CHAPTER 3 CELLULAR LEVEL OF ORGANIZATION

3 MAIN PARTS OF A CELL

1.nucleus
2.plasma membrane
3.cytoplasm

NUCLEUS

large organelle that houses most of a cell's dna

CHROMOSOME

a single molecule of DNA associated with several proteins,contains thousands of hereditary units

GENES

thousands of hereditary units. controlls most aspects of cellular structure and function

PLASMA MEMBRANE

forms the cell's flexible outer surface, separating the cell's internal environment fromm the external environment. it is a selective barrier that regualtes the flow of materials into and out of a cell. plays a key role in communication among cells and be

CYTOPLASM

consists of all the cellular contents between the plasma membrane and the nucleus.l this compartment has two components: cytosol and organelles.

CYTOSOL

fluid portion of cytoplasm, contains water, dissolved solutes, anbd suspended particles.

ORGANELLES

has a specific shape and specific function

NUCLEUS

large organelle that houses most of a cell's DNA.

STRUCTURE OF PLASMA MEMBRANE:

the basic structural framework of the plasma membrane is the lipid bilayer. two back to back layers made up of three types of lipid molecules-phospholipids,cholesterol and glycolipids. about 75% of the membrane lipids are phospholipids, lipids that contai

AMPHIPATHIC

both polar and nonpolar parts

ROLE OF PHOSPHOLIPIDS:

water loving the head (blue) face a watery fluid on either side

PLASMA MEMBRANE:

flexible but sturdy structure that surrounds the cytoplasm.
membrane is 50% lipid, 50% protein
lipid is barrier to entry and exit of polar substances
proteins are "gatekeepers" regulate traffic
50 lipid molecules for every protein molecule

LIPID BILAYER MADE UP OF THREE PARTS:

phospholipids,cholesterol, and glycolipids

GLYCOLIPIDS

carbohydrate group form a polar head that appears only in the membrane layer which faces which faces the extracellular fluid

CHOLESTEROL

is weakly amphiphotic and are interspersed among other lipids

PHOSPHOLIPDS

comprise 75% of lipids

PHOSPHOLIPID BILAYER

2 parralel layers of molecules, each molecule is amphipathic, (has both a polar and nonpolar region), polar parts are hdrophyllic, nonpolar parts are hydrophobic

CHOLESTEROL

comprises 20% of cell membrane fluid,interspersed among the other lipids in both layers,stiff steroid rings and hydrocarbon tail are nonpolar and hide in middle of cell membrane

INTEGRAL PROTEINS

extend or cross the entire lipid bilayer among the fatty acid tails of the phospholipid molecules.CAN'T LIVE WITHOUT THEM. EMBEDDED.

PERIPERAL PROTEINS

found at the inner and outer surface of the membrane and can be stripped away from the membrane without disturbing membrane integrity.COULD LIVE WITHOUT THEM. transports substances in and out of cells.hangs out on edge of surfaces.

FUNCTIONS OF MEMBRANE PROTEINS:

formation of channel, transports protien,receptor proteins,cell identity marker,linker, anchors protein in cell membrane or to other cells, allow cell movement, helps maintain cell shape and structure and membrane proteins act as enzyme and speed up react

MEMBRANE FLUIDITY

is a fluid structure, rather like cooking oil, because most of the membrane lipids and many of the membrane proteins easily move in the bilayer. membrane lipids and proteins are mobile in their own half of the bilayer.

CHOLESTEROL IN MEMBRANE FLUIDITY

serves to stabilize the membrane and reduce membrane fluidity.

SELECTIVE PERMEABILITY

the property of a membrane by which it permits the passage of certain substaqnces but restricts the passage of others.

HOW IS THE PLASMA MEMBRANE SELECTIVELY PERMIABLE?

*the lipid bilayer protion of the membrane is permeable to small, nonpolar, uncharged molecules but impermeable to ions and charged or polar molecules.
*the membrane is permiable to water
*transmembrane proteins act as channels or transporters increase pe

MACROMOLECULES

unable to pass through the plasma membrane except by vesicular transport.

CONCENTRATION GRADIENT

is the difference in the concentration of a chemical between one side of the plasma membrane and the other.

WHAT ELEMENT IS MORE CONCENTRATED OUTSIDE THE PLASMA MEMBRANE?

oxygen and sodium ions outside the cell membrane

WHAT ELEMENTS ARE MORE CONCENTRATED IN THE PLASMA MEMBRANE?

carbon dioxide and potassium ions

ELECTRICAL GRADIENT

inner surface of the plasma membrane is more negatively charged and outside is more positively charged , this is the difference in electrical charges between two regions.

HOW DO CONCENTRATION AND ELECTRICAL GRADIENTS AFFECT THE PERMEABILITY OF A PLASMA MEMBRANE?

they help move substances across the plasma membrane. in many cases a substance will move across a plasma membrane down its concentration gradient . it will move from more concentrated to less to reach equillibrium. negative charge will move to a positive

IMPORTANCE OF ELECTRICAL AND GRADIENT CONCENTRATIONS:

important to cell life.

ELECTROCHEMICAL GRADIENT

combined concentration and electrical gradients

TRANSPORT ACRSS THE PLASMA MEMBRANE CONSISTS OF:

1.mediated transport
2. nonmediated transport
3.active transport
4.passive transport
5.vesicular transport

MEDIATED TRANSPORT

moves material with the help of a tranporter protein (need assistance)

NONMEDIATED TRANSPORT

does not use a transporter protein (diffusion)

ACTIVE TRANSPORT

uses ATP to drive substances against their concentration gradients

PASSIVE TRANSPORT

moves substances down thier concentration gradient with only their kinetic energy (using thier own energy)

VESICULAR TRANSPORT

move materials across membranes in small vesicles--either by exocytosis or endocytosis.

OSMOSIS

net movement of a solvent through a selectively permeable membrane, or in living systems, the movement of water (the solute) from an area of higher concentration to an area of lower concentration across the membrane. passive process

HOW DO CELLS USE THE OSMOSIS PROCESS?

osmosis is the movement of water molecules through a selectively permeable membrane. want equilibrium in cells.

TONICITY

measure of a solutions ability to change the volume of cells by altering their water concentration

ISOTONIC SOLUTION

red blood cells maintian their normal shape

HYPOTONIC

red blood cells undergo hemolysis. too much water and the cell can burst

HYPERTONIC

red blood cells undergo crenation. water leaves the cell

PRIMARY ACTIVE TRANSPORT

most prevalent transport mechanism. uses ATP and and energy obtained through hydrolisis

SODIUM ION/ POTASSIUM ION PUMP

all cells have thousands of sodium-patassium pumps in thier plasma membrane. maintain a low concentration of Na+ in the cytosol by pumping them into the extracellular fluid against the Na+ concentration gradient. at the same time, the pump moves K+ into c

SECONDARY ACTIVE TRANSPORT

energy stored in Na+ or H+ concentration gradient is used to drive other substanfes across the membrane against their own concentration gradients. one way street

SYMPORTERS

transports two substances in the same direction. they can do their job because the Na+/K+ pump does its job

ANTIPOERTERS

move two substances in oposite directions across the membrane. two way street. can transport because the Na+/K+ pump does its job

VESICULAR TRANSPORT OF PARTICLES

1. endocytosis
2.exoctytosis

ENDOCYTOSIS

materials move into a cell in a vesicle formed from the plasma membrane. requires ATP

EXOCYTOSIS

materials move out of a cell by the fusion with the plasma membrane of vesicles formed inside the cell. requires ATP. vesicles from inside cell, fuse to cell membrane and release their content. release digbestive enzymes, hormones, neurotransmitters or wa

PHAGOCYTOSIS (endocytosis)

cell eating by macrophages and WBC's. particles binds to receptor proetins or whole bacteria or virus are englufed and later digested

CYTOSOL

inracellular fluid, the fluid portion of the cytoplasm that surrounds organelles and constitutes about % of total cell volume. contains inclusions and dissolved solutes. compsed mostly of water , plus proetins ,carbohydrates, lipids, and inorganic substan

ORGANELLE

specialized structures within the cell that have characteristic shapes, they perform specific functions in cellular growth, maintenance, and reproudction.

CYTOSOL FUNCTION

is the medium in which many metabolic reaction occurs.

CYTOSKELETON

network of protein filaments that extends throughout the cytosol. Filaments throught the cytosol.

FUNCTION OF CYTOSKELETON

cell support and shape, organization of chemical reaciotn, cell and organelle movement, and continuall reorganize

CENTROSOME

located near the nucleus. tubulin complexes are the organizing centers for growth of the mitotic spinds,which plays a critical roll in cell divison.

CILLIA (short) AND FLAGELLA (much longer)

microtubules are the dominant component of this and have motile projections of the cell surface.

MICROVILLI

take in nutrient, on surface to increase surface area for absorption. finger-like structures that expand surface area ex: cilia, flagella

RIBOSOMES

are tind spheres consisting of ribosomal rna nad several ribosomal proteins

RIBOSOME FUNCTION:

site of protein synthesis. made in the nucleolus, once produces, the large and small subunits exit the nucleus seperately then come together in the cytoplasm

ENDOPLASMIC RETICULUM

network of membranes. transports, synthesizes, packages, and stores proteins. detoxifies chemicals and releases calcium inon involved in muscle contraction.

ROUGH ER

studded with ribosomes. about proteins

SMOOTH ER

does not contain ribosomes on its membrane surface. detoxifying

GOLGI COMPLEX

UPS MAN.. sort and transport. main function is to process, sort,a nd deliver proteins and lipids to the plasma membrane, lysosomes, and secretory vesicles.

LYSOSOMES

stomach of the cell. low ph very acidic. membrane enclosed besicle that contains powerful digestive enzymes. internal ph reaches 5.0 function includes digestin substancves and recycling organelles.

PERIOXOSOMES

are similar in structure to lysosomes, but are smaller. they contain enzymes that oxidases enzymes that can oxidize (remove hydrogen atoms from..) varous organic substances. for instance, amino acids and fatty acids are oxsidized in this as part of normal

PROTEOSOMES

destroy uneeded, damaged, or faulty proteins. they contain proteases which cut proteins into small peptides. thought to be a foctor in several diseases.

MITOCHONDRIA

POWERHOUSE..bound by double membrane. the outer membrane is smooth, the inner membrane arranged in folds called cristae. this allows for increased surface area for chemical rections of cellular respiration.

SITE OF ATP PRODUCTION BY A CELL:

mitochondria

MITOCHONDRIA

self replicate using thier own dna.

NUCLEUS (director)

most prominent feature of a cell. within the nucleus are the cell's hereditary untis, called genes, which are arranged in single file along chromosomes.

NUCLEAR ENVELOPE

seperates the nucelus from the cytoplasm. both layers of the envelope are lipid bilayers

PARTS OF A NUCLEUS:

nuclear envelope which is perforated by channels called nuclear pores, nucleoli, and genetic material (DNA)

JOB OF NUCELUS:

nuclear pores control the movement of substances between the nucleus and cytoplasm, nucleoli produce robosomes and chromosomes consist of genes that control cellular structure and direct cellular functions.

PROTEIN SYNTHESIS

much of the cellular machinery is devoted to synthesizing large numbers of diverse proteins. the proteins determine the physical and chemical characteristics of cells. the instructions for protein synthesis is found in the dna in the nucleus. protein syth

TRANSCRIPTION

RNA= outside nucleus DNA= inside nucleus. process by which genetic information encoded in DNA is copied onto a strand of RNA called messenger RNA (mRNA), which directs protein synthesis. mRNA takes information outside the cell.

TRANSLATION

reading the mRNA nucleotide sequence to determine the amino acid sequence of the proetien. mRNA has information written in Spanish and need to write to english.

MITOSIS (everything else)

orderly division of the nucleus of a cell that ensures that each new nucleus has the same number and kind of chromosomes as the original nucleus.the process includes the replication of chormosomes and the distribution of the two sets of chromosomes into t

MEIOSIS (gammets)

a type of cell division that occurs during production of gametes, involving two successive nuclear division that result in cells with the haploid (n) number of chromosomes.

CYTOKINESIS

distribution of the cytoplasm into two seperate cells during cell divison, coordinated with nuclear divison (mitosis)

MITOSIS

splits into two cells. ends with cytokinesis

MEIOSIS

splits into four cells and has a stage one and two

CELL DIVISION

1.prophase
2.metaphase
3.anaphase
4.telaphase

PROPHASE

chromatin fibers condense and shorten into chromosomes that are visible under the light mjicroscope.

METAPHASE

microtubles of the mitotic spindle align the centromeres of the chromatid pairs at the exact center of the mitotic spinde.

ANAPHASE

centromeres split, sepataing the two members of each chromatid pair, which move toward opposite poles of the cell

TELOPHASE

final stages of mitosis, telophase, begins after chromosomal movement stops.

WHEN DOES CYTOKYNESIS BEGIN?

late anaphase with the formation of a cleavage furrow, a slight indentation of the plasma membrane, and is completed after telphase.

TELOMERS AND AGING CELLS

specific DNA sequence found only at the tips of each chromosome. these pieces of DNA protect th etips of chromosomes from erosion and from stricking to one another. after many cycles of cell division they can be comepletely gone and even some of the funct

FREE RADICALS AND AGING CELLS

roduce oxidative damage in lipids, proteins or nucleic acids by "stealing" an electron to accompany their unpaired electrons.

CELL IDENTITY MARKER CHANGES IN AGING CELLS:

the immune system may start to attack the body's own cells.as changes in the proteins on the plasma membrane of cells increase, the autoimmune response intensifies, producing the well known signs of aging.

3 MAIN PARTS OF A CELL

1.nucleus
2.plasma membrane
3.cytoplasm

NUCLEUS

large organelle that houses most of a cell's dna

CHROMOSOME

a single molecule of DNA associated with several proteins,contains thousands of hereditary units

GENES

thousands of hereditary units. controlls most aspects of cellular structure and function

PLASMA MEMBRANE

forms the cell's flexible outer surface, separating the cell's internal environment fromm the external environment. it is a selective barrier that regualtes the flow of materials into and out of a cell. plays a key role in communication among cells and be

CYTOPLASM

consists of all the cellular contents between the plasma membrane and the nucleus.l this compartment has two components: cytosol and organelles.

CYTOSOL

fluid portion of cytoplasm, contains water, dissolved solutes, anbd suspended particles.

ORGANELLES

has a specific shape and specific function

NUCLEUS

large organelle that houses most of a cell's DNA.

STRUCTURE OF PLASMA MEMBRANE:

the basic structural framework of the plasma membrane is the lipid bilayer. two back to back layers made up of three types of lipid molecules-phospholipids,cholesterol and glycolipids. about 75% of the membrane lipids are phospholipids, lipids that contai

AMPHIPATHIC

both polar and nonpolar parts

ROLE OF PHOSPHOLIPIDS:

water loving the head (blue) face a watery fluid on either side

PLASMA MEMBRANE:

flexible but sturdy structure that surrounds the cytoplasm.
membrane is 50% lipid, 50% protein
lipid is barrier to entry and exit of polar substances
proteins are "gatekeepers" regulate traffic
50 lipid molecules for every protein molecule

LIPID BILAYER MADE UP OF THREE PARTS:

phospholipids,cholesterol, and glycolipids

GLYCOLIPIDS

carbohydrate group form a polar head that appears only in the membrane layer which faces which faces the extracellular fluid

CHOLESTEROL

is weakly amphiphotic and are interspersed among other lipids

PHOSPHOLIPDS

comprise 75% of lipids

PHOSPHOLIPID BILAYER

2 parralel layers of molecules, each molecule is amphipathic, (has both a polar and nonpolar region), polar parts are hdrophyllic, nonpolar parts are hydrophobic

CHOLESTEROL

comprises 20% of cell membrane fluid,interspersed among the other lipids in both layers,stiff steroid rings and hydrocarbon tail are nonpolar and hide in middle of cell membrane

INTEGRAL PROTEINS

extend or cross the entire lipid bilayer among the fatty acid tails of the phospholipid molecules.CAN'T LIVE WITHOUT THEM. EMBEDDED.

PERIPERAL PROTEINS

found at the inner and outer surface of the membrane and can be stripped away from the membrane without disturbing membrane integrity.COULD LIVE WITHOUT THEM. transports substances in and out of cells.hangs out on edge of surfaces.

FUNCTIONS OF MEMBRANE PROTEINS:

formation of channel, transports protien,receptor proteins,cell identity marker,linker, anchors protein in cell membrane or to other cells, allow cell movement, helps maintain cell shape and structure and membrane proteins act as enzyme and speed up react

MEMBRANE FLUIDITY

is a fluid structure, rather like cooking oil, because most of the membrane lipids and many of the membrane proteins easily move in the bilayer. membrane lipids and proteins are mobile in their own half of the bilayer.

CHOLESTEROL IN MEMBRANE FLUIDITY

serves to stabilize the membrane and reduce membrane fluidity.

SELECTIVE PERMEABILITY

the property of a membrane by which it permits the passage of certain substaqnces but restricts the passage of others.

HOW IS THE PLASMA MEMBRANE SELECTIVELY PERMIABLE?

*the lipid bilayer protion of the membrane is permeable to small, nonpolar, uncharged molecules but impermeable to ions and charged or polar molecules.
*the membrane is permiable to water
*transmembrane proteins act as channels or transporters increase pe

MACROMOLECULES

unable to pass through the plasma membrane except by vesicular transport.

CONCENTRATION GRADIENT

is the difference in the concentration of a chemical between one side of the plasma membrane and the other.

WHAT ELEMENT IS MORE CONCENTRATED OUTSIDE THE PLASMA MEMBRANE?

oxygen and sodium ions outside the cell membrane

WHAT ELEMENTS ARE MORE CONCENTRATED IN THE PLASMA MEMBRANE?

carbon dioxide and potassium ions

ELECTRICAL GRADIENT

inner surface of the plasma membrane is more negatively charged and outside is more positively charged , this is the difference in electrical charges between two regions.

HOW DO CONCENTRATION AND ELECTRICAL GRADIENTS AFFECT THE PERMEABILITY OF A PLASMA MEMBRANE?

they help move substances across the plasma membrane. in many cases a substance will move across a plasma membrane down its concentration gradient . it will move from more concentrated to less to reach equillibrium. negative charge will move to a positive

IMPORTANCE OF ELECTRICAL AND GRADIENT CONCENTRATIONS:

important to cell life.

ELECTROCHEMICAL GRADIENT

combined concentration and electrical gradients

TRANSPORT ACRSS THE PLASMA MEMBRANE CONSISTS OF:

1.mediated transport
2. nonmediated transport
3.active transport
4.passive transport
5.vesicular transport

MEDIATED TRANSPORT

moves material with the help of a tranporter protein (need assistance)

NONMEDIATED TRANSPORT

does not use a transporter protein (diffusion)

ACTIVE TRANSPORT

uses ATP to drive substances against their concentration gradients

PASSIVE TRANSPORT

moves substances down thier concentration gradient with only their kinetic energy (using thier own energy)

VESICULAR TRANSPORT

move materials across membranes in small vesicles--either by exocytosis or endocytosis.

OSMOSIS

net movement of a solvent through a selectively permeable membrane, or in living systems, the movement of water (the solute) from an area of higher concentration to an area of lower concentration across the membrane. passive process

HOW DO CELLS USE THE OSMOSIS PROCESS?

osmosis is the movement of water molecules through a selectively permeable membrane. want equilibrium in cells.

TONICITY

measure of a solutions ability to change the volume of cells by altering their water concentration

ISOTONIC SOLUTION

red blood cells maintian their normal shape

HYPOTONIC

red blood cells undergo hemolysis. too much water and the cell can burst

HYPERTONIC

red blood cells undergo crenation. water leaves the cell

PRIMARY ACTIVE TRANSPORT

most prevalent transport mechanism. uses ATP and and energy obtained through hydrolisis

SODIUM ION/ POTASSIUM ION PUMP

all cells have thousands of sodium-patassium pumps in thier plasma membrane. maintain a low concentration of Na+ in the cytosol by pumping them into the extracellular fluid against the Na+ concentration gradient. at the same time, the pump moves K+ into c

SECONDARY ACTIVE TRANSPORT

energy stored in Na+ or H+ concentration gradient is used to drive other substanfes across the membrane against their own concentration gradients. one way street

SYMPORTERS

transports two substances in the same direction. they can do their job because the Na+/K+ pump does its job

ANTIPOERTERS

move two substances in oposite directions across the membrane. two way street. can transport because the Na+/K+ pump does its job

VESICULAR TRANSPORT OF PARTICLES

1. endocytosis
2.exoctytosis

ENDOCYTOSIS

materials move into a cell in a vesicle formed from the plasma membrane. requires ATP

EXOCYTOSIS

materials move out of a cell by the fusion with the plasma membrane of vesicles formed inside the cell. requires ATP. vesicles from inside cell, fuse to cell membrane and release their content. release digbestive enzymes, hormones, neurotransmitters or wa

PHAGOCYTOSIS (endocytosis)

cell eating by macrophages and WBC's. particles binds to receptor proetins or whole bacteria or virus are englufed and later digested

CYTOSOL

inracellular fluid, the fluid portion of the cytoplasm that surrounds organelles and constitutes about % of total cell volume. contains inclusions and dissolved solutes. compsed mostly of water , plus proetins ,carbohydrates, lipids, and inorganic substan

ORGANELLE

specialized structures within the cell that have characteristic shapes, they perform specific functions in cellular growth, maintenance, and reproudction.

CYTOSOL FUNCTION

is the medium in which many metabolic reaction occurs.

CYTOSKELETON

network of protein filaments that extends throughout the cytosol. Filaments throught the cytosol.

FUNCTION OF CYTOSKELETON

cell support and shape, organization of chemical reaciotn, cell and organelle movement, and continuall reorganize

CENTROSOME

located near the nucleus. tubulin complexes are the organizing centers for growth of the mitotic spinds,which plays a critical roll in cell divison.

CILLIA (short) AND FLAGELLA (much longer)

microtubules are the dominant component of this and have motile projections of the cell surface.

MICROVILLI

take in nutrient, on surface to increase surface area for absorption. finger-like structures that expand surface area ex: cilia, flagella

RIBOSOMES

are tind spheres consisting of ribosomal rna nad several ribosomal proteins

RIBOSOME FUNCTION:

site of protein synthesis. made in the nucleolus, once produces, the large and small subunits exit the nucleus seperately then come together in the cytoplasm

ENDOPLASMIC RETICULUM

network of membranes. transports, synthesizes, packages, and stores proteins. detoxifies chemicals and releases calcium inon involved in muscle contraction.

ROUGH ER

studded with ribosomes. about proteins

SMOOTH ER

does not contain ribosomes on its membrane surface. detoxifying

GOLGI COMPLEX

UPS MAN.. sort and transport. main function is to process, sort,a nd deliver proteins and lipids to the plasma membrane, lysosomes, and secretory vesicles.

LYSOSOMES

stomach of the cell. low ph very acidic. membrane enclosed besicle that contains powerful digestive enzymes. internal ph reaches 5.0 function includes digestin substancves and recycling organelles.

PERIOXOSOMES

are similar in structure to lysosomes, but are smaller. they contain enzymes that oxidases enzymes that can oxidize (remove hydrogen atoms from..) varous organic substances. for instance, amino acids and fatty acids are oxsidized in this as part of normal

PROTEOSOMES

destroy uneeded, damaged, or faulty proteins. they contain proteases which cut proteins into small peptides. thought to be a foctor in several diseases.

MITOCHONDRIA

POWERHOUSE..bound by double membrane. the outer membrane is smooth, the inner membrane arranged in folds called cristae. this allows for increased surface area for chemical rections of cellular respiration.

SITE OF ATP PRODUCTION BY A CELL:

mitochondria

MITOCHONDRIA

self replicate using thier own dna.

NUCLEUS (director)

most prominent feature of a cell. within the nucleus are the cell's hereditary untis, called genes, which are arranged in single file along chromosomes.

NUCLEAR ENVELOPE

seperates the nucelus from the cytoplasm. both layers of the envelope are lipid bilayers

PARTS OF A NUCLEUS:

nuclear envelope which is perforated by channels called nuclear pores, nucleoli, and genetic material (DNA)

JOB OF NUCELUS:

nuclear pores control the movement of substances between the nucleus and cytoplasm, nucleoli produce robosomes and chromosomes consist of genes that control cellular structure and direct cellular functions.

PROTEIN SYNTHESIS

much of the cellular machinery is devoted to synthesizing large numbers of diverse proteins. the proteins determine the physical and chemical characteristics of cells. the instructions for protein synthesis is found in the dna in the nucleus. protein syth

TRANSCRIPTION

RNA= outside nucleus DNA= inside nucleus. process by which genetic information encoded in DNA is copied onto a strand of RNA called messenger RNA (mRNA), which directs protein synthesis. mRNA takes information outside the cell.

TRANSLATION

reading the mRNA nucleotide sequence to determine the amino acid sequence of the proetien. mRNA has information written in Spanish and need to write to english.

MITOSIS (everything else)

orderly division of the nucleus of a cell that ensures that each new nucleus has the same number and kind of chromosomes as the original nucleus.the process includes the replication of chormosomes and the distribution of the two sets of chromosomes into t

MEIOSIS (gammets)

a type of cell division that occurs during production of gametes, involving two successive nuclear division that result in cells with the haploid (n) number of chromosomes.

CYTOKINESIS

distribution of the cytoplasm into two seperate cells during cell divison, coordinated with nuclear divison (mitosis)

MITOSIS

splits into two cells. ends with cytokinesis

MEIOSIS

splits into four cells and has a stage one and two

CELL DIVISION

1.prophase
2.metaphase
3.anaphase
4.telaphase

PROPHASE

chromatin fibers condense and shorten into chromosomes that are visible under the light mjicroscope.

METAPHASE

microtubles of the mitotic spindle align the centromeres of the chromatid pairs at the exact center of the mitotic spinde.

ANAPHASE

centromeres split, sepataing the two members of each chromatid pair, which move toward opposite poles of the cell

TELOPHASE

final stages of mitosis, telophase, begins after chromosomal movement stops.

WHEN DOES CYTOKYNESIS BEGIN?

late anaphase with the formation of a cleavage furrow, a slight indentation of the plasma membrane, and is completed after telphase.

TELOMERS AND AGING CELLS

specific DNA sequence found only at the tips of each chromosome. these pieces of DNA protect th etips of chromosomes from erosion and from stricking to one another. after many cycles of cell division they can be comepletely gone and even some of the funct

FREE RADICALS AND AGING CELLS

roduce oxidative damage in lipids, proteins or nucleic acids by "stealing" an electron to accompany their unpaired electrons.

CELL IDENTITY MARKER CHANGES IN AGING CELLS:

the immune system may start to attack the body's own cells.as changes in the proteins on the plasma membrane of cells increase, the autoimmune response intensifies, producing the well known signs of aging.