Which drug is an Antiemetic and Antivertigo
Meclizine
Which drug is indicated for vertigo?
Meclizine
Which drug has the following side effects?
?Xerostomia (dry mouth)
?Sedation
?Somnolence
Meclizine
Which drug has the following serious effects?
?Blurred Vision
?Anaphylaxis
Meclizine
Which drug has OTC= Bonine or Dramamine *
Meclizine
Which drug is
?Antiemetic
?Dopamine Antagonist
Metoclopramide
Which drug is indicated for Diabetic gastroparesis *
Metoclopramide
Which drug has an adverse effect of Asthenia *
Metoclopramide
Which drug has serious effects including
?Neuroleptic malignant syndrome
? Tardive dyskinesia *
Metoclopramide
Which drug should you
�Advise patient to avoid concomitant MAO inhibitors, tricyclic antidepressants, or sympathomimetic amine therapy
Metoclopramide
Which drug?
�Oral formulations should be taken 30 min before meals and at bedtime, or as a single dose prior to the provoking situation.
Metoclopramide
Which drug is in this class?
?Antiemetic
?Serotonin Receptor Antagonist, 5-HT3
Ondansetron
Which drug is indicated for the following:
?Prophylaxis for Chemotherapy-induced nausea and vomiting for highly emetogenic and moderately emetogenic chemotherapy
?Prophylaxis for Postoperative nausea and vomiting
?Prophylaxis for Radiation-induced nausea
Ondansetron
Which drug has this adverse effect?
Malaise
Ondansetron
Which drug has this as a serious effect?
?Torsades de pointes *
Ondansetron
Which drug has this teaching?
�This drug may cause constipation, diarrhea, headache, fatigue, or malaise
Ondansetron
Which drug
�Drug Class
?Antigout
?Xanthine Oxidase Inhibitor
Allopurinol
Which drug
Indications
?Gout
?Hyperuricemia - Tumor lysis syndrome (because works on uric acid)
?Calcium renal calculus, recurrent
?Cancer - Hyperuricemia
Allopurinol
Which drug has this common effect
?Pruritis (itching)
?Maculopapular Eruptions *
Allopurinol
Which drug has this serious effect
?Stevens-Johnson syndrome *
Allopurinol
Which drug has this teaching?
�Report signs/symptoms of hepatotoxicity (anorexia, weight loss, or pruritus) immediately to MD
Allopurinol
Which drug has this teaching?
�Optimal benefit may be delayed for 2 to 6 weeks
Allopurinol
Which drug has this teaching?
�Take drug after meals to reduce gastric irritation
Allopurinol
Which drug has this teaching?
�Maintain adequate hydration during therapy to prevent renal stones
Allopurinol
Which drug
�Drug Class
?Antigout
Colchicine
Which drug has these indications
?Gout - Treatment and Prophylaxis
?Familial Mediterranean fever *
Colchicine
Which drug has this effect?
?Diarrhea **
Colchicine
Which drug has this serious effect?
Myelosuppression
Colchicine
Which drug has this teaching?
�Advise patient to discontinue drug and immediately report signs/symptoms of neuromuscular toxicity including rhabdomyolysis]
Colchicine
Which drug has this teaching?
�Instruct patient to not eat grapefruit or drink grapefruit juice with drug (inhibitor of CYP 3A4)
Colchicine
Which drug has this teaching?
�Advise patient that there are multiple significant drug-drug interactions for this drug. Consult healthcare professional prior to new drug use (including OTC and herbal drugs)
Interacting drugs are P-glycoprotein inhibitors
Colchicine
Which drug has this �Drug Class
?Prostaglandin analog
Latanoprost
Which drug is indicated for glaucoma
Latanoprost
Which drug has this effect
?may increase the brown pigmentation in the iris, changing eye color to brown*
? may cause eyelashes to grow longer, thicker, and darker in color*
Latanoprost
Which drug has this serious effect?
?Shortness of breath
?Wheezing
?Chest tightness
Latanoprost
Guanosine Nucleoside Analog
Viral DNA Polymerase Inhibitor
Top Drug in this class:
Valacylovir (Valtrex�)
Which drug is indicated for the following?
?Herpes zoster, Shingles *
Varicella
Valacylovir
Which drug?
�Adverse Effects (Common):
?Rash
?Abdominal pain
?Nausea
?Headache
?Fatigue
Valacylovir
Which drug has these serious effects?
?Thrombotic thrombocytopenic purpura *
nBlood clots in small blood vessels; leads to low platelet counts
?Hemolytic uremic syndrome *
nRed blood cell destruction causes kidney injury
Valacylovir
Which drug has this teaching?
�Instruct patient to avoid having sex while herpes sores are present. This drug does not prevent disease transmission.
Valacylovir
Which drug has this teaching?
Patient should maintain adequate hydration during drug therapy to prevent precipitation of acyclovir (active drug) in the renal tubules.
Valacylovir
Which drugs are Nonbarbiturate Hypnotics
�Zolpidem (Ambien�)
�Eszopiclone (Lunesta�)
Which drug is indicated for the following?
Insomnia, Characterized by difficulty returning to sleep after middle-of-the-night awakening
Zolpidem
Which drugs are indicated for insomnia
Zolpidem
Eszopiclone
Which drugs have the following adverse effects?
drugged state
Zolpidem
Eszopiclone
Which drug has an unpleasant taste
Eszopiclone
Which drugs have these adverse effects
�Adverse Effects (serious):
?Depression worsening
?Suicidal thoughts
Zolpidem
Eszopiclone
Which drugs are �Schedule IV - remember refill allowances *
Zolpidem
Eszopiclone
Which drugs have this clinical teaching
�Patient should NOT take this medicine with or immediately after a heavy/high fat meal
Zolpidem
Eszopiclone
Which drugs have this teaching
�Take immediately before bedtime or when the patient has gone to bed and experienced difficulty falling asleep
Zolpidem
Eszopiclone
Which drug has this class: �Monoamine Oxidase Type B Inhibitor
Selegiline (Eldepryl�, Emsam�-transdermal, Zelapar� ODT)
Which drug has these indications
�Indications
?Management of Parkinson's Disease
?Depression (transdermal)
Selegiline
Common side effects for what drug
�Headache
�Insomnia
�Nausea
�Application site reaction (transdermal)
Selegiline
Which drug has these serious effects
�Hallucinations
�Dyskinesia
�Black Box Warning- Transdermal- increased risk of suicide in children, adolescents, and young adults
Selegiline
Which drug has this clinical teaching
�ODT- Take in the morning before breakfast, place on top of the tongue and allow to dissolve; avoid food or liquid for 5 minutes before or after administration
Selegiline
Which drug has this clinical teaching?
�Transdermal- Apply to clean, dry, intact skin to the upper torso (below the neck and above the waist)
Selegiline
Which drug has this clinical teaching
�Many drug interactions; avoid concomitant use with dextromethorphan, methadone, tramadol, or other MAO inhibitors
Selegiline
Which drugs are in the following drug class?
?Antimuscarinic
?Urinary Antispasmodic
Oxybutynin (Ditropan�)
Tolterodine ER (Detrol LA�)
Which drugs are indicated for
Bladder muscle dysfunction
Oxybutynin (Ditropan�)
Tolterodine ER (Detrol LA�)
Common side effects that both Oxybutynin and
Tolterodine ER have
Xerostomia - dry mouth
constipation
Which drug has this common side effect
�Local irritation when applied as patch/gel*
Oxybutynin
Which drugs have these serious effects
�Adverse Effects (Serious)
?Anaphylaxis
?Angioedema
Oxybutynin (Ditropan�)
Tolterodine ER (Detrol LA�)
Which drug is in this drug class
�5-Alpha Reductase Inhibitor
?Finasteride
which drug is in this drug class
�Alpha-1 Adrenergic Blocker
?Tamsulosin (Flomax�)
?Terazosin (Hytrin�)
Which drug is indicated for BPH and Male pattern alopecia
Finasteride
Which drug
�Adverse Effects (Common):
?Abnormal ejaculation
?Breast tenderness
?Reduced libido
Finasteride
Which drug
�Adverse Effects (Serious):
?Neoplasm of male breast
?Prostate cancer
Finasteride
Which drug has the following teaching
�Pregnancy Category X: Warn pregnant women to avoid handling crushed or broken tablets due to potential risks to a male fetus.
Finasteride
Which drug has this teaching
instruct �patient to immediately report breast changes such as lumps, nipple discharge, pain, enlargement, or tenderness
Finasteride
Which drug has this teaching
�Advise patient using drug for hair loss that symptomatic improvement may not occur for 3 months or longer
Finasteride
Which drug is indicated for BPH
Tamsulosin
which drug is indicated for BPH and hypertension
Terazosin
Which drug has these effects
orthostatic hypotension
headache
Tamsulosin and Terazosin
Which drugs have these serious effects
?Retinal detachment
?Priapism *
?Syncope *
Tamsulosin and Terazosin
Which drug has this teaching
�Tell patient to rise slowly from a sitting/lying position, as this drug may cause orthostatic hypotension ****
Tamsulosin and Terazosin
Which drug has this teaching
�Advise patient against sudden discontinuation of drug, as this may cause rebound hypertension
Tamsulosin and Terazosin
Which drug is in this class
Phosphodiesterase Type 5 Inhibitors
(PDE5 inhibitors)
Tadalafil
Which drug has this indication
�Indications
?BPH
?Erectile dysfunction
Tadalafil
Which drugs have this indication
?Pulmonary hypertension
Sildenafil (Revatio�)
Tadalafil (Adcirca�)
Which drug has this common effect
?Visual disturbance *
Tadalafil
Which drug has this serious effect
�Decreased hearing *
Tadalafil
Which drug has this teaching?
�May cause angina, dizziness, and nausea in patients with preexisting cardiovascular risk factors
Tadalafil
Which drug has this teaching
�Report an erection that persists longer than 4 hours
Tadalafil
Which drug has this teaching
�Report sudden decrease or loss of hearing or vision. Hearing loss may be accompanied by dizziness and tinnitus.
Tadalafil
Which drug has this teaching
�For erectile dysfunction, patient should take drug prior to sexual activity, but not more than once per day
Tadalafil
Which drug has this teaching
�Instruct patient taking these medications for pulmonary hypertension not to take any other phosphodiesterase type 5 inhibitors for any other indication
Tadalafil
Which drug has this teaching
�Patient should not take this medicine if using alpha-blockers or nitrates, as life-threatening hypotension may occur
Tadalafil
Which drugs are Cholinesterase Inhibitors
Donepezil (Aricept�)
Rivastigmine (Exelon�)
Which drug is an N-Methyl D-Aspartate Receptor Antagonist
Top Drug: Memantine (Namenda�)
Which drug has this indication
Alzheimer's disease (mod-severe)
DONEPEZIL
Which drug has this indication
Parkinson's disease dementia (mild/mod)
RIVASTIGMINE
Which drugs
�Adverse Effects (Common):
?Weight loss
?GI upset
?Dizziness
Donepezil (Aricept�)
Rivastigmine (Exelon�)
Which drugs
�Adverse Effects (Serious):
?Bradyarrhythmia*
?Torsades de pointes
?GI hemorrhage
Donepezil (Aricept�)
Rivastigmine (Exelon�)
Which drugs are
�Recommended to take with food, but not required
Donepezil (Aricept�)
Rivastigmine (Exelon�)
Which drugs have this teaching
�Dosage adjustment required if dose missed for several days
Donepezil (Aricept�)
Rivastigmine (Exelon�)
- available in a patch form
Rivastigmine
which drug has the following indication
?Alzheimer's Disease (mod - severe)
Memantine
Which drug
Adverse Effects (common):
?Hypertension
?Hypotension
?Syncope
?Confusion
?Dizziness
?Headache
Memantine
Which drug
Adverse Effects (serious):
?Stevens-Johnson syndrome
?Deep venous thrombosis
?Hepatitis, Liver failure
?Cerebrovascular accident (CVA)
?Transient ischemic attack (TIA )
?Seizure
?Acute renal failure
?Neuroleptic malignant syndrome
Memantine
Which drug has this teaching
�Instruct patient and/or caregiver on appropriate dose frequency (twice daily if greater than 5 mg/day) and dose escalation (no less than 1 week between dose increase)
Memantine
Which drug has this teaching
�If patient is unable to swallow the extended-release capsule, open the capsule and sprinkle the contents on applesauce. The entire mixture should be consumed as a single dose
Memantine
Which drug is a muscle relaxant
Cyclobenzaprine (Flexeril�)
Which drug is indicated for
?Skeletal muscle spasm
Cyclobenzaprine
Which drug has these effects
�Xerostomia * - excessive dry mouth
�Dizziness *
�Somnolence *
Cyclobenzaprine
Which drug has these effects
Adverse Effects (serious):
�Hepatitis
�Jaundice
Cyclobenzaprine
Which drug has this teaching
�Instruct patient to report use of a MAO inhibitor within the last 14 days prior to initiating drug therapy.
Cyclobenzaprine
Which drug has this teaching
�Instruct patients to report signs/symptoms of decreased hepatic function, especially in patients with pre-existing hepatic disease
Cyclobenzaprine
Which drug has this teaching
�Drug is not intended for long-term therapy. Advise patient to report if signs/symptoms do not improve within 2 to 3 weeks of therapy **
Cyclobenzaprine
Which drug has this teaching
�Avoid concomitant use of tricyclic antidepressants with this drug.
Cyclobenzaprine