Chapter 14 Pierce Genetics

anticodon

Sequence of three nucleotides in transfer RNA that pairs with the corresponding codon in messenger RNA in translation

alternative processing pathways

One of several pathways by which a single pre-mRNA can be processed in different ways to produce alternative types of mRNA

alternative splicing

Process by which a single pre-mRNA can be spliced in more than one way to produce different types of mRNA

branch point

Adenine nucleotide in nuclear pre-mRNA introns that lies from 18 to 40 nucleotides upstream of the 3' splice site

cloverleaf structure

Secondary structure common to all tRNAs

codon

Sequence of three nucleotides that encodes one amino acid in a protein

Colinear

Concept that there is a direct correspondence between the nucleotide sequence of a gene and the continuous sequence of amino acids in a protein

Exons

Coding region of a split gene, after processing the exons remain in messenger RNA

Group II introns

Belongs to a class of introns in some protein-encoding genes that are capable of self-splicing and are found in mitochondria, chloroplasts, and a few eubacteria

Group I introns

Belongs to a class of introns in some ribosomal RNA genes that are capable of self-splicing

Guide RNAs

RNA molecule that serves as a template for an alteration made in mRNA during RNA editing

Introns

Intervening sequence in a split gene; removed from the RNA after transcription

Large ribosomal subunit

The larger of the two subunits of a functional ribosome

lariat

Looplike structure created in the splicing of nuclear pre-mRNA in which the 5' end of an intron is attached to a branch point in pre-mRNA

Modified bases

Rare base found in some RNA molecules. Such bases are modified forms of the standard bases

multiple 3' cleavage sites

Refers to the presence of more than one 3' cleavage site on a single pre-mRNA, which allows cleavage and polyadenylation to take place at different sites, producing mRNAs of different lengths

Nuclear pre-mRNA introns

Belongs to a class of introns in protein-encoding genes that reside in the nuclei of eukaryotic cells

poly (A) tail

String of adenine nucleotides added to the 3' end of a eukaryotic mRNA after transcription

Protein-coding region

The part of mRNA consisting of the nucleotides that specify the amino acid sequence of a protein

RNA editing

Process in which the protein-coding sequence of an mRNA is altered after transcription.

RNA-induced silencing complex

Combination of a small interfering RNA molecule or a microRNA molecule and proteins that can cleave mRNA leading to the degradation of the mRNA

Shine-Dalgarno

Consensus sequence found in the bacterial 5' untranslated region of mRNA

Small ribosomal subunit

The smaller of the two subunits of a functional ribosome

3' splice site

The 3' end of an intron where cleavage takes place in RNA splicing

5' splice site

The 5' end of an intron where cleavage takes place in RNA splicing

spliceosome

Large complex consisting of several RNAs and many proteins that splices protein-encoding pre-mRNA

Transfer RNA introns

Belongs to a class of introns in tRNA genes. the splicing of these genes relies on enzymes

Trans-splicing

The process of splicing together exons from two or more pre-mRNAs

tRNA-modifying enzymes

Creates a modified base in RNA by catalyzing a chemical change in the standard base

5' untranslated region

Sequence of nucleotides at the 5' end of mRNA

3' untranslated region

Sequence of nucleotides at the 3' end of mRNA