Chap 1 Patho

Primary prevention:

Actions aimed at prevention of disease.
Seat belt, chlorination and fluoridation of water, sunscreen, helmet, nutritious diet, taking vitamins, washing of hands.

Secondary prevention:

Actions (mainly, screening) aimed at early detection and prompt treatment of disease.
Pap smear, mammogram, physical

Tertiary prevention:

Treatment and rehabilitation measures aimed at preventing further progress of the existing disease.
Chemotherapy, surgery, radiation, blood transfusion

Etiology

the cause; one half of pathogenesis

Risk Factors

are multiple factors that predispose to a particular disease.

Diagnosis vs. Nursing Diagnosis

Is the designation or LABEL as to the nature or cause or a health problem.
vs.
A designation/label that focuses on the HUMAN RESPONSE to the condition.

Clinical manifestations

Signs and Symptoms

Sign

an observable/measurable expression of the altered health condition; a manifestation that is noted by an observer.
An elevated temperature, a swollen extremity, and changes in pupil size
OBJECTIVE

Symptoms

is a complaint/indicator that is reported by the ill person
Pain, difficulty breathing, and dizziness
SUBJECTIVE

Syndrome

a cluster of clinical manifestations, labs, diagnostic tests that fit a recognizeable & predictable pattern; is a compilation of signs and symptoms that are characteristic of a specific disease state
TYPE OF MEDICAL DIAGNOSIS

Complications

are possible adverse extensions of a disease or outcomes from treatment

Sequelae

are lesions or impairments that follow or are caused by a disease.

Clinical Course

Discribes the evolution of a disease (acute, sub acute, and chronic)

Acute

abrupt in onset, lasting a few days to a few months

Subacute

intermediate or between acute and chronic

Chronic course

gradual in onset, occurring over a long period (6 months or more)

Pathophysiology

physiology of altered health states; the functional changes that accompany an injury, syndrome or disease

Pathology

deals with the study of the structural and functional changes in cells, tissues, and organs of the body that cause or are caused by disease/injury
Patho is different from pathophysiology because it looks at how these changes impact the entire body.

Physiology

deals with the functions of the human body

What is the order of the disease process?

Etiology, pathogenesis, morphology, clinical manifestations, and prognosis.

Pathogenesis

origination/development of a disease/illness. HOW THE DISEASE PROCESS EVOLVES (and RESOLVES)

Morphology

refers to the fundamental structure or form of cells or tissue

Morphological changes

refers to the gross anatomic and microscopic changes that are characteristic of a disease.

Clinical manifestation

the way a disease manifest itself.

epidemiology, and the reasons it's important

the study of disease occurrence in human populations
allows us to identify a disease's patterns/causes, & understand how to control it & apply the three levels of prevention.
1. where probs are most prevalent
2. who is most affected
3. WHY said population

Incidence

chance of occurrence; reflects the number or new cases arising in a population at risk during a specified time

Prevalence

what has already occurred; is a measure of existing disease (%) in a population at a given point in time

Morbidity

diseased state; functional effects of a disease on the body; poor quality of life

Mortality

death rate; death producing effect of disease

State the World Health Organization definition of health

state of complete physical, mental, and social well-being and not merely the absence of disease and infirmity.

structure vs. function

Parts & their placement; Actions/workings
Anatomy vs. physiology

8 related sciences (to pathophys)

ABCHMMPP ("ab chimp")
Anatomy
Biology
Chemistry
Histology
Microbiology
Morphology
Pathology
Physiology

histology

study of minute structures of cells/tissues, via microscope; a branch of anatomy.

morphology

study of form/structure of animals & plants; looks at how cells/tissues change in form after encountering disease; a branch of biology

microbiology

study of microscopic forms of life

4 dimensions of human "health

emotional
physical
psychosocial
spiritual

health

being sound in mind, body & spirit

homeostasis

dynamic steady state marked by appropriate regulatory responses in the body

illness

a state resulting from suffering or distress

disease

impairment of cell, tissue, organ or system functioning; disturbance of body structure/function; poses a challenge to homeostasis; presence or absence marked by specific signs/symptoms

risk factors vs. precipitating factors

vulnerabilities vs. triggers; relevant to pathogenesis

idiopathic

lacking a clear cause

nosocomial

illness caused by exposure to a health care environment
(considered a medical error; health insurance won't reimburse for costs related to nosocomial complications.)

iatrogenic

illness that result (inadvertently) from medical treatment
(considered a medical error; health insurance won't reimburse for costs related to nosocomial complications.)

prognosis

forecast/prediction of how the person will proceed through the health condition.

endemic

a condition with stable/predictable incidence/prevalence

epidemic

above the endemic rate; dramatic increase in incidence of a condition.

pandemic

an epidemic spread across continents; ex - H1N1

biomedicine

systematic scientific study of biological processes & western medicine; assumes disease has an identifiable cause & curing the cause will resolve the symptoms.

16 functional concepts of altered health

1. basic alterations in cells/tissues
2. inflammation
3. immunity
4. infection
5. genetic/developmental disorders
6. altered cell proliferation/differentiation
7. altered fluid/electrolyte balance & acid/base balance
8. altered neuronal transmission
9. al

pathologist

physician who specializes in diagnosing/classifying diseases by studying the morphology of cells/tissues.

6 factors impacting variations in health (related to diversity)

age
ethnicity
gender
locale
race
socioeconomic factors

prevention vs. intervention

prevention = stopped the onset/progression of disease
intervention = specific action in relation to treatment of the disease

lesion

well-defined, characteristic structural change in tissue/organs as a result of disease

organic disease vs. functional disease

aka, STRUCTURAL disease; verify via gross/histologic examination
no morphological abnormalities, but body functions are disturbed (ie, indigestion)

5 classes of disease

1. metabolic - hyperthyroidism
2. neoplastic - benign lipoma; malignant lung cancer
3. congenital/hereditary - hemophilia
4. inflammatory - type 1 diabetes
5. degenerative - arthritis