Maternity & fetal development, Leifer #1

Ova

always contributes an X chromosome

Ovum

can survive up to 24 hrs after ovulation

Sperm

carries X or Y chromosome and can survive in the cervix for up to 5 days after ejaculation

Zygote

cell formed by the union of the sperm and the ovum, which is transported to the uterus through the fallopian tube;
IMPLANTS IN THE UPPER SECTION OF THE POSTERIOR UTERINE WALL

Fertilization of the zygote

usually occurs in the outer third of the fallopian tube

Blastomere

has 8 cells

Morula

solid ball of cells that begins on day 3 and lasts 2-4 days in the uterus

Blastocyst

inner layer of cells which develops into the embryo and embryonic membrane (chorion)
OCCURS ON THE 9TH DAY AFTER FERTILIZATION AND INITIATES THE PRODUCTION OF RED BLOOD CELLS UNTIL WEEK 6

Chorion

embryonic membrane; outer layer of embryonic cells that develops from the trophoblast (envelops the amnion, embryo, and yolk sac) has villi

Endometrium

prepared lining of the uterine wall in which the zygote burrows

Decidua

Endometrium becomes this after implantation

Decidua Basalis

area UNDER the blastocyst that gives rise to the maternal part of the placenta

Amnion

inner layer of the sac that protects the embryo and forms the boundaries of the amniotic cavity

Amniotic sac

Chorion and Amnion together form this filled with water

Amniotic fluid

clear with mild odor and bits of vernix; VOLUME AT 37 WEEKS = 1000 mL

Fetus may swallow up to

400 mL of amniotic fluid per day

Functions of the Amniotic Fluid are

Maintain even temperature
prevent sac from adhering to fetal skin
Allow symmetrical growth
Allows buoyancy and fetal movement
Acts as a cushion

Germ layers of zygote in blastocyst stage are

ectoderm, mesoderm and endoderm

Week 3 of embryo

single tubular
heart begins pumping
and neural tube forms; Mesoderm and primitive spinal cord and brain appear

Week 8 of embryo

distinct human appearance and purposeful movement occurs and SEX ORGANS form (genitalia is visible on ultrasound at week 10)

Week 17-20

Genitalia are visible on ultrasound and mother can feel movement

Week 20

fetus lungs are functionally mature and AGE OF VIABILITY

Gestational age of 25 weeks

we should try to heroically save and treat baby if born

Week 28 of Fetus

eyes open

Full term fetus

Weeks 38-40

Placenta

temporary organ for fetal respiration (oxygen), nutrition, and excretion - ALSO FUNCTIONS AS AN ENDOCRINE GLAND

TWO umbilical arteries

fetal deoxygenated blood and waste products leave the fetus and enter the placenta

ONE Umbilical Vein

Takes IN OXYGEN and nutrients returning to the fetus

Fetal hormones produced by the placenta

progesterone, estrogen, hCG and hPL

Progesterone

Maintains uterine lining
reduces uterine contractions (to prevent abortion)
prepares the glands of the breast for lactation
stimulates testes to produce testosterone

Estrogen

stimulates uterine growth
increases blood flow to the uterine vessels
stimulates breast DUCTS
skin pigments
stuffy nose
increased salivation

hCG

sends the signal to the corpus luteum that conception has occurred detectable in maternal blood as soon as 7-9 days after fertilization

Wharton's jelly

covers the cord vessels

hPL

causes decreased insulin sensitivity and utilization of glucose by the mother

Circulation of the blood through the placenta

is well established after the 4th week

Ductus Venous

diverts blood AWAY from the liver and returns it from the placenta

Foramen Ovale

diverts blood from the right atrium to the left atrium (opening between the atriums); this closes functionally w/in 2 hours after birth
Closes permanently by age 3 months

Ductus Arteriosus

diverts blood from the pulmonary Artery into the Aorta

Early Decelerations (in labor)

are the fetus's response to altered fetal cerebral blood flow and fetal head compression

Variable Decelerations (in labor)

are associated with umbilical cord compression

Late decelerations (in labor)

are associated with uteroplacental insufficiency

Latent first phase of labor

from the beginning of true labor until
4 cm
of cervical dilation

Active phase of labor

characterized by cervical dilation of
4 to 7 cm

Transition phase of labor

dilation from
7-10 cm

Second stage of labor

cervix is completely dilated until the birth of the baby

Third stage of labor

Expulsion of the placenta

Lochia Rubra

consists of blood and decidual debris and lasts for 3 days after birth

Lochia Serosa

pinkish tinged blood and mucus that lasts from days 3- 10 after birth

Lochia Alba

white mucus that lasts from days 10-21 after birth; should have no odor