Michele's NPTE review

Stroke volume

amt of blood ejected with each myocardial contraction

SV norm

55-100 mL/beat

LVEDV

left ventricular end diastolic volume=
amt of blood in LV at end of diastole (aka preload)

Frank Starling Law

the greater the diastolic filling (preload) the greater the amt of blood pumped

cardiac output

amt of blood discharged from LV or RV per minute

CO norm

4-5 L/min

LVEDP

left ventricular end diastolic pressure=
pressure in LV during diastole
5-12 mmHg

Ejection Fraction

percentage of blood emptied from ventricle during diastole, clinical measurement of LV fxn

EF norm

EF= SV/LVEDV
60-70%
lower EF -> impaired LV

Rate Pressure Product (myocardial oxygen demand)

energy cost to myocardium
RPP= HR x SBP

common adverse s/e of antiviral therapy

rash, nausea, HA, dizziness, mm pain, weakness, fatigue, difficulty sleeping (with hepatotoxicity signs of CTS can be seen)

composition of blood

55% plasma
45% RBC
1% WBC

complete blood count

(CBC), determines number of RBC, WBC, and platelets per unit blood

Erythrocyte sedimentation rate

(ESR), rate of RBCs that settle out in a tube of unclotted blood (mL/hour)
elevated ESR= presence of inflammation

c/i with sickle cell disease

COLD
it increased vasoconstriction and sickling

hemophilia precautions

PROM/stretching rarely used 2/2 risk of myositis ossifcans

red flags for hematological disorders

EXTREME caution with manual therapy and use of some modalities (ex: mechanical compression)
strenuous exercise is c/i 2/2 to risk of increased hemorrhage

red flags for anemia

pts have decreased EX tolerance, initiate EX gradually with MD approval, use RPE ratings

c/i for chronic fatigue syndrome (CFS)

bed rest is c/i other than for sleep

s/e of radiation for CA Tx

radiation sickness, immunosuppression, fibrosis, burns, delayed wound healing, edema, hair loss, CNS effects

s/e of chemotherapy for CA Tx

GI symptoms (n/v, anorexia, diarrhea, ulcers, hemorrhage), bone marrow suppression, skin rashes, neuropathies, phlebitis, hair loss

s/e of biotherapy (immunotherapy) for CA Tx

fever, chills, n/v, anorexia, fatigue, fluid retention

s/e of hormonal therapy for CA Tx

GI sxs, HTN, steroid-induced diabetes and myopathy, weight gain, hot flashes and sweating, altered mental status, impotence

CA red flags for PT exam: paraneoplastic syndrome

s/s at a site distance from the tumor or met, from etopic H production by tumor cells or metabolic abnormalities from secretion of tumor-vasoactive products

CA red flags for PT exam: Cushing's syndrome

can result from small cell cancers of the lung

CA red flags for PT exam: neuro sxs

cerebellar degeneration, peripheral neuropathy, myasthenia gravis

CA red flags for PT exam: sxs from CA stimulation of antibody production

anorexia, malaise, diarrhea, weight loss, fever, progressive mm weakness (type II atrophy), diminished DTRs, myositis, joint pain

red flags for pts with signficant bony mets, osteoporosis, or low platelet counts (< 20,000)

*
AROM, ADL EX ONLY
*
WB may be restricted (provide AD)
high risk of vertebral compression and other fx- light EX only

c/i for EX with low platelet count

<20,000 c/i
20,000-50, 000 pxn

referred pain for constipation

abdominal pain and tenderness in the anterior hip, groin or thigh regions

referred pain: esophagus->

mid back

referred pain: mid thoracic spine pain (nerve root) ->

esophagus

referred pain: gallbladder, stomach, pancreas, small intestine ->

mid back and scapular regions

referred pain: colon, appendix, or pelvic viscera ->

pelis, low back or sacrum

red flags for GERD

head and neck pain, chest pain (mistaken for MI, unrelated to activity), respitory sxs

c/i for the GERD

valsalva's maneuver

red flag for hiatal hernia

pts taking long term NSAIDS should be monitored closely for stomach pain, bleeding, n/v

referred pain: peptic ulcers on posterior wall of the stomach ->

radiating back pain, can also radiate to the right shoulder

red flags for IBD, referred pain: joints ->

low back

red flags for IBD

intestinal obstruction and corticosteroid toxicity (low bone density, increased fx risk), intestinal absorption disrupted (nutritional deficiencies), anxiety/depression

red flags for diverticular disease

pt may c/o back pain

red flags for appendicitis

need immediate medical attention when sxs present

sxs of appendicitis: Blumberg's sign

rebound tenderness present in response to depression of abdominal wall at site distant from pain area

sxs of appendicitis: McBurney's point

point tenderness over appendix, 1.5-2 inches above ASIS in RLQ

red flags for menopause

osteoporosis and risk fo bone fx dramatically increased, heart disease and stroke risk factors increase

postural changes with PG

kyphosis with scap retraction, cervical lordosis with forward head, lumbar lordosis (continues postpardum 2/2 carrying baby)

diastasis recti abdominis

lateral separation or split of the rectus abdominis
separation from lina alba >2cm is significant

diastasis recti abdominis pxns

avoid abdominal EX when >2cm
resume wth separation < 2cm (partial sit-ups, pelvic tilts); use hands to support abdominal wall

cystocele

herniation of bladder into vagina

rectocele

herniation of rectum into vagina

uterine prolapse

bulging of the uterus into the vagina

red flag for pelvic floor disorders

pain can radiate down the posterior thigh

preeclampsia

PG induced, acute HTN after 24 weeks
*
prompt MD referral
*

C-section Tx

TENS for incision pain (electrodes //to incision), assist breathing/coughing, gentle ab EX (pillow for bracing), pelvic floor EX, ambulation, friction massage for scar

precautions post C-section

no heavy lifting for 4-6 weeks

red flags for endometriosis

pt may c/o back pain, endometrial implants on mm (psoas major, pelvic floor) may produce pain with palpation

red flags for prsotatitis

dull, aching pain in lower abdominal, rectal, lower back, sacral or groin regions

glomerular filtration rate

(GFR), amt of filtrate that is formed each minute as blood moves thru the glomeruli
serves as important gauge of renal fxn

blood urea nitrogen

(BUN), urea produced in the liver as a by-product of protein metabolism that is eliminated by the kidneys

norm K level

3.5-5.5 mEq/L

sxs of hypokalemia

mm weakness, aches, fatigue, cardiac arrhythmias, abdominal distention, n/v

sxs of hyperkalemia

(often no sxs until very high levels)
mm weakness, arrhythmias, ECG changes (tall T wave, prolonged P-R interval and QRS duration)

norm Na levels

135-146 mEq/L

sxs of hyponatremia

confusion, decreased mental alertness can progress to convulsions, signs of increased intracerebral pressure, poor motor coordination, sleepiness, anorexia

sxs of hypernatremia

circulatory congestion (pitting edema, excessive wt gain), pulm. edema with dyspnea, HTN, tachycardia, agitation, restlessness, convulsions

norm Ca levels

8.4-10.4 mg/dL

sxs of hypocalcemia

mm cramps, tetany, spasms, parasthesias, anxiety, irritability, twitching convulsion, arrhythmias, hypotension

sxs of hypercalcemia

fatigues, depression, mental confusion, n/v, increased urination, occasional cardiac arrhythmia

norm level of Mg

1.8-2.4 mg/dL

sxs of hypomagnesemia

hyperirritability, confusion, leg and foot cramps

sxs of hypermagnesemia

hyporeflexia, mm weakness, drowsiness, lethargy, confusion, bradycardia, hypotension

sxs of metabolic acidosis

hyperventilation, deep respirations, weakness, muscular twiching, malaise, n/v, diarrhea, HA, dry skin & mucous membranes, poor skin turgor

metabolic acidosis

depletion of bases or an accumulation of acids

metabolic alkalosis

increase in bases or a reduction of acids

sxs of metabolic alkalosis

hypoventilation, depressed respirations, prolonged vomiting, diarrhea, weakness, mm twitching, irritability, agitation, convulsions, and coma (death)

causes of metabolic acidosis

DM, renal insufficiency or failure, diarrhea

causes of metabolic alkalosis

excess vomiting, excess diarrhea, hypokalemia, peptic ulcer, excessive intake of antacids

respiratory acidosis

CO2 retention
impaired alveolar ventilation

causes of respiratory acidosis

hypoventilation, drugs/oversedation, chronic pulm, disease, hypermetablism

sxs of respiratory acidosis

dyspnea, hyperventilation cyanosis, restlessness, HA

respiratory alkalosis

diminished CO2
alveolar hyperventilation

causes of respiratory alkalosis

anxiety attack with hyperventilation, hypoxia, impaired lung expansion, CHF, PE, diffuse liver or CNS disease, salicylate poisoning, extreme stress

sxs of respiratory alkalosis

tachypnea, dizziness, anxiety, difficulty concetrating, numbness/tingling, blurred vision, diaphoresis, mm cramps, twitching or tetany, weakness, arrhythmias, convulsions

dialysis shunt c/i

cannot take BP at shunt site

stress incontinence

sudden release of urine 2/2:
increases in intra-abdominal pressure
weakness/laxity of pelvic floor mm, sphincter weakness

urge incontinence

bladder begins contracting and urine is leaked after sensation of bladder fullness is perceived
inability to delay voiding (detrusor mm instability, sensory instability)

overflow incontinence

bladder continuously leaks 2/2 to urinary retention (atatomical obstrcution, acontractile bladder, neuroenic bladder)

functional incontinence

inability or unwillingness to toilet (impaired cognition, impaired physical fxning, environmental barriers)

historical research

investigation of a variety of data sources
investigates authenticity of data (external criticism)
investigates worth of the data (internal criticism)

descriptive research

involves collecting data about conditions, attitudes or characteristics of subjects, groups, or groups of subjects

case study

type of descriptive research; in-depth investigation of an individual, group or institution

developmental research

type of descriptive research; studies of behaviors that differentiate individuals at different levels of age, growth, maturation

longitudinal studies

type of descriptive research; differentiate changes in an individual or group over time

normative research

type of descriptive research; investigates standards of behavior, standard values for given characteristics of a sample (ex: gait characteristics)

qualitative research

type of descriptive research; seeks facts or causes of social phenomena, complex human behavior

correlational research

attempts to determine whether a relationship exists b/t two or more quantifiable variable and to what degree

retrospective

example of correlational research; investigation of data collection in the past

prospective

example of correlational research; recording and investigation of present data

descriptive

example of correlational research; investigation of several variables at once, determines existing relationships among variables

predictive

example of correlational research; use to develop predictive models

experimental research

attempts to define a cause and effect relationship thru group comparison

true experimental design

example of experimental research; includes random assignment into experimental group or control group

cohort design

example of experimental research; quasi-experimental design, subjects ID'd and followed over time for changes, lacks randomization

with-in subject design (repeated measures)

example of experimental research; subjects serve are their own controls, randomly assigned to Tx or no Tx blocks

between subject design

example of experimental research; comparison made b/t groups of subjects

single subject experimental design

involves a sample of one with repeated measurements and design phases

A-B design

example of single subject experimental design; involves 2 phases: baseline f/b Tx

A-B-A

single subject experimental design; aka multiple baseline design, involves 3 phases: baseline phase, Tx phase, 2nd baseline phase

A-B-A-B

single subject experimental design; aka multiple baseline multiple Tx, includes baseline, Tx and additional baseline and Tx phases

factorial design

refers to the number of independent variables utilized (ex: single factor)

causal- comparative research

attempts to define a cause-and-effect relationship thru group comparisons

epidemiology

the study of disease frequency and distribution in a community
the science concerned with examining and determining the specific causes of health problems and interrelationship of factors

independent variable

the cause or Tx, the factor believed to bring about a change in the dependent variable

dependent variable

the outcome being evaluated, the change or difference in the behavior that results from the intervention (Independent variable)

directional (research) hypothesis

generalization that predicts an expected relationship b/t variables

null hypothesis

states that no relationship exists b/t variables

reject null hypothesis

significant difference observed b/t groups or Tx

accept null hypothesis

no significant difference b/t groups or Tx

nominal data

classifies variables or scores into 2 or more mutually exclusive categories based on common characteristics; lowest level of measurement (ex: male/female, tall/short)

ordinal data

classifies variables by the degree to which they possess a common characteristic; intervals not equal (ex: MMT)

interval data

classifies variables based on predetermined equal intervals, does not have a true zero (ex: temperature)

ratio data

classifies variables basked on equal intervals and a true zero point, highest and most precise measurement (ex: goniometry, weight, height)

random selection

all individuals in a population have an equal chance of being chosen

systematic selection

individuals are selected from a population list at a specific interval (ex: every 10th)

stratified selection

individuals selected from a population from identified subgroups based on a predetermined characteristic (ex: height, weight, gender)

double-blind study

experiment in which subject and researcher are not aware of group assignment

effect size

the size of the difference b/t sample means
allows a statistical test to find difference when one does exist

generalizibility

degree to which a study's findings based on a sample apply to the entire population

gold standard

an instrument with established validity can be used as a standard for assessing another instrument

components of informed consent

information about the general nature of what is to take place, any risks to the individual and what will be done to minimize the risks, possible benefits, an ethical disclosure

control

researcher attempts to remove the influence of any variable other than the one being tested

control group

group that resembles the experimental group but who do not receive the different Tx

experimental group

group that receives a new or novel Tx that is under investigation

intervening variable

variable that alters the relationship b/t independent and dependent variable (ex: anxiety)

validity

the degree to which a test, instrument or procedure accurately measures with is supposed to or intended to measure

internal validity

degree to which the observed differences on the dependent variable are the direct result of manipulation of the independent variable

external validity

degree to which the results are generalizable to individuals or environmental settings outside of the experimental study

content validity

degree to which an instrument measures an intended content area

concurrent validity

degree to which the scores on one test are related to score on another criterion with both tests being given at relatively similar times (usually involves comparison to the gold standard)

predictive validity

degree to which a test is able to predict future performance

construct validity

degree to which a test measures an intended hypothetical abstract concept (non-observable behaviors or ideas)

sampling bias

threat to validity; selection bias, researcher introduces sampling error (ex:sample of convenience)

failure to exert rigid control over subjects and conditions

threat to validity; intervening variables interact with dependent variable

pretest treatment interaction

threat to validity; subjects respond differently to Tx b/c of the pretest

multiple Tx interference

threat to validity; more than once Tx is being given to the subjects at the same time or carryover effects from an earlier Tx influences results of a later Tx

experimenter bias

threat to validity; expectations of the researcher about the expected outcomes influence the results

Hawthorne effect

threat to validity; subject's knowledge of participation in an experiment influences the results of the study

placebo effect

threat to validity; subjects respond to a sham Tx with positive effects

reliability

degree to which a test consistently measures what it is intended to measure

test-retest reliability

degree to which the scores on a test are stable or consistent over time, measure of instrument stability

split-half reliability

degree of agreement when a test is split in half and the reliability of the first half compared to the second; internal consistency of an instrument

threats to reliability

errors of measurement, random/systematic errors

sensitivity

ability to correctly identify proportion of individuals who truly have a disease (true positive)

specificity

ability to correctly identify the proportion of individuals who do not have a disease (true negative)

predictive value

test's ability to estimate the likelihood that a person will test positive (or negative) for a target condition

true negative

individuals correctly identified as not having the target condition

true positive

individuals correctly identified as having the condition

false positive

individuals are identified as having the condition when they do not

false negative

individuals are identified as not having the condition when they do

systematic review (meta-analysis)

review in which the primary studies are summarized, critically appraised, and statistically combines, usually quantitative in nature with specific inclusion/exclusion criteria

randomized control trial

experimental study in which participants are randomly assigned to either experimental or control group to receive different interventions or a pacebo

cohort study

prospective, group of participants with similar condition followed for a defined period of time, comparison made to a group w/o condition

homogeneity

SR free of variation

case-control study

retrospective, group with similar conditions compared to a group w/o, to determine factors that played a role in the condition

case report

descriptive research, only one individual is studied in depth, often retrospective

evidence level 1a

SR (w/ homogeneity), multiple RCTs, randomization of large numbers of pts, multicenter, substantial agreement of size and direction of Tx effects

evidence level 1b

individual RCT with narrow confidence level, Tx effects precisely defined

evidence level 1c

all or none case series, in absence of RCT overwhelming evidence of substantial Tx effect following introduction of a new Tx (ex: vaccine)

evidence level 2a

SR (with homogeneity) or cohort studies (comparison groups); prospective: pts are ID'd for study b/4 outcomes achieved

evidence level 2b

individual cohort study or low quality RCT (small N), quality study includes more than 80% f/u of pts enrolled in study

evidence level 3a

SR (with homogeneity) of case-controlled studies (case comparison)

evidence level 3b

individual case control study, retrospective: pts ID'd for study after outcomes achieved

evidence level 4

case-series and poor-quality cohort and case-control studies, largely descriptive studies

evidence level 5

expert opinion w/o explicit critical appraisal, or based on physiology, bench research or first principles
observations not made on pts

mean

average of all the scores, used with interval or ratio data

median

midpoint, used with ordinal data

mode

most frequently occurring score, used with nominal data

standard deviation

determination of variability of scores from the mean, most frequently used measure of variability; used with interval or ratio data

tests of significance

estimation of true differences, not due to chance; rejection of the null hypothesis

alpha level

preselected level of statistical significance, allows rejection of the null, often expressed as a value of P

standard error

expected chance variation among the means, the result of sampling error

type I error

null hypothesis is rejected with it is true (i.e. scores concluded to be significantly different when the difference is really due to chance)

type II error

null hypothesis not rejected when it is false (i.e. scores concluded to be due to chance when they are actually statistically significant)

t-test

parametric test of significance used to compare two independent groups created by random assignment and identify a difference at a selected probability level

t-test for independent samples

compares difference b/t 2 independent groups (ex: if a splint improves fxn in pts with RA)

t-test with paired samples

compares the difference b/t 2 matched samples (ex: does therapy improve fxn in siblings with autism)

one tailed t-test

based on directional hypothesis, evaluates data on one end of the distribution, positive or negative (ex: pts who receive an Rx will have a better rehab outcome than those that do not)

two tailed t-test

based on non-directional hypothesis, evals data on both positive and negative ends of distribution, *
tests of significance are almost always 2 tailed
* (ex: either group, Tx or control, may exhibit better rehab outcomes)

analysis of variance

ANOVA
parametric test used to compare 3 or more independent Tx groups or conditons

one-way (simple) ANOVA

compares multiple groups on a single indep. variable

multifactorial ANOVA

compares multiple groups on two or more indep. variables

analysis of covariance

ANCOVA
parametric test used to compare two or more treatment conditions while also controlling for the effects of the intervening variables

chi square test

non-parametric test of significance used to compare data in the form of frequency counts occurring in two or more mutually exclusive categories

correlational statistics

used to determine the relative strength of a relationship b/t 2 variables

pearson product-moment coefficient (r)

used to correlate continuous data with underlying normal distribution on interval or ratio scales

spearman's rank correlation coefficient

non-parametric test used to correlate ordinal data

point biserial correlation

one variable is dichotomous (nominal) and the other is a ratio or interval (ex: relationship between elbow flexor spasticity and side of stroke)

rank biserial correlation

one variable is dichotomous (nominal) and the other is ordinal (ex: relationship b/t gender and fxnal ability)

intraclass correlation coefficient

ICC
reliability coefficient based on analysis of variance

high correlation

>0.76 to 1.0

moderate correlations

0.51 to 0.75

fair correlation

0.26 to 0.50

low correlation

0.0 to 0.25

common variance

representation of the degree that variation in one variable is attributable to another variable, determine by squaring the correlation coefficient

linear regression

used to establish the relationship b/t two variables as a basis for prediction; purpose is to generate an equation which relates X to Y

tidal volume

TV
volume of gas inhaled (or exhaled) during nL resting breath

inspiratory reserve volume

IRV
volume of gas that can be inhaled beyond a nL resting tidal inhalation

expiratory reserve volume

ERV
volume of gas that can be exhaled beyond a nL resting tidal exhalation

residual volume

RV
volume of gas that remains in the lungs after ERV has been exhaled

capacities

two or more lung volumes added together

inpiratory capacity

IRV + TV
amt of air that can be inhaled from REEP

resting end expiratory pressure

REEP
point of equilibrium where forces acting on the rib cage are balanced, occurs at end tidal expiration

vial capacity

IRV + TV +ERV
amt of air that is under volitional controls, measured as forced expiratory vital capacity (FVC)

functional residual capacity

ERV + RV
amt of air that resides in the lungs after a nL resting tidal exhalation

total lung capacity

IRV + TV +ERV + RV
total amt of air contained within the thorax during maximum inspiratory effort

forced expiratory volume in 1 second

FEV1
amt of air exhaled during 1st second of FVC

FEV1 norms

at least 70% of FVC
FEV1/FVC * 100> 70%

forced expiratory flow rate

FEF 25%-75%
slope of the line drawn b/t 25% and 75% of exhaled volume on a FVC exhalation curve; more specific to smaller a/w

partial pressure of O2 in atmosphere

PaO2= 159.6 mmHg

partial pressure of O2 in arterial blood

PaO2= 95-100 mmHg

fraction of O2 in inspired air

FiO2= 21%

pH norms

7.35 - 7.45

PaCO2 norms

35 mmHg - 45 mmHg
inversely proportional to pH

hypercapnea

PaCO2 > 45 mmHg

hypocapnea

PaCO2 < 35 mmHg

bicarbonate norms

22 - 28 mEq/mL
proportional to pH

dead space

space that is well-ventilated but no respiration (gas exhange) occurs
pathological ex: PE

shunt

no respiration occurs b/c of a ventilation abnormality

heart rate adult

60-100 bpm

heart rate infant

120 bpm

blood pressure adult

<120/80 mmHg

blood pressure infant

75/50 mmHg

resp rate adult

12-20 breaths/min

resp rate infant

40 breaths/min

PaO2 infant

75-80 mmHg

tidal volume adult

500 mL

tidal volume infant

20mL

crackles

(rales, crepitations)
crackling sound heard usually during inspiration that indicated pathology (atelectasis, fibrosis, pulm. edema)

wheezes

musically pitched sound, usually heard during expiration, cause by a/w obstruction (asthma, COPD, foreign body aspiration)

signs of respiratory acidosis

early: anxiety, restlessness, dyspnea, HA
late: confusion, somnolence, coma

signs of respiratory alkalosis

dizziness, syncope, tingling, numbness, early tetany

signs of metabolic acidosis

secondary hyperventilation (Kussmaul breathing), nausea, lethargy, coma

signs of metabolic alkalosis

vague sxs: weakness, mental dullness, possibly early tetany

WBC norm

4,300 to 10,800
*
<5,000 with fever EX is C/i
*
<1, 000 use mask

hematocrit norm

35% to 48%

hemoglobin norms

12 to 16 g/dL

COPD stage 1 (mild)

FEV1/FVC <70%
FEV1 >= 80% predicted
with or without chronic sxs

COPD stage 2 (moderate)

FEV1/FVC <70%
50 % < FEV1 < 80% predicted
often with SOB on exertion

COPD stage 3 (severe)

FEV1/FVC <70%
FEV1 < 30% predicted
increasing SOB, decreased EX capacity, exacerbations of disease

COPD stage 4 (very severe)

FEV1/FVC <70%
FEV1 < 30% predicted
FEV1 < 50% with chronic resp. failure sxs
impaired QOL
exacerbations of disease may be life threatening

ABI 1.0 or higher

nL
ankle systolic P is at least as high as brachial P

ABI 0.8 to 1.0

mild PAD
compression Tx with caution

ABI 0.5 to 0.8

moderate PAD
compression Tx C/i

ABI <0.5

severe arterial disease, critical limb ischemia, + for resting pain
compression Tx C/i

dyspnea +1

mild
noticable to pt but not to observer

dyspnea +2

mild
some difficulty, noticeable to observer

dyspnea +3

moderate difficulty but can continue

dyspnea +4

severe difficulty, pt cannot conitnue

anginal scale 1+

light, barely noticable

anginal scale 2+

moderate, bothersome

anginal scale 3+

severe, very uncomfortable

anginal scale 4+

most severe pain ever experienced

edema 1+

mild, barely perceptible to indentation
0 to 1/4" pitting

edema 2+

moderate, easily identified depression, returns to nL within 15 sec
1/4 to 1/2" pitting

edema 3+

severe, depression takes 15-30 seconds to rebound
1/2 to 1" pitting

edema 4+

very severe, depression lasts for 30 seconds or more
>1" pitting

SpO2 norm

95% - 100%

prothrombin time (PT)

11 - 15 sec
*
if <2.5x norm PT C/i
*

partial prothrombin time (PTT)

25 - 40 sec

international normalized ratio (INR)

0.9 - 1.1

bleeding time

2 - 10 min

red blood cells (RBC)

male 4.6 - 6.2 10^6/uL
female 4.2 - 5.9 10^6/uL

erythrocyte sedimentation rate (ESR)

male: up to 15 mm/hr
female: up to 20 mm/hr

hematocrit (Hct)

male: 45 - 52%
female: 37 - 48%
*
<25% EX is C/i
*

hemoglobin

male: 13-18
female: 12-16
*
<8 EX is C/i
*

platelet count

150,000 - 450,000 cells/mm^3

fibrinogen, plasma

175 - 433 mg/dL

S1 sound

lub"
nL closure of the mitral and tricuspic valves, beginning of systole

S2 sound

dub"
nL closure of aortic and pulmonary valves, end of systole

S3 sound

abnL
associated with CHF

S4 sound

abnL
associated with MI or chronic HTN

P wave

atrial depolarization

QRS wave

ventricular depolarization

ST segment

beginning of ventricular repolarization

T wave

ventricular repolarization

PVC

premature ventricular contractions
during EX: serious when more than 3-5 in a row per minute, multifocal

ventricular tachycardia

run of 3 or more PVCs in a row
wide QRS
no P wave

ventricular fibrillation

chaotic activity of ventricle from multiple foci
unable to determine HR
erratic, without QRS

ST depression

may indicate ischemia if downsloping 2-3mm

ST elevation

new infarct or pericarditis

inverted T wave

ischemia

wide QRS

occurs with bundle branch heart blocks
slowed ventricular rate, dec CO
*
3rd degree block= life threatening, need atropine
*

SaO2 cutoff for supplemental O2

88%

EX guidelines for phase 1 cardiac rehab

acute stage (<1 wk for uncomplicated MI)
initially 2-3 METS, progress to 3-5 METS
short bouts, 2-3x/day

EX guidelines for phase 2 cardiac rehab

subacute (home or OP; 1-2 wks post MI)
3-4x/week
30-60 min with 5-10 min warm up/cool down
d/c at 9 METS

EX guidelines for phase 3 cardiac rehab

post-acute, community EX (3-6 months post MI)
must fxn at 5 METS to start
progress from supervised -> indep. EX
progress to 50-80% fxnal capacity
3-4x/week
45+ min/session

signs that pt needs further diagnostic eval for cardiac rehab

sxs: fatigue, lightheaded, confusion, ataxia, pallor, cyanosis, dysnpea, nausea, onset of angina
st displacement (2mm) horizontal or downsloping from rest
v-tach
3+ consecutive PVCs
dec SBP more 20 mmHg
inc SBP >220 DBP> 110