IB Biology HL Biochemistry

Define Organic Compound

A compound that contains carbon and is found in living things

components of carbohydrates

C, H, O

components of proteins

C, H, O

components of lipids

C, H, O, N

components of nucleic acids

C, H, O, N, P, S

Monomers of carbohydrates

monosaccharides

Monomers of proteins

amino acids

Monomers of lipids

fatty acids and monoglycerides

Monomers of nucleic acid

nucleotides

Function of carbohydrate

energy

Function of protein

everything

Function of lipid

store energy, structure, insulation

Function of nucleic acid

store genetic information

Example of crabohydrate

Glycogen, cellulose, starch, chitin

Example of protein

enzymes

Example of lipid

wax, oil, fat, steriods

Example of nucleic acid

DNA and RNA

Monomer + Monomer =

Polymer (Condensation Reaction)

Anabolism (Condensation)

Metabolic pathways that construct molecules, requiring energy.

Catabolism (Hydrolysis)

Metabolic pathways that break down molecules, releasing energy.

What type of bonds does Hydrolysis Break

Covalent

Are electrons shared equally in a water molecule

no bitch

Why does Oxygen attract electrons more strongly in a water molecule

because it has a higher electronegativity

why is water described as polar?

because it has a slight difference in charge across its poles

what bonding holds water molecules together

hydrogen bonding

Thermal Properties of water

Water can absorb much heat before changing state (requires breaking of hydrogen bonds)

Cohesive/adhesive properties of water

Water will 'stick' to other water molecules (cohesion) and charged substances (adhesion)

Solvent properties of water

Water dissolves polar and ionic substances

What type of substances is water able to dissolve

Polar and Ionic

Hydrophobic

Water molecules are more strongly attracted to each other than that of the non polar molecule

Hydrophilic

Attracted to water

Function of Monosaccharide

Energy

Function of Disaccharide

Transport

Function of Polysaccharide

Storage

Types of Monosaccharide

glucose
galactose
fructose

Types of Disaccharide

maltose
lactose
sucrose

Types of Polysaccharide

starch
glycogen
cellulose
chitin

Glycerol + 3 Fatty Acids =

Triglyceride + 3H20

How do animals store triglycerides

as fats (solid)

How do plants store triglycerides

as oils (liquid)

what is the largest class of lipids and function primarily as long-term energy storage molecules

Triglycerides

Body Mass Index Formula

Mass (kg)/(Height in m)^2

Saturated Fatty Acids

A fatty acid in which all carbons in the hydrocarbon tail are connected by single bonds and the maximum number of hydrogen atoms are attached to the carbon skeleton.

Unsaturated Fatty Acids

A fatty acid possessing one or more double bonds between the carbons in the hydrocarbon tail. Such bonding reduces the number of hydrogen atoms attached to the carbon skeleton.

cis fatty acids

Hydrogens on the same side of the double bonds

trans fatty acids

Hydrogens on different side of the double bonds

glucose + glucose =

maltose + H20

Glucose + Galactose =

lactose + H20

Glucose + fructose =

sucrose + H20

Amylose Starch

1,4 linkage
unbranched

Amylopectin Starch

1,6 linkage
branched

how many bonds does H have

1

How many bonds does O have

2

How many bonds does N have

3

How many bonds does C have

4

Explain why water is liquid at STP

hydrogen bonds that hold water together are weak, so water has no set structure or shape

Why is sweating a cooling process?

Large amounts of heat are needed to break hydrogen bonds and evaporate water

List the properties of water

cohesive
adhesive
surface tension
high specific heat
high boiling point
high latent heat of vaporization

Solute

A substance that is dissolved in a solution.

Solvent

A liquid substance capable of dissolving other substances

lipoproteins

clusters of lipids associated with proteins that serve as transport vehicles for lipids in blood

How are water molecules dipoles?

They have 2 poles, positive hydrogen and negative oxygen, therefore they show dipolarity

What 3 elements do monosaccharides contain?

carbon, hydrogen, and oxygen
1:2:1 ratio

Monounsaturated Fatty Acid

one double bond

Polyunsaturated Fatty Acid

two or more double covalent bonds

Reasons Trans-fats cause health issues

can cause coronary heart diseas (CHD)

There are how many types of amino acids?

20

All amino acids contain what?

An amine group (NH2)
A carboxylic acid group (COOH)
A hydrogen atom (H)
A variable side chain (R group) (R)

Amino acids are linked together by condensation to form ________________________

polypeptides

what is the covalent bond between amino acids called

a peptide bond

long chains of covalently bonded amino acids are called ____________________

polypeptides

are lipids non polar or polar

non polar

Primary structure of a protein

Simple polypeptide chain

Secondary structure of a protein

Beta structure (fan fold) or alpha structure (double helix)

Tertiary structure of a protein

protein starts to fold itself (no longer linear)

Quaternary structure of a protein

Add to other tertiary structures

Fibrous protein

Long chains of polypeptide, muscle fibers and ligaments

Globular protein

Large, complex, 3D, dissolves in water

Effect of temperature on proteins

High temperature disrupts the hydrogen bonds that hold the protein together

Effect of pH levels on proteins

Changing the pH will alter the charge of the protein, which in turn will alter protein shape and function

one gene will code for one _______________________

polypeptide

proteome

an organism's complete set of proteins

The proteome is always significantly larger than ________________________

the number of genes in an individual

example of protein function

Structure
Hormone
Immunity
Transport
Sensation
Movement
Enzymes

define enzyme

a globular protein which acts as a catalyst by speeding up the rate of a chemical reaction

substrate

the molecule an enzyme reacts with

active site

the region on the surface of the enzyme which binds to the substrate molecule

The active site and the substrate complement each other in both

shape and chemical properties

collision frequency

Increasing the molecular motion of the particles
Increasing the concentration of particles

Catalysis only occurs when? Why?

When substrates are in liquid so their molecules are in continual motion and there is a chance of collision

Immobilized enzymes

Enzymes that are controlled by the attachment of other material to resist movement
Used in industry

Factors affecting enzyme activity

Temperature
pH
Substrate concentration

Effect of temperature on enzymes

Every 10 C increase, enzyme activity doubles because particles are moving faster. Enzymes denature when too hot

Effect of pH on enzymes

Optimum is 7
Below 7 the acidity denatures the enzymes
Above 7 alkalinity denatures the enzymes

Effect of substrate concentration on enzymes

As concentration increases, so does enzyme activity, but after a certain point the active sites are occupied so it is limiting

Allosteric site

Change its shape to either activate or inactivate

Competitive inhibitor

Block substrates by mimicking them

Non competitive inhibitor

Change the shape of an enzyme