Physiology Ch. 1 - Introduction to Physiology

Physiology

- The study of the function of organisms

Cells (Major Classes)

- Neurons
- Muscle Fibers
- Epithelia
- Connective Tissue Cells

Neurons

- Cells that transmit information through out the body via electrical impulses

Muscle Fibers

- Cells in the body responsible for movement through contraction

Epithelia

- Cells found in continuous sheet-like layers that form barriers

Lumen

- The interior cavity of a hollow organ

Glands

- A structure formed from epithelial cells that function in synthesis and secretion

Exocrine Gland

- A gland that secretes into a duct that leads to the external environment

Endocrine Gland

- A gland that secretes hormones into the blood stream

Hormones

- Chemical messengers secreted from endocrine glands

Connective Tissue Cells

- The most diverse of the major cell types, they are characterized by relatively disperse cells surrounded by extensive ground substance

Tissue

- A collection of similarly functioning cells

Organs

- Structures consisting of two or more tissues, combining to perform a particular function

Organ System

- The organization of different organs that work together to perform a specific function of the body

Endocrine System

- Provides communication between cells via hormones
- Hypothalamus, Pituitary, Adrenal, Thyroid, Parathyroid, Thymus, Pancreas

Nervous System

- Provides communication between cells via electrical signals and neurotransmitters
- Brain, Spinal Cord, Peripheral Nerves

Musculoskeletal System

- Supports the body; allows voluntary movement
- Skeletal muscles, Bones, Tendons, Ligaments

Cardiovascular System

- Transports molecules throughout the body in the bloodstream
- Heart, Blood vessels, Blood

Respiratory System

- Brings oxygen into the body and eliminates Carbon Dioxide
- Lungs, Pharynx, Trachea, Bronchi

Urinary System

- Filters blood to regulate acidity, volume, and ion concentration; removes waste
- Kidneys, Ureters, Bladder, Urethra

Gastrointestinal System

- Breaks down food and absorbs it
- Mouth, Esophagus, Stomach, Small intestine, Large intestine, Liver, Pancreas, Gallbladder

Reproductive System

- Generates Offspring
- Gonads, Reproductive tracts and glands

Immune System

- Defends the body against pathogens and abnormal cells
- White blood cells, Thymus, Lymph nodes, Spleen, Tonsils, Adenoids

Integumentary System

- Protects the body from external environment
- Skin

Total Body Water

- The total volume of water in the body, ~42L for 70kg person

Intracellular Fluid

- The fluid found within cells

Extracellular Fluid

- The fluid found between cells

Homeostasis

- The process of maintaining conditions in the body within a range viable for life

Negative Feedback

- The process whereby a signal causes the gradual change of a process back to normal levels

Integrating Center

- The area in the body, usually located in the brain, that receives sensory input and sends the appropriate response

Effectors

- The cells or tissue that upon receiving an output signal, bring about the appropriate response

Positive Feedback

- The process whereby a signal causes the exponential change of a process away from normal levels

Diabetes Mellitus

- Divided into type I and II, this disease centers around either the inability to produce insulin, or the for cells to be sufficiently affected by insulin, leading to increased blood glucose levels

Gestational Diabetes

- A form of type II diabetes mellitus which develops in pregnant women, only a small percentage of which are permanent

Diabetes Insipidus

- Resulting from either insufficient ADH secretion, or the inability of ADH to affect the appropriate cells in the kidney, this disease is characterized by low plasma volume and excessive urination

External Envirnment

- The area opposite the inside of the body, separated by a layer of epithelial tissue

Inspiration

- The air entering the lungs when breathing in

Expiration

- The air leaving the lungs when breathing out

Absorption

- Movement of a substance from the external environment to the internal environment by transport across an epithelium

Secretion

- Movement of substance from the internal environment to the external environment by transport across an epithelium

Excretion

- Elimination from the body through the kidneys or GI tract

Filtration

- The movement of fluid across capillary walls from plasma to the interstitium

Reabsorption

- Transport of a substance into blood

Permeable

- The characteristic of allowing a substance to pass across a membrane

Selectively Permeable

- Permeable to a specific substance

Semipermeable

- Permeable to some substances, not all

Internal Environment

- The area of the body containing all fluid compartments, separated from the external environment by a layer of epithelium

Plasma

- The extracellular fluid compartment that is the fluid portion of blood making up about 3L of the bodies total 42L of fluid

Interstitial Fluid

- The extracellular fluid compartment that is composed of fluid that bathes most cells in the body
- Similar in composition to plasma except with lesser amount of proteins

Fluid Compartments

- The different fluids of the body

Set Point

- The homeostatic value that is optimal of some variable in the body

Error Signal

- This is any difference in the actual value and set point for a homeostatic variable in the body

Chemoreceptors

- Cells that are sensitive to concentrations of oxygen and carbon dioxide in the blood

Thrmoreceptors

- Cells that are sensitive to temperature in the body

Luteinizing Hormone

- This hormone, subject to positive feedback signals, is both sensitive to and signal the release of estrogen

Estrogens

- This hormone, is triggers the positive feedback loop observed with luteinizing hormone