Forensic Toxicology

toxicology

the study of drugs and poisons, and their interactions with or effects on the body

drug

a natural or synthetic substance that is used to produce physiological or psychological effects

forensic toxicology

application of toxicology in the law

40

approximately ___% of traffic deaths in the US are alcohol related

metabolism

the body's ability to break down chemicals

3 steps to metabolism

1) absorption
2) distribution
3) elimination

breath testing

the most widespread method for testing intoxication; it requires no less than 1.1 to 1.5 liters of breath to ensure that "deep-lung" breath is measured

blood analysis

calculated with a high degree of accuracy by use of gas chromatography which separates alcohol from any other chemicals

toxicologist

studies body fluid, tissue, and organs for drugs and/or poisons; may conduct postmortem pathological examinations, and examination of personal effects and empty containers, etc.; may have extremely minute quantities to test; must detect, identify, quantif

gas chromatography

separates out molecules that move up a thin coated plate; has a moving liquid and moving gas phase; the distance each component travels is based on the characteristics of that substance; compared to known samples

confirmation test

gas chromatography is completed first; then each separated component enters the mass spectrometer where the sample is broken into fragments for identification

1-3

drugs remain in the bloodstream for _____ days

7

drugs usually remain in the urine for up to _____ days

hair

drugs can remain permanently in _____ protein

behavior

once the drug is identified, the toxicologist must assess its influence on the _____ of the individual