Endocrine System

Growth Hormone (GH)

increases growth, body size; many targets

thyroid stimulating hormone (TSH)

stimulates thyroid gland

adrenocorticotropic hormone (ACTH)

stimulates adrenal cortex

follicle-stimulating hormone (FSH)

female-stimulates development of ovarian follicles
male-regulates sperm production and maturation

luteinizing hormone (LH)

female-stimulates ovulation; stimulates production of female sex hormones (estrogen and progesterone)
male-stimulates production of male sex hormones (testosterone)

prolactin

female-production of milk by mammary glands
male-may function to maintain male reproductive tract

pars imtermedia

intermediate lobe

melanocyte stimulating hormone (MSH)

stimulates melanin production

neurohypophysis

posterior lobe

oxytocin

milk ejection and release

vasopressin (antiduretic hormone or ADH)

increases water reabsorption (kidney)

thyroid

inferior to larynx, 2 lobes with connecting isthmus

thyroxin

increases cellular metabolism

calcitonin

decreases blood calcium levels (1. inhibits osteoclasts; 2. stimulates calcium excretion at the kidney)

parathyroids (4)

embedded in posterior surface of thyroid lobes

parathyroid hormone

increases blood calcium levels (1. stimulates osteoclasts; 2. inhibits calcium excretion at kidney; 3. promotes intestinal absorption of calcium)

Pancreas

organ posterior to stomach; near duodenum

insulin

beta cells; decreases blood sugar levels (by increasing glucose uptake)

glucagon

alpha cells; increases blood sugar levels (by breakdown of stored glycogen in liver)

somatostatin

delta cells; inhibits production and secretion of insulin and glucagon

pancreatic polypeptide

F cells; regulates production of pancreatic digestive enzymes

adrenals (2)

superior pole of kidney

mineralcorticoids

zona glomerulosa; aldosterone; regulates salt and water balance at kidneyy

glucocorticoids

zona fasiculata; cortisol; regulates metabolism, immune/inflammatory processes

sex hormones (zona reticularis)

small amounts of testosterone

epinephrine and norepinephrine

affects smooth muscle, glands, mobilizes energy (1. increases heart rate and blood pressure, 2. glycogen breakdown, 3. pupillary dilation, 4. decreases GI motility)

pineal

near posterior midbrain

melatonin

involved in regulation of sleep/wake cycles, circadian rhythms

estrogen

regulates ovarian cycle; promotes secondary sex characteristics and sex drive

progesterone

regulates ovarian cycle; prepares uterus for pregnancy

inhibin

inhibits FSH secretion

Testosterone

stimulates spermatogenesis, growth and development. promotoes and maintains secondary sex characteristics

renin

involved in regulation of blood pressure

erythropoietin

stimulates red blood cell production by bone marrow

calcitriol

increases blood calcium levels (stimulates calcium and phosphorus absorption at GI tract)

atrial natiuretic peptide (ANP)

decreases blood pressure (1. suppresses release of vasopressin and aldosterone, 2. promotes sodium and water loss at kidney)