Quiz gen

In genetics, all of the genes on a single chromosome. They are inherited as a group; that is, during cell division they act and move as a unit rather than independently.
The existence of linkage groups is the reason some traits do not comply with Mendel's

Linkage group

The law of "Independent Assortment".
It is also possible for some of your children to inherit new combinations called "re-combinants" from you.
the principle applies only if genes are located on different chromosomes.

The second Mendelian law

cross

N2 males X dpy-13 hermaphrodites
-->
dpy-13/+ males X RW7000 hermaphrodites
-->
two classes of sperms and one class of oocytes
dpy-13 and WT WT 1
-->
two classes of hermaphrodite progeny
dpy-13 sperm. WT sperm
WT 1 oocytes. WT 1 oocytes

PCR

If you pick up Dpy worms to do PCR, 75% of them will amplify marker 2, but none of them will show the presence of marker 1.

crossing over

Process in which homologous chromosomes exchange portions of their chromatids during meiosis.

When does crossing over occur?

prophase I of meiosis

Probability

P(A ? B): Probability that event A and/or event B occurs.This is also known as the probability of the union of A and B.P
(A ? B): Probability that event A and event B both occur.This is also known as the probability of the intersection of A and B.

conclusion

If dpy-13 mutation is on the chromosome where marker 1 localizes, the chance to detect thepresence of marker 1 in Dpy worms is around 0.75 X recombination frequencybetween dpy-13 and marker 1 .The chance to detect the presence of marker 2 in Dpy worms is

what causes dip-13 mutant?

a deletion aprox 30 bp