Chapter 6 - Introduction to the Skeletal System

Skeletal System

system comprised of all the bones, their cartilage, ligaments, and tendons.

Red bone marrow

one marrow located that produces red and white blood cells and platelets.

Yellow bone marrow

bone marrow that stores triglycerides.

Hemopoiesis

the process in which red bone marrow produces red blood cells, white blood cells, and platelets.

Diaphysis

the shaft or body section of the bone.

Epiphyses

the proximal and distal ends of the bone.

Metaphyses

the section of bone between the diaphysis and epiphyses.

Epiphyseal plate

Growth plate, made of cartilage, gradually ossifies into the epiphyseal line.

Epiphyseal line

a line of cartilage present at the junction of the diaphysis and epiphyses; a remnant of the epiphyseal plate.

Articular cartilage

Hyaline cartilage attached to bones at articulating joints.

Periosteum

a tough connective tissue surrounding the bone surface where it is not covered by articular cartilage

Medullary cavity

this cavity is the hollow, cylindrical space within the diaphysis that contains yellow bone marrow in adults.

Endosteum

membranous lining of the hollow cavity of the bone; contains bone-forming cells.

Osseus Tissue

also called bone tissue.

Hydroxyapatite

Hardy crystals consisting of calcium and phosphate that form the bone matrix.

Calcification

process that hardens bones by adding calcium phosphate and collagen.

Osteogenic cells

are the unspecialized stem cells that develop into osteoblasts.

Osteoblasts

bone building cells

Osteocytes

mature bone cells

Osteoclasts

bone-destroying cells

Compact bone tissue

type of bone tissue with few spaces and is the strongest form of osseous tissue.

Osteons

structural units of mature compact bone

Central canal

longitudinal channel in the center of each osteon; contains blood vessels, nerves, and lymphatic vessels; also known as the Haversian canal

Concentric lamellae

Calcified extracellular matrix arranged in multiple layers or rings; makes up the osteons

Lacune

spaces in bone matrix that house mature osteocytes

Canaliculi

extensions of the lacunae and are filled with extracellular fluid.

Spongy bone tissue

type of bone tissue that does not contain osteons; always located in the interior of bones; consists of trabeculae.

Trabeculae

lamellae arranged in irregular lattice in thin columns in spongy bone tissue.

Periosteal arteries

These arteries enter at numerous points to supply the compact bone.

Perforating canals

structures through which blood vessels enter and exit the bone shaft.

Interstitial lamellae

remains of old osteons that have been partially destroyed.

Circumferential lamellae

outer surface of compact bone; thin plates that extend around the bone.

Nutrient artery

large artery that enters compact bone near the middle of the diaphysis to deliver blood.

Nutrient foramen

a hole near the center of the diaphysis in which the nutrient artery and vein passes through.

Metaphyseal arteries

enter the metaphyses of a long bone and, together with the nutrient artery, supply the red bone marrow and bone tissue of the metaphyses.

Epiphyseal arteries

enters the epiphyses of a long bone and supplies red marrow and bone tissue of the epiphysis.

Nutrient veins

vein that enters the compact bone near the middele of the diaphysis to carry away blood.

Epiphyseal veins

veins that carry blood away from long bones

Metaphyseal veins

veins that exit through the metaphysis.

Periosteal veins

small veins that exit through the periosteum.

Ossification

the process of bone formation.

Mesenchyme

embryonic connective tissue from which all other connective tissues arise.

Intramembranous ossification

the process of bone formation directly within mesenchyme.

Endochondral ossification

the process of bone formation within hyaline cartilage that develops from mesenchyme.

Ossification centre

area in the cartilage model of a future bone where the cartilage cells hypertrophy, secrete enzymes that calcify their extracellular matrix, and die, and the area they occupied is invaded by osteoblasts that then lay down bone.

Chondroblast

immature cells that secrete the extracellular matrix of cartilage.

Hyaline cartilage model

a model produced by chondroblasts secreting cartilage extracellular matrix.

Perichondrium

a covering that develops around the hyaline cartilage model.

Primary ossification centre

the region that develops in the mid-region of the cartilage model where osseous tissue will replace cartilage.

Secondary ossification centre

the region that develops in the epiphyses, where bone replaces cartilage.

Bone remodelling

the ongoing replacement of old osseous tissue by new osseous tissue

Sex hormones

progestrone, estrogen, and testosterone

Parathyroid hormone

a hormone of the parathyroid gland that regulates the metabolism of calcium and phosphorus in the body.

Calcitonin

hormone from the thyroid gland that has the potential to decrease blood calcium level.

Long bone

bone of greater length than width and consists of a shaft and two extremities.

Short bone

cube shaped bone.

Flat bone

thin bone that can afford considerable protection.

Irregular bone

bone of complex shape and cannot be grouped into other categories.

Sesamoid bone

bone shaped like a sesame seed.