Magnesium Sulfate
Classification
Miscellaneous Anticonvulsant
Uses
1. Used to manage pregnancy-associated hypertention to prevent seizures in severe preclampsia
2. Used to inhibit preterm labor because of the additional effect in quieting uterine activity (Tocolytic).
Admi
Terbutaline (Brethine)
Classification
Beta adrenergic agent
Action
Stimulate beta-adrenergic receptors of sympathetic CNS. Brochodilation, inhibition of uterine muscle activity, increase pulse rate, increase pulse pressure
Indications
Stop preterm labor. Tolerance and loss of t
Indomethacin (Indocin)
Classification
Prostaglandin synthesis inhibitor
(Drug most often used for tocolysis)
Dosage/Route
Loading dose- 50 mg oral
Maintenance dose- 25 mg PO every 6 hrs for 48 hrs
Use no longer than 48-72 hrs
Contraindications
Limit to use of preterm labor befo
Nifedipine (Procardia)
Classification
Calcium channel blocker (tocotytic)
Dosage/Route
Continued PO therapy- 10-20 mg every 3-6 hrs until muscle contractions are rare. Then administer 30-60 mg every 8-12 hrs until antepartum steroids have been administered.
Contraindications
Pa
Misoprostol (Cytotec)
Classification
Antiprogesterone
Used in conjuction with Mifepristone as means for fetal abortion up to 9 weeks of gestation. Also used to treat post partum hemmorage
Administration-
Initial dose is 600 mg PO of Mifepristone followed by 400 mcg (PO or vagi
Carboprost Tromethamine (Hemabate, Prostin/15m)
Classification
Prostaglandin, Oxytocin
Used in abortion. Also used to treat post partum hemmorage
Administration-
Postpartum hemorage- 250 mcg IM. May repeat at 15-90 min intervals. Not to exceed 2 mg.
Contraindications
Women with hypersensitivity to pros
Betamethasone (Dexamethasone)
Classification
Corticosteroid
Acceleration of fetal lung maturity to reduce the incidence and severity of Respiratory Distress Syndrome
Dosage/Route
12 mg IM for two doses 24 hrs apart
Contraindications
Active infection (such as chorioamnionitis)
Precauti