Headache pharmacology

What is the first line therapy for aborting a migraine attack?

triptans (serotonin 1B/1D receptor agonist)

What do the triptans do

abort a headache attack

What is the second line therapy for aborting a migraine attack?

Ergotamine (ergot alkaloid)

What medication is like a ergot alkaloid but has to be provided by IV, SQ, or intranasally?


What medication is first line for migrane prevention?

B Blockers (propanolol and metoprolol)

What beta blocker is not effective in preventing migranes?

acebutalol and pindolol

What antiepileptic drugs are approved for prevention of migranes?

Divalproex (Depkote ER), toprimate (Topamax)

What type of antidepressants are used for migrane prevention?

Tricyclic antidepressants

What human immunoglobulin G2 monoclonal antibody medication is approved for headache prevention?

Erenumab (Aimovig)

What is the treatment of choice to abort a cluster headache attack?

Sumitriptan SQ injection

What medications are used for cluster headache prevention?

Glucocorticoids (prednisone, dexamethasone), veramil (CCB), and lithium