Chapter 16 Kidneys

Bilateral retroperitoneal organs that receive blood from renal arteries and drained by renal veins

Kidneys

Micturation

Urination

Drains urine from bladder

Urethra

Produces sperm

Testes

Encircles each teste

Epididymis

Major functional units of kidney contained here

Cortex

Containes specialized distal parts of tububles and collecting tubules

Medulla

Transports urine to the pelvis

Collecting tubules

Upper Urinary Tract refers to

Kidneys

Kidneys are essential for control of

Blood pressure
Excretion of waste products
Mainetence of acid-base balance
Filter blood
Regulate blood composition
Maintain red blood cell levels

How do kidneys perform all their functions

Regulating concentration of salt, water, and hydrogen ions and filtering blood

Basic functional unit of the kidney

Nephron

The three components of a nephron

Glomerulus
Tubules
Associated vessels

Layer of epithelial cells that cover capillaries

Podocytes

All supporting tissue between tubules and glomeruli

Interstitium

Passage of substances from capillaries to tubules

Secretion

Passage of substances from tubules to capillaries

Resorption

Hormone that reduces plasma volume or increases plasma oncotic pressure

Antidiuretic hormone

Collection of cells that secrete renin

Juxtaglomerular apparatus

Result in an increase in blood pressure or blood volume

Renin

Stimulates vasoconstriction and increases blood pressure

Angiotensin

Increases resorption of sodium and water, expands blood volume

Aldosterone

The 2nd most common infection in the human body

UTI

UTI's are caused by bacteria entering through the

Urethra

Pyelonephritis

Infection of the kidneys

Dysuria

Painful

Nocturia

Nightime urination

Oligouria

Decreased urine output

Anuria

Absence of urine production

Urinalysis

Inspection of urine

6 characteristics of normal urine

Bile pigments
Protein absent
Glucose absent
Ketones absent
Odorless
ph 6.0

Prostate enlargment that causes obstruction of the outflow of urine from bladder

Benign prostatic hypertrophy

Stone lodged in renal pelvis, ureters, bladder or urethra that obstruct flow of urine

Kidney stones

Another term for kidney stones is

Calculi

What are kidney stones composed of

Calcium and uric acid

Method of destroying stones by high external shock waves

Lithiotripsy

Irreversible loss of function in the kidneys

End stage renal disease

What causes end stage renal disease

Hypertension and diabetes mellitus

Treatment options for end stage renal disease

Kidney transplant or hemodialysis

What is the 2nd most common death in men

Prostate cancer

Insertion of tubes fitted with lenses and lights through urethra

Cytoscopy

Urinary casts are composed of

RBC
WBC
Tubular cells
Protein or fat

Risk factors of kidney stones

Dehydration
Gout

The part of the kidney in which blood is filtered

Nephron

A 6 year old girl is seen by her pediatrician because her parents notice edema of her ankles. Laboratory testing reveals proteinuria, hypoproteinemia, and hyperlipidemia. She most likely has

Nephrotic syndrome

Most diseases of the glomeruli are caused by

Immune mediated injury

Gleason score is an important prognostic factor in prostate adenocarcinoma. Gleason score

characterizes how aggressive the tumor looks under the microscope

Cryptorchidism should be surgically treated because undescended testicles

have a high risk for developing testicular cancer

Small kidneys with receded size but normal architecture

Renal Hypolasia

When kidneys become fused at their lower poles

Horseshoe kidney

Malformed renal tissue results in

Renal Dysplasia

Less waste is removed when kidneys fail. True or false.

TRUE

Where does waste remain when kidneys fail?

Blood

BUN stands for

Blood urea nitrogen

Renal failure that is sudden and rapidly progressive within hours.

Acute renal failure

Renal failure that is slowly progressing to end stage renal failure over months to years

Chronic renal failure

Retention of nitrogenous waste in the blood is called

Azotemia

Uremia means

Urine in the blood

Decreased blood supply from shock dehydration or vasoconstriction

Prerenal failure

Urine flow is blocked by stones tumors or enlarged prostate

Postrenal failure

Kidney tubule function is decreased by toxins

Intrinsic renal failure

The irreversible loss of renal function that affects nearly all organ systems

Chronic renal disease

Causes of chronic renal disease

Hypertension and diabetes

Treatment for CRF

Dialysis or kidney transplant

Urothelial carcinoma is

Bladder cancer

The most common risk factor for bladder cancer

Smoking

Renal Cell Carcinoma is

Cancer of the kidney in adults

Nephroblastoma is

Cancer of the kidney in children