What is the main prerequisite for clearance at the G2 checkpoint?
An accurate and complete DNA replication has occurred.
In a study on cell division, researchers culture synchronously dividing human cells with thymidine, which causes the cells to arrest at the G1 boundary. The cells are then placed in medium lacking thymidine, which releases the block, and the cells begin t
Sample B
Why might a cell that has just completed cytokinesis enter the G0 phase instead of the G1 phase?
Some cells reproduce only under certain conditions and, until then, they remain in the G0 phase.
The fusing of Golgi vesicles at the metaphase plate of dividing plant cells forms what structure?
Cell plate
Human papillomavirus can cause cervical cancer. The virus encodes E6, a protein that binds p53. Based on this fact and what you know about p53, what effect do you think E6 binding has on p53 activity?
E6 binding marks p53 for degradation.
What is the sequence of mitotic cell cycle for one pair of chromosomes that is undergoing normal mitotic division?
Prophase - metaphase - anaphase - cytokinesis
Which eukaryotic cell cycle events are missing in binary fission?
Karyokinesis
Li-Fraumeni syndrome (LFS1) is a rare hereditary disorder that leads to a predisposition to cancer. This hereditary disorder is linked to mutations in the tumor-suppressor gene encoding the transcription factor p53. p53 acts at the G1 checkpoint. If damag
1. Cell cycle progression
2. p53
3. p21
4. CHK2
Which regulatory mechanisms might be lost in a cell producing faulty p53?
Quality of DNA, triggering apoptosis, and recruiting repair enzymes
What are identical copies of chromatin held together by cohesin at the centromere called?
Sister chromatids