Pharmacology Prefixes & Suffixes

cef- or ceph-

antibiotic; 5% cross sensitivity with penicillin, can cause GI upset

-cillin

antibiotic; common allergy, GI distress

-mycin

macrolide antibiotic; renal toxicity, ototoxicity with aminoglycosides

-cycline

anti-infectives; dental problems for fetus if taken in pregnancy or before age 8, interferes with oral contraceptives

-gliptin

treating diabetes; watch for respiratory infections, headaches

-oxacin

antibiotic; photosensitivity reaction

-azoles

antifungal; liver toxic, many drug-drug interactions

-mab

monocloncal antibody; injected, flu-like symptoms

-pine

calcium channel blocker; monitor BP and rhythm

-pril

ACE inhibitor; monitor cough

-sartan

angiotensin receptor blocker; not to be used during pregnancy

-olol

beta blocker; monitor cardiovascular effects, caution with diabetes

-ol

beta agonist; rapid heart rate, sympathetic reaction

-osin

alpha blocker; first dose reaction, monitor for congestive heart failure

-parin

anticlotting agent; injected, monitor for excessive bruising or bleeding

-thiazide

diuretic; weight loss, fluid and electrolyte balance

-ase

enzyme, usually used with thrombolytics; monitor for bleeding

-statin

HMG CoA inhibitor; pregnancy category X, with diet and exercise, rhabdomyloysis

-triptan

antimigrain drug; monitor bp and cardiac effects

-enafil

impotence drug; not with nitrates or alpha blockers, must be used with sexual stimulation

-barbital

barbiturate; CNS depressant, stimulates liver enzymes to metabolize drugs

-pam

benzodiazepine; liver and renal toxicity

-lukast

leukotrience receptor antagonist; asthma maintenance drug, not used in acute asthma attack

-stim

colony stimulating agent; injected, check bone marrow

-prazole

antisecretory agent; PPI are not for prolonged use, can cause hip fractures

-setron

centrally acting antiemetic; injected, CNS depression

-azine

phenothiazine; CNS depression

-sone

corticosteroid; timing of dose, risk of infection

-esterone

progestin; annual pap smear

-dronate

calcium regulator; dosing details, monitor calcium

-olone

anabolic steroid; liver and heart toxicity

-asteride

androgen inhibitor; monitor urinary output

-profen

NSAID; monitor GI bleed