Clin Med 3: Things I highlighted in my study guide :)

Systolic murmurs

#NAME?

Diastolic murmurs

#NAME?

Malar facial flush

Symptom in mitral stenosis

Austin Flint Murmur

Middle to late diastolic rumble caused by vibration of anterior mitral valve leaflet when struck by regurgitant jet in Aortic Regurgitation

Treatment of Tricuspid Stenosis

Bioprosthesis

Carcinoid Heart Disease

primary carcinoid tumors with metastatic spread to liver
- neuroendocrine malignancy
- secretion of vasoactive substance (serotonin, histamine)
- Occurs in pulmonic stenosis

Treatment of Pulmonic Stenosis

Balloon valvuloplasty (carcinoid cause has poor response to valvuloplasty)

Treatment of Tricuspid Regurgitation

Annuloplasty

Graham Steell Murmur

high pitched, blowing decrescendo diastolic murmur immediately after P2 with pulmonary systolic arterial pressure > 70mmHg in pulmonary regurgitation

Symptoms of Aortic Stenosis

Exertional chest pain
Syncope
Shortness of breath
CHF
Angina

Diagnosis of Aortic Stenosis

Cath = GOLD STANDARD

Predominant Cause of Mitral Stenosis

Rheumatic Heart Disease

Treatment of Mitral Regurgitation

ACEi = Hallmark (afterload reduction to reduce regurgitation)

4 Distinct Features of Tetrology of Fallot

1. Right ventricular outflow tract obstruction
2. Ventricular septal defect (nonrestrictive)
3. Aortic override of the ventricular septum
4. Right ventricular hypertrophy

Patent Ductus Arteriosus

- CHF most common cause of death
- HARSH, CONTINUOUS MURMUR (machinery-like), envelops second heart sound

Chest X-ray Coarctation of Aorta

Rib notching
FIGURE OF 3 SIGN
enlarged intercostal collaterals

Eisenmenger Physiology

Left ventricle has higher pressure than the right ventricle, so it shunts left to right; eventually reverses
- Seen with Ventricular Septal Defect

Patent Foramen Ovale

Clinical importance = HIGH risk of stroke
- Bubble study to test

Percentage of Aneurysms that involve the abdominal aorta

75%

Still's Murmur

- "Innocent" murmur
- Systolic murmur
- Vibratory/musical quality
- Differential = small ventricular septal defect, subaortic stenosis

Jones Criteria

- Evaluate for Rheumatic Fever
- previous upper airway infection with GAS detected with either 2 major manifestations or 1 major and 2 minor
- Major = carditis, polyarthritis, chorea, erythema marginatum, subcutaneous nodules
- Minor = fever, arthralgia, elevated erythrocyte sedimentation rate, elevated C reactive protein, prolonged PR interval

Hallmark of Rheumatic Carditis

Mitral insufficiency

Most Common Manifestation of Rheumatic Fever

Arthritis

Sydenham's Chorea

purposeless and involuntary movements of face and limbs, muscular hypotonia, emotional liability
- Diagnostic of Rheumatic Fever

Drug of Choice for Rheumatic Fever

Penicillin

5 H's of Hypotension

Hypoxia
Hypovolemia
Hypo/hyperkalemia
Hypo/hyperthermia
Hydrogen ions (acidosis)

5 T's of Hypotension

Tension pneumothorax
Tamponade
Thrombosis (MI)
Thromboembolism (PE)
Toxins or tablets (drug overdose)

Most common primary diagnosis in US

Hypertension

HTN emergency

Acute and rapidly evolving end-organ damage
SBP > 220, DBP > 120
Treatment - inpatient with IV meds

HTN urgency

NO evolving end organ damage
SBP > 220, DBP > 120
Treatment - outpatient with oral meds

Non-black treatment of HTN

Start with thiazide diuretic, CCB, ACEi, or ArB

Black treatment of HTN

Start with thiazide diuretic or CCB

Kidney disease + HTN treatment

initial or add-on an ACEi or ARB

When to refer for HTN

After 3 agents used

HCTZ Caution

Avoid in patients with sulfa allergy
Can cause electrolyte issues

ACEi Caution

Pregnancy category D
- caution in renal disease - hyperkalemia
- allergic reaction = dry cough

Treatment for Tamponade

Pericardiocentesis

JVD- Kussmaul's sign

Rise in JVD with inspiration (Tamponade)

Symptoms of Restrictive Cardiomyopathy

SEVERELY ENLARGED ATRIA
- elevated JVD

Pericardial Effusion d/t CHF

Transudative effusion

Pericardial Effusion d/t Infection/Inflammation

Exudative effusion

Acute Pericarditis

T = trauma/tumor
U = uremia
M = MI
O = other infection (VIRAL, bacterial, fungal)
R = Rheumatoid, radiation
- ST elevation across all leads

Treatment for Acute Pericarditis

Colchicine*
Supportive care - NSAIDs, Aspirin
Tend to avoid corticosteroids (viral shedding)

Dressler Syndrome

#NAME?

Treatment of Constrictive Pericarditis

Pericardial Stripping

Amyloidosis

#NAME?

Leading cause of sudden cardiac death in competitive athletes

Hypertrophic Cardiomyopathy

Venturi effect

#NAME?

Brockenbrough response

#NAME?

Testing for Dilated Cardiomyopathy

Cath

Most Common Cause of Myocarditis

Coxsackievirus

Lyme Carditis

#NAME?

Acute Bacterial Endocarditis

Staph Aureus, IV drug user, Tricuspid valve, right side of heart

Subacute Bacterial Endocarditis

Strep Viridans, aortic valve, left side of heart, dental procedure prophylaxis

Janeway Lesions

Nonpainful
Erythematous
Nodular lesions on palms and soles
Associated with Bacterial Endocarditis

Osler Nodes

Painful
Red lesions on hands and feet
Associated with Bacterial Endocarditis

Roth Spots

Retinal hemorrhage with pale center
Associated with Bacterial Endocarditis

Duke Criteria

Diagnosis of Bacterial Endocarditis
- 2 major, 1 major and 3 minor, or 5 minor
- Major = 2 separate positive blood cultures (staph aureus, strep viridans, enterococcus)
- Minor = Fever, immunologic phenomena (roth spots, osler nodes, rheumatoid factors...), predisposition (IV drug use), Microbiologic evidence (positive blood culture not meeting major criteria), and vascular phenomena (arterial embolism, janeway lesions, etc)

HUTT

Head upright table tilt test
- Test for syncope

Most feared consequence of AFib

Thromboembolism --> CVA

Most common arrhythmia requiring treatment

Atrial Fibrillation

Brugada Syndrome

#NAME?

First-line treatment PVC

Beta Blockers

Causes of Junctional Rhythm

Athletes = high vagal tone
Medication = BB, CCB, antiarrhythmics, digoxin toxicity
Sick sinus syndrome = sinus node disease of "block" between SA node and AV node

Wolff-Parkinson White

- Second most common form of Supraventricular tachycardia
- Narrow to slightly widened QRS tachycardia
- Rate = 160-240 bpm
- Short PR < 0.12 msec
- Delta wave
- Treatment = Catheter based intervention preferred (avoid Cardizem)

Most Common Indication for Pacemaker

Sick Sinus Syndrome

Prinzmetal's Angina

#NAME?

Syndrome X

#NAME?

Cocaine Ischemia

AVOID BETA BLOCKERS
Treatment = Benzodiazepines, nitrates, CCB

Vulnerable plaque

#NAME?

Spontaneous Coronary Dissection

- Women > men
- 70% under age 50
- Hormonal changes, pregnancy, etc...
- Sudden split or tear between layers of coronary arteries
- Presents as ACS (acute MI), sudden cardiac death, diagnosed post mortem

Sustained Ventricular Tachycardia Treatment

Amiodarone

Framingham Point Scores

- Coronary Artery Disease
- High score = higher 10 year risk of MI
- Older, high cholesterol, smoker, low HDL, High systolic BP

Characteristics of CHF

Dyspnea and fatigue

Most common cause of Right heart failure

Left heart failure