med term ch 12 nervous system pathology

amnesia

loss of memory caused by brain damage or severe emotional trauma

aphasia

lack or impairment of the ability to form or understand speech

athetosis

continuous, involuntary,slow, writhing movement of the extremities

aura

premonition
sensation of light or warmth that may precede an epileptic seizure or the onset of some types of headache

dysphagia

condition of difficulty with swallowing

dyssomnia

disorders of the sleep-wake cycles
insomnia, hypersomnia = excessive depth or length of sleep

fasciculation

involuntary contraction of small, local muscles

abnormal gait

disorder in the manner of walking
e.g. ataxia = lack of muscular coordination, as in cerebral palsy

hypokinesia

decrease in normal movement; may be due to paralysis

neuralgia

nerve pain
causalgia = burning pain

paresthesia

feeling of prickling, burning, or numbness

seizure

neuromuscular reaction to abnormal electrical activity within the brain
causes: fever or epilepsy
also convulsions

spasm

involuntary muscle contraction of sudden onset
e.g. hiccoughs, tics, and stuttering

syncope

fainting
vasovagal attack = results from abrupt emotional stress involving the vagus nerve's effect on blood vessels

tremors

rhythmic, quivering, purposeless skeletal muscle movements seen in some elderly individuals and in patients with various neurodegenerative disorders

vertigo

dizziness
abnormal sensation of movement when there is none, either of oneself moving, or of objects moving around oneself

acalculia

inability to perform mathematical calculations

ageusia

absence of the ability to taste
parageusia = abnormal sense of taste or a bad taste in the mouth

agnosia

inability to recognize objects visually, auditorily, or with other senses

agraphia

inability to write

anosmia

lack of sense of smell

apraxia

inability to perform purposeful movements or to use objects appropriately

dyslexia

inability or difficulty with reading and/or writing

cerebral palsy

abbr CP
motor function disorder as a result of permanent, nonprogressive brain defect or lesion caused perinatally
characterized by neural deficits such as ataxia

Huntington chorea

inherited disorder that manifests itself in adulthood as a progressive loss of neural control, uncontrollable jerking movements, and dementia.

hydrocephalus

condition of abnormal accumulation of fluid in the ventricles of the brain; may or may not result in mental retardation
usually diagnosed in babies, may occur in adults as a result of stroke, trauma, or infection

spina bifida

condition in which the spinal column has an abnormal opening that allows protrusion of the meninges and/or the spinal cord

meningocele

also meningomyelocele
protrusion of the meninges and/or the spinal cord

Tay-Sachs disease

inherited disease that occurs mainly in people of Eastern European Jewish origin
caused by an enzyme deficiency that results in CNS deterioration

coma

deep, prolonged unconsciousness from which the patient cannot be aroused
usually the result of a head injury, neurologic disease, acute hydrocephalus, intoxication, or metabolic abnormalities

concussion

serious head injury characterized by one or more of the following: loss of consciousness, amnesia, seizures, or a change in mental status

cerebral contusion

head injury of sufficient force to bruise the brain

hematoma

localized collection of blood, usually clotted, in an organ, tissue, or space, due to a break in the wall of a blood vessel

herniated intervertebral disk

abbr HIVD
a displacement of an intervertebral disk so that it presses on a nerve, causing pain and/or numbness

Alzheimer disease

abbr AD
progressive, neurodegenerative disease in which patients exhibit an impairment of cognitive functioning.
cause unknown
most common cause of dementia

amyotrophic lateral sclerosis

abbr ALS
degenerative, fatal disease of the motor neurons, in which patients exhibit progressive muscle weakness and atrophy
also Lou Gehrig disease

Guillain-Barre syndrome

autoimmune disorder of acute polyneuritis producing profound myasthenia that may lead to paralysis

multiple sclerosis

abbr MS
neurodegenerative disease characterized by destruction of the myelin sheaths on the CNS neurons and their abnormal replacement by the gradual accumulation of hardened plaques.
Disease may be progressive or characterized by remissions and relapses.

Parkinson disease

abbr PD
progressive neurodegenerative disease characterized by tremors, fasciculations, slow shuffling gait, hypokinesia, dysphasia, and dysphagia.

Bell palsy

paralysis of the facial nerve
unkown in cause, usually resolves on its own within 6 months

epilepsy

group of disorders characterized by some or all of the following: recurrent seizures, sensory disturbances, abnormal behavior, and/or loss of consciousness

narcolepsy

disorder characterized by sudden attacks of sleep

Tourette syndrome

abnormal condition characterized by facial grimaces, tics, involuntary arm and shoulder movements, and involuntary vocalizations, including corprolalia (use of vulgar, obscene, or sacrilegious language)

encephalitis

inflammation of the brain, most frequently caused by a virus transmitted by the bite of an infected mosquito

meningitis

any infection or inflammation of the membranes covering the brain and spinal cord, most commonly due to viral infection, although more severe strains are bacterial or fungal in nature

neuritis

inflammation of the nerves

polyneuritis

inflammation of several peripheral nerves

radiculitis

inflammation of the root of a spinal nerve
radicul/o = nerve root

sciatica

inflammation of the sciatic nerve
symptoms include pain and tenderness along the path of the nerve through the thigh and leg

shingles

acute infection caused by the latent varicella zoster virus (chicken pox), characterized by the development of vesicular skin eruption underlying the route of cranial or spinal nerves
also herpes zoster

cerebrovascular accident

abbr CVA
ischemia of cerebral tissue due to an occlusion from a thrombus or embolus, or as a result of a cerebral hemorrhage
also stroke, brain attack, and cerebral infarction

migraine

headache of vascular origin
may be classified as with or without aura

transient ischemic attack

abbr TIA
same mechanisms as CVA, but the sequelae resolve and disappear within 24 hours
also ministroke

diplegia

paralysis of the same body part on both sides of the body
di = two

hemiparesis

muscular weakness or slight paralysis on the left or right side of the body
-paresis = slight paralysis

hemiplegia

paralysis on the left or right side of the body

monoparesis

weakness or slight paralysis of one limb on the left or right side of the body

monoplegia

paralysis of one limb on the left or right side of the body

paraparesis

slight paralysis of the lower limbs and trunk

paraplegia

paralysis of the lower limbs and trunk

quadriparesis

weakness or slight paralysis of the arms, legs, and trunk

quadriplegia

paralysis of arms, legs, and trunk

meningioma

slow growing, usually benign tumor of the meninges
although benign, may cause problems because of their size and location

neurofibroma

benign fibrous tumors composed of nervous tissue

neuroma

benign tumor of the nerves

astrocytoma

tumor arising from star-shaped glial cells that is malignant in higher grades
grade IV is referred to as
glioblastoma multiforme
, the most common primary brain cancer

medulloblastoma

tumor arises from embryonic tissue in the cerebellum
most commonly seen in children

neuroblastoma

highly malignant tumor arising from either the autonomic nervous system or the adrenal medulla
usually affects children <10 years of age