METABOLIC STRESS

ebb phase

flight response
unchanged metabolism
body temp deceased
o2 consumption decreased
glucose-increased
lactate-increased
furl-glucose/fat

flow

fight response
hypercatabolic
hypermetabolic
increased temp
increased o2 comsumption
glucose-increased
lactate-increased
fuel source-fat/glucose/ amino acids/ lean muscle

adrenal insuffiency
primary
secondary

- Primary: inability of the gland to secrete cortisol or aldosterone
- Secondary: inability of the HPA to release ACTH

adrenal insufficiency s/s

fever
tachycardia
orthostatic hypotension
hypotension- not responsive to vaso
aneroxic
hyperkalemia
hypo na
hypoglycemia
acidosis
increased BUN
weak

adrenal insuff. dx

rapid acth
going to see how adrenal respond to acth
supposed to increase cortisol levels
- Do ABGs before and Allen Test
- Plasma ACTH levels from aterial
- ACTH (250mcg) given IV or IM
- Second plasma level drawn 60-90mins later
- Low = secondary adrenal

adrenal insuff TX.

hydrocortisone
weight bearing exercises
JUST DONT STOP MED
increased risk for infections

hyperthyroid/hypo thyoid not covered too easy

...

Non thyoid illness syndrome

decreased t3
normal t4/tsh
not responsive to thyroid hormone

hyperglycemia tx
DKA /HHS

� Restore fluid and electrolyte balance
� IV insulin
� Maintain glucose level of 140-180mg/dL
� Identify causative factors