Pharmacology Ch 31 Key Terms

Anion

Negatively charged particle

Bicarbonate

Substance used as a buffer to maintain the normal levels of acidity (pH) in blood and other fluids in the body

Cation

Positively charged electrolyte

Chloride

Major anion (negatively charged ion) found in the fluid outside of cells and in blood

Colloids

Proteins or other large molecules that remain suspended in the blood for a long period of time and are too large to cross membranes

Crystalloids

Intravenous solutions that contain electrolytes in concentrations similar to those of plasma

Dehydration

Condition that results from excessive loss of body water

Edema

Presence of abnormally large amounts of fluid in the intercellular tissue spaces of the body

Electrolytes

Small charged molecules essential for homeostasis that play an important role in body chemistry

Extracellular fluid

Type of fluid that surrounds the cells; consists mainly of plasma found in blood vessels

Homeostasis

Constancy or balance that is maintained by the body despite constant changes

Hypercalcemia

Condition in which the total serum calcium level is higher than 5.16 mEq/liter (2.56 mEq/liter ionized)

Hyperchloremia

Condition in which the serum chloride level is higher than 107 mEq/liter

Hyperkalemia

Condition in which the serum potassium level is higher than 5.5 mEq/liter

Hypermagnesemia

Condition in which the serum level of magnesium is higher than 2.5 mEq/liter

Hypernatremia

Elevation of the serum sodium concentration higher than 145 mEq/liter

Hypertonic

Fluids with a higher osmolarity than serum

Hypocalcemia

Condition in which the total serum calcium level is lower than 4.3 mEq/liter (2.26 mEq/L ionized)

Hypochloremia

Condition in which the serum chloride level is lower than 97 mEq/L

Hypokalemia

Condition in which potassium is lost from the body, resulting in serum potassium level lower than 3.5 mEq/L

Hypomagnesemia

Condition in which the serum level of magnesium is lower than 1.5 mEq/L

Hyponatremia

condition of decreased serum sodium concentration below the normal range (<136 mEq/L)

Hypophosphatemia

Condition in which the serum phosphate level is defined as mild (2 to 2.5 mg/dL, or 0.65 to 0.81 mmol/L), moderate (1 to 2 mg/dL, or 0.32 to 0.65 mmol/L), or severe (<1 mg/dL, or 0.32 mmol/L)

Hypotonic

Refers to fluid with less osmolarity than serum

Intracellular fluid

Fluid inside cells

Ions

Charged particles

Isotonic

Refers to fluid close to the same osmolarity as serum

Magnesium

Fourth most common cation in the body

Milliequivalent (mEq)

Unit used to measure the number of ionic charges or electrovalent bonds (electrolytes) in a solution

Osmolarity

Osmotic pressure of a solution expressed as milliosmoles per liter (mOsm/L) or millimoles per liter (mmol/L) of the solution

Osmosis

The movement of water across a semipermeable membrane from a higher to lower concentration

Potassium

Main electrolyte in extracellular fluid

Sodium

Chief electrolyte in interstitial fluid