Patho Exam 4

What causes polycythemia in a patient with lung disease?

Chromic hypoxia, causes increase in hematocrit

What conditions are seen most in patients with lung disease?

Hypoxia and hypoxemia

Tension pneumothorax clinical manifestations:

Mediastinal shift / compression
Decreased cardiac output

To get someone ready for hemodialysis what do we do in their arm?

AV fistula

BUN labs

8-20 mg/dL

Creatinine labs

0.6-1.2 mg/dL

GFR labs

90-120 ml/min/1.73m2

Which lab value would we expect to be decreased with chronic renal disease?

GFR

Who would be most at risk for adelectasis?

Surgery, pain meds, anesthetics, infection

What is atelectasis?

Incomplete expansion of lung

hemoptysis

bloody sputum

hypercapnia

excessive carbon dioxide in the blood
WILL BE ACIDOTIC

What is the mechanical effect of pleural effusion?

Compression

What pathological process could cause Kussmaul's breathing?

Metabolic acidosis

Kussmaul breathing

rapid deep breathing

What causes clubbing of the fingers?

chronic hypoxemia, lack of oxygen

Why is tension pneumothorax life-threatening?

Air enters the pleural space during inhalation and does not exit with exhalation. Air accumulates increasing pressure and can collapse lung

What is central cyanosis?

Lips, tongue, tip of nose

SA: clinical manifestations of pleural effusion

Atelectasis
SOA
Pleuritic pain from inflammation
Absent breath sounds at site of effusion
Non-productive cough
Pleural friction rub over areas of effusion
Impaired ventilation
Mediastinal shift
Fluid in pleural space

How do we treat a pneumothorax? How do we get the air out?

Large bore needle or chest tube on the affected side along with one way valve drainage or suction to aid in re-expansion

Who is most at risk for spontaneous pneumothorax?

Men ages 10-30 that are tall and thin

What is the adaptive mechanism of hypoxemia?

Increased heart rate and respiratory rate in order to circulate blood

Hypoxia

Decreased oxygen of cells of tissues

Emphysema

Loss of lung elasticity and hyperinflation of lungs resulting in air trapping, flat diaphragm, Bullae formation, increased work of breathing, and air hunger

hypoxemia

Below normal level of oxygen in your blood, specifically in the arteries

What do you see in a patient with subcutaneous emphysema?

Gas or air travels and is trapped under the skin

What causes respiratory alkalosis?

hyperventilation

What is the major cause of acute respiratory acidosis?

Hypoventilation

In hypoxia, what might the body do to get more oxygen circulating

Increase in RBC count

You are auscultating a patient that had surgery and they are SOA, respirations are high and labored, listening to lung there is an absence of breath sounds. The patient has

Pneumothorax

Best way to get a definitive diagnosis for TB

Obtaining a culture (sputum, GI secretions, bronchial washings)

How does TB transfer?

Airborne, droplet with cough and sneeze

Pathophysiology of bronchiectasis

Permanent dilation of bronchi and bronchioles from muscle and elastic support caused by frequent infection and inflammation

How to test and treat TB?

Treatment: INH most frequently used

What is the best way to manage the spread of TB?

Testing and vaccines

Major risk factor for lung cancer

Smoking, age

Clinical manifestations of renal cell carcinoma

Hematuria, flank pain, flank mass, edema, urine output
Tumor often large when detected
May involve inferior vena cava

Assessment data that would suggest nephrotic syndrome

Massive proteinuria and lipiduria, hypoalbuminemia, edema, hyperlipidemia, generalized edema from decreased colloid osmotic pressure from hypoalbuminemia
Also sodium and water retention resulting systemic and pulmonary edema
Glomerular filtration rate is

Beta Strep infection causes what renal pathology

Renal postinfectious glomerulonephritis

What is the prerenal cause of renal failure

Decreased blood flow to kidneys

What is the post renal cause of renal failure

Obstruction to urine flow from the kidneys- resulting in hydronephrosis (prostate obstruction)

Why does anemia occur with chronic renal failure

Erythropoietin deficiency

What is the bacteria that causes acute cystitis

E. Coli

What is azotemia?

Increase in serum urea, Uric acid, and creatinine

What causes azotemia?

Acute renal injury indicator

Pathophysiology of hydronephrosis

Urine dilates pelvis and calyces of kidney resulting in renal atrophy

GFR

The flow rate of filtered fluid through the kidney each minute

community acquired pneumonia

Onset outside of hospital or within 48 hours of hospital admission

Pathophysiology of asthma

Bronchoconstriction with inflammation

Pathophysiology of pneumothorax

Air in pleural space- from rupture of visceral pleura or parietal pleura and chest wall