Chapter 3

Define interstitial fluid, indicating if it is inside or outside cells (intracellular or extracellular).

Interstitial fluid is extracellular fluid outside the circulatory system and the cells.

What is the name of the hollow interior of an organ?

Lumen

Which two fluid compartments make up the extracellular fluid?

Plasma and interstitial fluid

Cell membranes are mainly constructed from ________

lipids and proteins

**Cells may store carbohydrates in the form of these cellular inclusions:

glycogen granules.

**What is the function of cilia in human cells?

Cilia beat rhythmically to move substances across the surface of the ciliated cells.

**The inclusions that destroy protein are called

proteasomes.

Tay-Sachs disease, which results from accumulation of glycolipids that are normally broken down, is associated with malfunction of which cellular component(s)?

Lysosomes

Of the protein synthesis events shown below, which occurs earliest in the process?

Ribosomes attach to the endoplasmic reticulum.

**What is the importance of having routine pap tests?

to screen for potentially cancerous cells

**Which of the following statements best describes cancer?

It is a rapid division and growth of cells that do not differentiate into specialized cells.

**Megan goes in to see her oncologist (a doctor that specializes in cancer). He tells her that the cancer is no longer isolated to her ovaries but has moved to her lungs, digestive organs, and lymph nodes. What is this condition defined as?

metastasis

**If you are a cytologist screening for cancerous cells in a pap smear sample, what would you be looking for?

large cells with big nuclei and a small amount of cytoplasm

**Upon looking at a tissue sample, you see all the signs indicative of epithelial cell dysplasia. Can you conclude with certainty that the sample is cancerous?

No, trauma as well as HPV infection can cause cellular abnormalities, which are not necessarily cancerous.

Which tissues would likely have cells with the greatest number of gap junctions?

Cardiac muscle

Which tissue can generate electrical signals?

Smooth muscle

Undifferentiated cells in a tissue that can become specialized cells of that tissue, but not of other tissues, are ________ cells.

multipotent

Functions of the cell membrane include physical isolation of the cell from its surroundings, regulation of exchange, structural support, and which other function?

Communication between the cell and its environment

The space that is surrounded by the tissue wall of hollow organs is known as

the lumen.

The lumen of a hollow organ such as the stomach is considered to be part of the ________ environment.

external

When cancer develops in one tissue and spreads to another via the blood or the lymph, the cancer is said to have undergone what process?

metastasis

The watery medium that surrounds a cell is known as

extracellular fluid

Which of the following terms is NOT used to define the structure that separates the contents of a human cell from its surrounding medium?

a cell wall

Which of the following is NOT a function of membrane proteins?
act as transport molecules for various solutes
produce energy
bind to ligands
anchor or stabilize the cell membrane
regulate the passage of ions

produce energy

Cell membranes are said to be

selectively permeable.

What is/are the major role(s) of the phospholipid bilayer?

the formation of a barrier that is selectively permeable to lipid-soluble molecules and to provide a framework for membrane proteins

Which of the following is NOT a membrane lipid?
sphingolipids
phospholipids
cholesterol
All are membrane lipids.

All are membrane lipids.

Which cellular organelle is a lipid bilayer that controls which objects can leave or enter the cell?

plasma membrane

Cell membranes are said to be ________ because they allow some substances to pass but not others.

selectively permeable

The nucleus is surrounded by a

nuclear envelope.

Communication between the nucleus and cytosol occurs through

nuclear pores

________ proteins extend all the way across the cell membrane

Integral

________ proteins attach loosely to other membrane proteins or polar regions of phospholipids.

Peripheral

A liposome is

an additive to creams and lotions and a drug-delivery vehicle.

Intermediate filaments
form the neurofilaments in nerve cells.
provide the cell with strength.
stabilize the position of organelles.
transport materials within the cytoplasm.
All of the answers are correct.

All of the answers are correct.

The cellular organelle(s) responsible for packaging and transporting proteins is/are the

Golgi complex

An immunoliposome is a liposome that

can recognize cancer cells.

Each of the following is an example of a nonmembranous organelle except one. Identify the exception.

lysosome

The thickest protein fibers from the following group are

microtubules.

Ribosomal RNA is formed by

nucleoli.

Each of the following statements concerning mitochondria is TRUE except one. Identify the exception.

The mitochondria contain no DNA or RNA.

In humans, only ________ cells have flagella.

sperm

Tay-Sachs is a disease caused by having ineffective

lysosomes

Microvilli are found

in cells that are actively engaged in absorption.

Microtubules

All of the answers are correct.

Centrioles

direct the movement of DNA during cell division.

Most of the ATP required to power cellular operations is produced in the

mitochondria.

Which does NOT accurately complete the sentence? One of the major functions of both types of endoplasmic reticulum (ER) is the

storage of genetic material for the cell.

All of the following are synthesized along various sites of the endoplasmic reticulum except one. Identify the exception.

RNA

Which of the following is NOT a molecule synthesized in the smooth endoplasmic reticulum (SER)?

proteins

Which of the following consists of a network of intracellular membranes with attached ribosomes?

rough endoplasmic reticulum

All of the structures listed below are involved in storage, EXCEPT
secretory vesicles.
lysosomes.
peroxisomes.
storage vesicles.
All are involved in cellular storage.

All are involved in cellular storage.

The proteins synthesized in the rough endoplasmic reticulum are then sent to

the Golgi complex for packaging.

If a cell lacked lysosomes, it would not be able to

digest cellular wastes and bacteria.

Which substance is responsible for activating the digestive enzymes inside lysosomes?

acid

The control center for cellular operations is the

nucleus.

The nucleus stores all the information needed to synthesize which of the following molecules?
proteins
carbohydrates
phospholipids
lipids
All of the answers are correct.

All of the answers are correct.

The term secretion refers to

the process by which a cell releases a substance into the extracellular space for a particular use.

Which cellular organelle is considered the powerhouse of the cell?

mitochondria

Movement of material between cells is known as the ________ pathway.

paracellular

Functions of epithelia include all of the following EXCEPT

storing energy reserves.

Epithelial cells that are adapted for membrane transport of materials, such as ions and nutrients, usually have ________ on their apical surface.

microvilli

The term meaning programmed cell death is

apoptosis

Groups of tissues that carry out related functions may form structures known as

organs.

All but one of the structures listed below are a type of cell junction. Identify the exception.

loose junctions

The esophagus is a tube that carries food from the mouth to the stomach. It does not secrete any enzymes or absorb any nutrients, but it does need to stand up to significant friction and stress. The type of epithelium most likely lining the esophagus woul

stratified squamous epithelium.

The type of protein found in gap junctions is the

connexin.

Disappearance of which type of junction most likely contributes to the metastasis of cancer cells throughout the body?

anchoring

The types of junction proteins important in growth and development are

CAMs.

Each of the following is a primary tissue type except one. Identify the exception.

osseous tissue

The term meaning a mitotic population of cells that persists into adulthood applies to

stem cells

Match the type of cell junction with the best description.
A. gap junction
B. tight junction
C. anchoring junction
their loss is characteristic of cancer

anchoring junction

If an animal cell lacked centrioles, it would not be able to

undergo nuclear division

Neurons in the CNS of the adult don't contain centrioles. What does that tell you about CNS neurons?

They don't replicate themselves.

The heaviest organ in the body is the

skin