Chapter 21: Lymphatic System

3 functions of lymphatic system

immunity, fluid recovery, liquid absorption

clear, colorless fluid, similar to plasma but much less protein

lymph

2 types of collecting ducts

right lymphatic duct and thoracic duct

lymphatic cell responsible for immune surveillance

NK cell

cell that matures in thymus

T cell

cell that matures in bone marrow and produces antibodies

B cell

primary lymphatic organs

red bone marrow and thymus

secondary lymphatic organs

lymph nodes, tonsils and spleen

3 types of tonsils

palatine, lingual, pharyngeal (adenoid)

the type of immune response that is broadly effect and has no prior exposure- no memory

nonspecific

the type of immune response that results from prior exposure and protects against only a particular pathogen

specific

what are the orders of defense?

external barriers, phagocytic cells/antimicrobial proteins/inflammation/fever, immune system

leukocyte which phagocytizes bacteria- nonspecific- and creates a killing zone with degranulation and respiratory burst

neutrophil

leukocyte which phagocytizes antigen-antibody complexes and has antiparasitic effects; blocks excess inflammation

eosinophil

leukocyte which aid mobility and action of WBCs by release of histamine and heparin which increase blood flow to tissue and prevents immobilization of phagocytes. helps in inflammation

basophil

leukocyte which is the circulating precursor to macrophages

monocyte

leukocyte which include b and t cells

lymphocytes

complement system is _________

nonspecific

chemicals released thru inflammation

cytokines

4 cardinal signs of inflammation

redness, swelling, heat, pain

inflammations 3 major processes

mobilization of body defenses, destruction, tissue repair

stages of fever

onset, stadium, defervescence

cell-mediated immunity

cellular

antibody mediated immunity

humoral

production of one's own antibodies or T cells as result of infection

natural active immunity

production of one's own antibodies or T cells as result of vaccination

artificial active immunity

temporary, fetus acquires antibodies from mother

natural passive immunity

temporary, injection of immune serum (antibodies)

artificial passive immunity

chemicals which are foreign to the body and trigger an immune response

antigens

______ and ______ display antigens to T cells

b cells and macrophages

chemical messengers that communicate between leukocytes

interleukins

which type of cell have memory have past infections?

t cells

3 classes of t cells

cytotoxic, helper, memory

the t cells which carry out the attack

cytotoxic

the t cells which promote tc cell and b cell action and nonspecific defense

helper

the t cells which provide immunity from future exposure to antigen

memory

3 components of immunity

recognition, attack, memory

antibody in mucus, saliva, tears, milk

IgA

antibody in antigen receptor

IgD

antibody which stimulates release of histamines

IgE

antibody which crosses placenta to fetus

IgG

antibody which is responsible for immune response, agglutination (transfusion reactions) complement fixation

IgM

4 methods of attack in humoral immunity

neutralization, complement fixation, agglutination, precipitation

humoral attack where antibodies mask the active pathogenic region of antigen

neutralization

humoral attack where the antigen binds to IgM or IgG and changes shape

complement fixation

humoral attack where antibody binds to multiple enemy cells to immobilize them

agglutination

humoral attack where antibody binds to antigen molecules and creates antigen-antibody complex which is phagocytized by eosinophil

precipitation