PTA Pathology Final Study Set

Morbidity

Indicates the disease rates within a group

Atrophy

Decrease in size of cell, thus reduced tissue mass. Reduced use of tissue, insufficient nutrition

Hypertrophy

Increase in size of cells. Enlarged mass. Additional work of tissue, excessive hormonal stimulation

Hyperplasia

Increase in # of Cells. Enlarged tissue mass

Metaplasia

Certain Cell type being replaced by another cell type EX: Strat Squamous (Chronic Inflammation) Get replaced by columnar cells...

Dysplasia

Completely Changes (Not a consistant change) varies in shape, size-design of cell no longer has its purpose Ex: Diabetic Ulcer: Getting inflammed tissues forming can be dysplastic in nature

Anaplasia

Undifferentiated Cells (Structures) Cancer type cell, Uncontrolled EX: Aggressive Tumors

Neoplasm

Any tumor Beigin or Malegent Ex: Beigin has potential to turn into Malegnent

Ischemia

Deficient in Oxygen.

Necrosis

A group of cells that die

Name Two common causes of Cell Damage

Chemical Toxins & Microorganisms

Ischemia vs Infarction

Ischemia: Temporary loss of oxygen Infarction: Loss of Oxygen regarding cell death

Erythemia

Redness, often associated with warmth around the area. Often indicates increased blood flow

Transudation

Passage of fluid through a membrane/tissue.

Which of the following would not be included as one of the bodys three basic lines of defense:
A. Mucus Membranes
B. Immune System
C. Fibronectogenesis
D. Skin
E. Phagocytosis

C. Fibronectogenesis -This word is made up

Cardinal Signs of Inflammation

Erythema or Rubor: Redness
Calor: Heat
Dolor: Pain
Tumor: Swelling
Functio Laesa: Loss of function

Treatment of Inflammation

R: REST
I: ICE
C: COMPRESSION
E: ELEVATION

Healing process

Inflammation (0-5) days
Repair (Proliferation) (3-21) days
Remodeling (Maturation) (3wks-24mnths)

Proteoglycans

Bind to fibronectin and to collagen to stabilize the tissue during repair

Hemostasis

Blood filling the wound, allowing it to "clog" through the use of platelets

Degeneration

Formation of a hematoma, necrosis for dead cells to start the inflammatory response

Pain fibers are ____ fibers

Afferent fibers

Nociceptors

Are sensory receptors, stimulated by thermal, chemical, and physical

Reflex response

The reflex response is the involuntary muscle contraction AWAY from pain

According to the gate-control theory, passage of pain impulses may be naturally blocked:
A: at the synapse by entry of other sensory impulses
B: by the stress response
C: by administration of morphine directly into the spinal cord
D: by referring the pain

A: At the synapse by entry of other sensory impulses

Somatic Pain

From skin, bone muscle, conducted by sensory fibers

Visceral Pain

Originates in organs, conducted by symapthetic fibers

Radicular Pain

Nerve root, can be felt via the motor root (myotome), or dermatome (sensory)

T/F : Acute pain is typically associated with a dull/aching sensation. It typically indicates fatigue & is associated with changes in weight

FALSE; its chronic

How does the body recognize self from non self?

Antigens

These cells "TAG" foreign material for consumption

Macrophages

Anaphylaxis

Severe life threatening systemic hypersensitvity reaction, resulting in decreased blood pressure, airway obstruction and severe hypoxia

Metastasis

Spread of a disease from one organ to another

Sarcoma

Malignant Connective tissue

Carinoma

Malignant Epithelial tissue

Anemia

Anorexia, decreased food intake, chronic bleeding, bone marrow depression

Mental retardation, flattened facial characteristics, under developed intestines, congenital heart defects, aa subluxation, decreased tone and ligament laxity

Down Syndrome

Mental retardation, may be addressing functional deficits and management of

Fragile X syndrome

Various degrees of motor deficits, developmental delay

Cerebral Palsy

UE traction injury (waiters tip position)

Erbs Palsy

Cardiac Output determined by

Stroke Volume x Heart rate.. Normal cardiac output s 5L/min

Rating of perceived exhertion

6-20

Ventricular fibrilation

serious & leads to complete loss of muscle contractions in the heart

Oliguria

No urine output

This abnormal growth of cells has metasizes from one cell to another

Secondary Tumor

This disease is involved in reduction hemogolbin synthesis. Symptoms can be mild to severe

Iron Def. Anemia

T/F: Patient has hemoglobin 10g/100ml is this considered anemia

True

Lack of Vitamin b12 causes

Polycythemia

This bleeding disorder can cause excessive bleeding but has a good prognosis

Hemophelia

T/F: One characteristic in hodkins and non hodkins is that hodkins only involve a single lymph node

True

Patient taking a vasoilator

Reduces peripheral resistance

Pt. in outpatient setting experiencing crushing chest pain

Angina pectoris/exertional angina

T/F: Cardiac disrhythmia are deviations that are not normal sounds in heart

TRUE

This respiratory tract infection is best known as the common cold

Infectious Rhinitis

This respiratory Tract infection is identified because it is typically bacterial based, and causes headache and pain with patients

Sinusitis

This respiratory tract infection is viral, is sudden onset and can result in hospitalization for pneumonia. The pneumonia is the cause of deaths

Influenza (flue

This respiratory tract infection is often diffuse, affecting both lungs. The greatest concern it causes inflammation in the alveoli

Bronchopneumonia

This respiratory pathology involves a genetic disorder. It is characterized by tenacious mucous from the exocrine glands. A sweat test is the best diagnosis to test for it

Cystic Fibrosis

T/F: Shortness of Breath=Subjective, Dyspnea is Objective

TRUE

T/F: your patient is coughing up sputum and while as TB, is not considered active. You do not need to use gown/glove in the inpatient setting

TRUE

A pink puffer is consistent with which respiratory disease

Predominant Emphysema

A blue bloater is consistant with which respiratory disease

Bronchitis

Impairment or failure of bone marrow, may be temporary or permanent

Aplastic Anemia

Results from excessive destruction of RBCs

Hemolytic Anemia

This is a symptom of an underlying pathology, that caused by difficulty absorbing vitamin b12. It leads to decreased efficiency of red blood cells

Pernicious Anemia

Most common inherited clotting disorder, spontaneous bleeding in joints

Hemophilia A

Atrial contraction

P wave

Ventricle Contraction

QRS

Repolarization of Ventricle

T wave

(Heart attack) Occurs when coronary artery is totally obstructed, Atherosclerosis (Clogging of the pipes) is most common cause

Myocardial Infarction

Heart cannot maintain pumping capability, cardiac output or stroke volume decreases

Congestive Heart Failure (CHF)

Disease in arteries outside the heart, brain not getting enough blood flow

Peripheral Vascular disease: Atherosclerosis

Loss of circulating blood volume

Hypovolemic Shock

Inability of heart to maintain cardiac output to circulation

Cardiogenic Shock

Alternate means for most tissue to get blood supply. Can reduce the risks of blockage of heart vessels by giving alternate blood supply to areas of heart muscle

Collateral Circulation

Common viral infection particularly in children, self limiting (some cold symptoms)

Laryngotrracheobronchitis (Coup)

Most prevalent type of influenza viruses

Type A

Sputum: Yellowish, green cloudy, thick mucus

Bacterial Infection

Sputum: Rusty or dark colored

Pneumonia

Sputum: Large amount of purulent sputum with foul odor

Bronchietasis

Sputum: Thick Tenacious Mucus

Asthma or Cystic Fibrosis

Inherited genetic disorder, gene located on chromosome seven, tenacious mucus from exocrine glands

Cystic Fibrosis

To Choke on something: Passage of food, fluid, emesis, other foreign material into trachea and lungs

Aspiration

Dypsnea that occurs while lying down

Orrthopnea

Inadequate oxygen in blood

Hypoxemia

Increased carbon dioxide in blood. Increases CO2 = decreased PH which makes the PH more acidic

Hypercapnea

Respiratory Tract infection where you would take airborne precautions and wear N95 mask

TB

Collapse of a lung or part of lung, leads to decreased gas exchange & hypoxia

Atelectasis

Air in pleural cavity, No normal opening in chest wall. "These are all closed, that is there is no opening to the outside.

Pneumothorax

Atmospheric air enters the pleural cavity through opening in chest wall "sucking sound

Pneumothorax II

Fracture of Ribs, Ribs move independently during respiration

Flail Chest

Bone broken forming separate peices

Complete Fracture

Bone only partially Broken

Incomplete Fracture

Skin is broken

Open (Compound) Fracture

Skin is not broken

Closed Fracture

Single break, maintain alignment & position

Simple Fracture

Multiple fractures and bone fragments

Comminuted fracture

Bone crushed or collapsed into small peices

Compression Fracture

One end forced into adjacent bone

Impacted fracture

Results from weakness, occurs with little stress

Pathologic fracture

Fatigue or repetitive fractures

Stress fractures

Skull fractured and forced into brain

Depressed fracture

Involves ligaments in musculoskeletal injuries

Sprains

Involves muscle in musculoskeletal injuries

Strains

In healing of bone fracture, what forms new cartilage

Chrondoblasts

In healing of bone fracture, what generates new bone

Osteoblasts

In healing of bone fracture, what removes the debris

Phagocytic cells

In healing of bone fracture, what lays down new collagen fibers

Fibroblasts

Most common type of MD, affects young boys

Pseudohypertrophic MD

Pushing on hips to go into standing position

Muscular Dystrophy: Gower maneuver

Degeneratve Joint Disease

Osteoarthritis: Wear and tear joint disease

Crepitus, Trendelenburg gait, genu valgus, nodes on hands, hallux valgus (bunion) on feet

Osteoarthritis characteristics

Affected Joints extremely painful, stiffness of joints, redness, swelling, joint movement impaired

Rhematoid Arthritis

A chronic progressive inflammatory condition, more common in men 20-40 years: Vertebral joints inflammed, fusion of joint, kyphosis develops

Ankylosising Spondyltis

Female prevalent, malar rash, global arthritic like symptoms

Systemic Lupus

If the (L) cerebral hemiphere is involved what is affected

aphasia

Brochas Area affects

speech

Warnikes area affects

Language comprehension

Occipital Lobe affects

Vision

Cerebellum affects

Coordination

Dysarthria

disturbance in articulation of speech

agraphia

inability to write

Ideomotor apraxia

inability to voluntary perform learned tasks

Addisons disease

All of the above

Which of the following are signs and symptoms of hypoglycemic shock

A, C &D

The function of the liver includes all except?

Production of digestive enzymes

The most common type of hepatitis transmitted by blood transfusion is

Type C

Celiac disease is digestive disorder that can not break down

Gluten

What is not a cause of Dysphagia

Decreased saliva production

What would be considered a medical emergency

Blockage of small intestine

People often mistake this type of skin disorder. It can appear on the epidermis but most important if identified correctly, prognosis is excellent if removed in reasonable time.

Squamous Cell Carcinoma

This variant of jaundice your patient will become excessively fatigued, due to anemia. The reason is their jaundice caused destruction of red blood cells. Which variant of Jaundice is this?

Prehepatic Jaundice

This neurological disorder involves an inherited disorder that is a progressive atrophy of the brain

Huntingtons disease

You perform a chart review and the WBC indicated a count of 12,000 mm3. This makes you consider that

Your patient is having an autoimmune infection

The impaired absorption of cerebrospinal fluid is tolerated for some time for neonates because their skull can expand. It can create brain damage in adults. What is this pathology

Non-Obtrusive Hydrocephalus

The small intestine contains this structure that assist in the absorption of material

Microvilli

This is a complimentary therapy health care specialist. Their focus is activities of daily living with emphasis on upper lower extremity dressing

Occupational Therapy

Identify the correct information regarding the pancreas

Insulin converts blood glucose to glycogen. Glycogen is stored in the liver and muscle.

Injury of brain tissue and rupture of blood vessels, but the skull fracture NOT occurring is what type of head injury

closed head injury

This route of drug administration has a rapid onset, but requires a specific " technique". ideal for respiratory pathologies

Inhalation