Which of the following would most accurately describe the state of a sarcomere if myosin were mutated such that it had a much higher affinity for ADP but a normal affinity for Pi?
The myosin head will be engaged in a cross-bridge to the thin filament but prior to the power stroke.
Microfilaments
are composed of two helical strands of actin monomers oriented in the same direction
Rho Family GTPases (Rho, Rac, Cdc42) stimulate cytoskeletal microfilament assembly for all of the following except
nuclear envelope breakdown for mitosis
Tubulin may assemble onto one end while disassembling from the other end of the same microtubule simultaneously in a process known as
treadmilling
The ________ is the organelle that fuses with endosomes and supplies hydrolytic enzymes necessary for the digestion of the materials
lysosome
The two main types of eukaryotic microtubules are the ________ and ________ microtubules.
cytoplasmic and axonemal microtubules
Which of the following is the correct order of events in a crawling cell?
protrusion at the cell's leading edge, attachment of protrusion, pulling the cell forward, release and retraction of trailing edge
What are the 3 types of secretion discussed in class. Give a sentence or 2 describing each type.
Constitutive - Some vesicles move directing to the cell surface and immediately fuse with the plasma membrane after budding from TGN. Regulated - Secretory vesicles first accumulate in the cell and fuse with the plasma membrane only in response to specifi
During the sliding process in microtubules in cilia and flagella, the stalks of an axonemal dynein attach to, produce force on, and detach from a(n) ________ in a cyclic manner.
B Tubule
________ is a drug that blocks cell division by stabilizing microtubules; as a result, it is used in the treatment of ________
Taxol; breast cancer
What is a SNARE protein? How is it important for cells?
SNARE protein are a large protein complex consisting of at least 24 members in yeasts and more than 60 members in mammalian cells.SNARE Proteins Mediate Fusion Between Vesicles and Target Membranes. These proteins are essential for vesicle fusion at the p
Which of the following statements is false regarding phagocytosis?
It is mediated by clathrin at the plasma membrane
Which of the following is not a function of the cytoskeleton?
passive transport
How do cells maintain a low pH inside lysosomes? (Give me the name of this protein)
ATPases pumps H+ into the lysosome so that pH decreases, and maintains an acidic environment.
Motility may involve
shortening of a cell
movement of components within a cell
movement of the environment past a cell
movement of a cell/organism through its environment
All of the above are correct
Which of the following microtubule-interacting proteins would you target to disrupt cell division in actively replicating tumor cells
MCAK (a catastrophin)
Which of the following is false about dynamic instability of a microtubule end?
During a catastrophe phase, hydrolysis of incorporated GTP is faster than GTP-tubulin addition, forming a GDP-cap
During a growth phase, assembly of GTP-tubulin is faster than
All of the above are true