Motor Unit Dysfunction

Result of polio damage

flaccid paralysis
Sensation intact

Brachial Plexus injury severely affect

upper extremity as contains all nerves that serve the arm leading to paralysis and pain

Motor Unit made up of

Motor neuron
Muscle fibers it innervates

Elementary functional unit in the motor system

Motor unit

Neuromuscular Junction

point at which nerve fiber contacts a muscle cell

Motor Unit Diseases result in

Muscle weakness
Muscle atrophy
Complications associated with loss of muscle function

Two types of Motor unit diseases

Neurogenic
Myopathic

Neurogenic

motor unit disease originating in the nerves, causing the nerve to not work correctly

Myopathic

motor unit disease originating in the muscle, causing neuromuscular junction to malfunction or muscle fibers to malfunction

Type of motor unit disease

Poliomyelitis

Poliomyelitis cause

polio virus

Poliomyelitis damages

anterior horn cells of gray matter in spinal cord

Polio mostly affects

Lower Extremities
Accessory muscles of respiration
Swallowing muscles
Muscle atrophy
Contractures common

Post polio Syndrome

characterized increased weakness of muscles that were previously affected by the polio infection

Causes of neurogenic motor unit diseases

Nerve root compression
Trauma
Toxins
Infection
Neoplasms
Vascular disorders
Degenerative CNS diseases
Congenital malformations

Types of Trauma causing Neurogenic motor unit diseases

bone fractures and dislocations
Lacerations
Traction
Penetrating wounds
Friction

OT interventions generally occur

after acute phase of disease

Positioning intervention for Polio

reduce skin breakdown, pain, and joint deformities and to promote function

Positioning intervention of polio promotes function

Bed positioning
Wheelchair positioning -type and cushion
Splinting

ROM and Strengthening intervention for Polio

Progress from PROM to AAROM to AROM to resistance exercises
No resistance until full ROM against gravity
Focus on correct movement, avoid compensatory movements (use mirror, follow with stretching)

Rationale for ROM and strengthening intervention for Polio

Strengthen unaffected muscles to compensate for deficits
Maximize use of affected muscles

Fatigue management intervention for polio

assistive devices
Task simplification
Environmental modifications
Splints
Mobile arm supports

ADL training intervention for Polio

Teach compensatory strategies
Encourage exploration of leisure interests
Adaptive equipment training
Transfer training

Guillain-Barre Syndrome define

acute inflammatory condition involving the spinal nerve roots, peripheral nerves, and possibly cranial nerves

Guillain-Barre Syndrome follows

viral infection, vaccinations, or post-surgery

Guillain-Barre Syndrome onset

Rapid
Starts with pain and tenderness in muscles
Proceeds to weakness and paralysis
Sensory loss and muscle atrophy
In serious cases, respiratory failure

Recovery for Guillain-Barre Syndrome

within a few weeks to a few months

Guillain-Barre intervention rehab begins

after patient is medically stable
May still be totally paralyzed

Early phase Guillain-Barre interventions

Prevent contractures, deformities and protect weak muscles
Passive activities

Early phase prevention interventions for Guillain-Barre

PROM
Positioning
Splinting

Early phase passive activity interventions for Guillain-Barre

Watch TV
Visit friends
Encourage leisure pursuits to improve outlook and engage in environment

Active movement starts returning interventions Guillain-Barre

Gentle, non-resistive activities
Light ADL's (wipe with washcloth, assist in dress)
Avoid fatigue

Rationale of interventions as active movements begins to return with Guillain-Barre

alleviate stiffness and atrophy
Prevent contractures
Improve strength
Improve psychological outlook

Increase of activity tolerance interventions in Guillain-Barre

AROM and light exercise
Joint protection
Table-top activities/crafts
ADL's (using mobile arm supports and overhead suspension slings)
Guard against fatigue
Upgrade slowly until able to work on full body dressing, bathing, functional mobility

As activity tolerance increases, intervention for Guillain-Barre precaution

Inflamed nerves aggravated by too much work
Joint protection

Peripheral Nerve Injuries

Damage along nerves of the PNS anywhere from spinal nerves to the distal extremities

Area of body nerve goes to in peripheral nerve injuries will have

Weakness or flaccid paralysis
Muscle atrophy
Loss of deep tendon reflexes
Loss of sensation
Paresthesia,
Dry skin, hair loss, brittle nails
Slow healing wounds
Loss of sweating
Contractures, deformities, joint stiffness

Medical management of peripheral nerve injuries

Nerve grafts
Microsurgery
Injections

Peripheral nerve regeneration

begins 1 month after injury

Peripheral nerve regeneration rate

� inch to 1 inch per month

Factors in peripheral nerve regeneration

severity of injury
Surgical intervention
Proximal faster than distal
Age

Signs of Nerve regeneration

skin color and texture improve
Gross recognition of pain, temp, pressure and touch
Paresthesia distal to injury
Scattered points of sweating
Discriminative sensations-localized touch, proprioception, sterognosis
Flaccidity decrease, muscle tone increase
A

Brachial Plexus injury

affects entire upper limb

Long Thoracic Nerve Injury

affects shoulder girdle

Radial Nerve Injury

Affects all extensors of elbow and forearm

Median nerve injury

affects hand and finger flexors

Ulnar Nerve injury

affects hand and finger flexors

Axillary Nerve injury

affects shoulder joint

Tibial Nerve injury

affects plantar flexion of ankle

Sciatic Nerve injury

affects muscles of leg and foot

Peroneal Nerve injury

affects dorsiflexors

Femoral Nerve injury

affects hip flexion and knee ext.

Brachial Plexus injury often caused in children

birth trauma

Brachial Plexus injury in football

Stinger

Klumpke's paralysis

Brachial Plexus injury (c8-T1) characterized by paralysis to distal musculature of the wrist flexors and intrinsic muscles of hand

Erb's Palsy

Brachial plexus (C5 &C6 roots)
Characterized by a limp arm with hand rotating medially

Long Thoracic Nerve Injury define

Long Thoracic Nerve innervates in Serratus Anterior Muscle of shoulder girdle resulting in weakness or paralysis and "winging" of scapula.

Interventions for Long Thoracic Nerve injury

Surgery
OT focus on maximize functional independence with long handled devices.
OT also help with progressive strengthening.

Axillary Nerve Injury Definition

Innervates deltoid and teres minor
Weak abduction, external rotation and horizontal abduction
Atrophy of deltoid
Hyperesthesia of area

OT intervention of Axillary Nerve injury

Maintain ROM to prevent deformity and improve circulation
Dressing training

How to prevent deformity and improve circulation for Axillary Nerve Injury

Protect Deltoid and Teres minor from over stretch
Start with AROM, progress to AROM and eventually strengthening exercises
With surgical transplant of tissue, helpful for EMG feedback

Sciatica

condition characterized by pain and electricity traveling down the leg along the course of the sciatic nerve.

Foot Drop

inability to dorsiflex the ankle
Caused by peripheral nerve injuries or by central nervous system condition.
Use AFO splint to keep ankle in neutral position

Pain in Peripheral Nerve pain Syndromes

common complication of PN injuries

Two types of pain syndromes

Complex Regional Pain syndrome
Neuroma Pain

Complex Regional Pain syndrome

also known as Causalgia or Reflex Sympathetic Dystrophy
After injury, intense pain and sensitivity develops far greater than expected for the injury
Is cyclical

Symptoms of Complex Regional Pain Syndrome

Pain, burning, extreme sensitivity to temperature, wind and even noise
Often holds limb to guard it against any trigger of pain.
Area often shiny and puffy

Neuroma pain

nerve tissue tumor or growth
Often occurs with incompletely healed nerve endings after injury
Common in fingers and amputated limbs
Phantom limb pain often result of neuroma formation

Interventions for Peripheral Nerve pain

Graded sensory input
Purposeful activities to provide cognitive diversion from experience
Background music or headphones during activities affect pain intensity

Types of Graded sensory input

Tapping/vibration
TENS
Instruction on protecting tender areas during ADL's

CRP associated with

tension and stress

Intervention in CRPS

Relaxation techniques

Types of useful relaxation techniques for CRPS

Deep breathing
Progressive relaxation
Guided imagery

Reason Relaxation works for CRPS

muscles relax, heart rate and respiration rate slow, general sense of well being
Give patient control over emotional tension and depression

Intervention for CRPS

Scrubbing exercises
Carrying exercises

Myasthenia Gravis

autoimmune disease that affects receptors at neuromuscular junction so muscles can't receive signals from motor nerves

Myasthenia Gravis symptoms

Fatigue of voluntary muscles
Targets muscles of eyelids, eyes, oropharyngeal muscles, tongue, jaw and throat
Affects more proximal muscles
Respiratory paralysis in severe cases

Main OT goal for MG

regain muscle power and build endurance

Avoid in Myasthenia Gravis

fatigue and respiratory exertion

Interventions for Myasthenia Gravis

Gentle, non-resistive activities that are intellectually and psychologically stimulating
Energy conservation, work simplification
Adaptive devices to reduce effort during ADLs
Home modifications
Mobile arm supports and splints to assist weakened muscles a

Muscular Dystrophies

degeneration of muscle fibers. Nerves for motor actions and sensation remains

Types of Muscular Dystrophies

Duchenne's
Becker's
Facioscapulohumeral
Myotonic
Limb-Girdle

OT interventions for Muscular Dystrophy

Decline of muscle function unable to be stopped
Delay deformity and achieve maximum function within disease limits
Focus on maintain maximum function
Patient/Family Training

Patient and Family Training for Muscular Dystrophy

Gentle passive stretch
Body alignment and joint integrity
Bed and wheelchair positioning to prevent contractures (hip, trunk, extremities)

ADL intervention for Muscular Dystrophy

Practice dressing, toileting, bathing to maintain skills and independence
Feeding and leisure
Compensate for weakness

Ways to compensate for weakness in Muscular Dystrophy

Built-up utensils for weak grip
Suspension sling and mobile arm support
Wheelchair lap-board to support reading, writing, games, crafts