osteomyelitis

Osteomyelitis

a severe infection of the bone, bone marrow, and surrounding soft tissue

Staphylococcus aureus

most common infecting organism

Indirect entry of infecting agents is often related to

blunt trauma

Most common sites of indirect entry in children

distal femur, proximal tibia, humerus, and radius

adult comorbidities associated with osteomylitis are

DM, vascular disorders, GU infections & respiratory infections

Direct entry osteomyelitis is often associated with

open wounds (penetrating wounds, fractures)

Sequestra

a fragment of necrosed bone that has become separated from the surrounding tissue

Involucrum

covering of newly formed bone enveloping sequestrum in infection of the bone

Acute osteomyelitis

refers to the initial infection or an infection of less than 1 month in duration

Systemic manifestations of acute osteomyelitis

fever, night sweats, chills, restlessness, nausea, & malaise

Local manifestations of osteomyelitis include

bone pain, swelling, tenderness, warmth and restricted movement

Local bone pain is not relieved by____and worsens with ________

rest; activity

Chronic osteomyelitis refers to bone infection that persists for

longer than one month or an infection that has failed to respond to treatment

Bone or soft tissue biopsy is

the definitive way to determine causitive microorganism

Blood or wound cultures may be

positive for microorganism

WBC may be

elevated

ESR may be

elevated

Normal WBC

4000-11000

Normal ESR

<15-30

Treatment for acute osteomyelitis is

IV antibiotics

Short course of antibiotics may last

4-6 weeks

Longer courses of antibiotics may take as long as

3-6 months

Instruct patients taking gentamicin to notify physician if these symptoms appear:

visual, hearing, or urinary problems

What status should be assessed before starting gentamicin?

hydration

In adults with chronic osteomyelitis, oral therapy of what may be perscribed?

fluoroquinolone

What is another name for flouroquinolone

ciprofloxan (Cipro)

How long is the course of oral Cipro?

6-8 weeks

How is the patients response to medication monitored?

Bone scans and ESR

Surgical treatment for chronic osteomyelitis includes?

removal of tissue and dead bone

Why is tissued removed?

because it is poorly vascularized

What might be implanted to help fight the infection?

antibiotic impregnated polymethl-methacrylate beads chains

What may be used to draw the wound together after surgery?

negative pressure or Wound VAC

When is hyperbaric oxygen therapy used?

refractory cases of chronic osteomyelitis

Is amputation a possibility?

Yes esp. with extensive bone destruction

Complications of long term osteomyelitis include:

septicemia, septic arthritis, pathologic fx, and amyloidosis

Health Hx asessment:

bone trauma, open fx, puncture wounds, strep throat, bac. pneumonia, tooth infection, skin infection, UTI, sinusitis

Three priority nursing Dx:

acute pain, ineffective therapeutic regimen mgmt, impaired physical mobility

At risk patients include:

immunocompromised, orthopedic prosthetics, vascular insufficiencies

Pain control options:

NSAIDs, opioids, muscle relaxants

Types of dressings:

dry, sterile, saline or antibiotics dressings, and wet to dry

Technique when changing dressing

sterile