue for microscopic examination

Nasogastic intubation

insertion of a tube through the nose into the stomach

Paracentesis (abdominocentesis)

Surgical puncture to remove fluid from the abdomen

BE

Barium enema

BM

bowel movement

BRBPR

Bright red blood per rectum
Hematochezia

CT

computed tomography

EGD

esophagogastroduodenoscopy

ERCP

endoscopic retrograde cholandiopancreatography

EUS

endoscopic ultrasonography

FOBT

fecal occult blood test

G tube

gastrostomy tube

GB

Gallbladder

GERD

gastroesophageal reflux disease

LAC

laparoscopic-assisted colectomy

LFTs

liver function tests- alk phos, bilirubin, AST, ALT

MRI

magnetic resonance imaging

NG tube

nasograstric tube

NPO

nothing by mouth (nil per os)

PEG tube

percutaneous endoscopic gastrostomy tube (feeding tube)

PEJ tube

percutaneous endoscopic jejunostomy

PTHC

Percutaneous transhepatic cholangiography

PUD

Peptic ulcer disease

TPN

Total parenteral nutrition

T tube

Tube placed in the bile duct for drainage into a small pouch (bile bag) on the outside of the body