Ch 5 Membrane Dynamics

Body fluid compartment contains high levels of K+, large anions, and proteins?

Intracellular fluid only

Which body fluid compartment contains higher levels of Na+, Cl-, and HCO3-?

Both plasma and interstitial fluid

All of the following are types of mediated transport except one. Identify the exception
Facilitated diffusion
Primary active transport
Simple diffusion
Secondary active transport

Simple diffusion

Bulk flow is fluid flow as a result of a ___ gradient.

Pressure

Water is a polar molecule, yet it easily moves through the nonpolar portions of cell membranes. Which trasport process is responsible?

Simple diffusion

Permeability is a property of

Membranes

The term cellular (metabolic) energy indicates any biological process requiring

ATP

What are the two extracellular fluid compartments in the body?

Plasma and interstitial

Saturation occurs when

A group of carrier proteins is operating at its maximum rate

The means by which a cell trasports large molecules out of the cell is called

Exocytosis

Which of the following is a way for solutes in an aqueous solution to move from an area of high solute concentration to an area of low solute concentration?

Only facilitated diffusion

In an epithelium, the apical membrane is also known as the ___ membrane

Mucosal

Have lower concentrations of solutes than hyperosmotic solutions

Hyposmotic solutions

Which of the following statements about the resting membrane potential is true?

It results, in part, from the concentration gradients for Na+ and K+

Voltage-gated (voltage-dependant) channels and antiport carriers are both types of

Transporters

The resting membrane potential in a typical nerve cell is approximately

-70mV

Compared to the outside surface, the inside of a resting cell membrane is

Negatively charged

Caveolae and clathrin-coated pits are both used in

Endocytosis

As the charge on the membrane of a typical neuron approaches 0 from -70 mV, the cell is

Only depolarizing

The ion that plays a key role in initiating electrical signals in neurons is

Na+

Which of the following is NOT involved in creating the resting potential of a neuron?
Diffusion of potassium ions out of the cell
Diffusion of sodium ions into the cell
Resting membrane permeability for sodium ions greater than potassium ions
Resting memb

Resting membrane permeability for sodium ions greater than potassium ions

Passive transport refers to a process that requires

No cellular energy

Which of the following is NOT true of diffusion in the human body?

Smaller molecules take longer to diffuse than larger ones

Gated channels for sodium ions may include:
Mechanical gates, which respond to pressure
Chemical gates, which respond to ligands
Voltage gates, which respond to electrical signals
All
None

All of the answers are correct

When a neuron changes its ion permeability from the resting state,

Only a variety of gated ion channels may open or close and Na+ channels may open allowing Na+ to enter the cell

Transfer signals from the extracellular environment to the cytoplasm of the cell

Receptors

Form cell to cell connections

Structural proteins

Bind to molecules to facilitate entry to or exit from the cell

Transporters

Ligands bind to these proteins and are changed by the protein

Enzymes

The movement of molecules from an area of high concentration to an area of low concentration

Passive transport

The movement of molecules via proteins embedded in the cell membrane; requires ATP

Active transport

The movement of molecules against the concentration gradient

Active transport

Tends to create an equilibrium state

Passive transport

The movement of molecules from an area of high concentration to an area of low concentration

Both- simple and facilitated diffusion

The use of ATP to move molecules

Neith simple nor facilitated diffusion

A form of mediated transport

Facilitated diffusion

Conforms to the properties of specificity, competition, and saturation

Facilitated diffusion

Between adjacent cells

Paracellular tansport

From an organ's lumen to the extracellular fluid

Absorption

In one side of a cell and out the other

Transcellular transport

Movement from the extracellular fluid into the lumen of an organ

Secretion

Na+ enters the cell

Depolarization

K+ leaves the cell

More than one answer

Cl- enters the cell

Hyperpolarization

Membrane potential is 0 mV

Depolarization

This type of membrane protein extends all the way through the cell membrane into both the extra and intracellular fluid

Membrane spanning

The membrane proteins that catalyze reactions that take place on the external or internal surface of the cell are

Enzymes

The membrane proteins that bind to a ligand and cat in the bodys chemical signaling system are

Receptors

The membrane proteins that provide for support of the cell membrane and allow for cells to connect to each other are

Structural proteins

The membrane proteins that change shape and bind with specific molecules to transport them across the cell membrane are

Carrier proteins

Carrier proteins operating at their maximum rate are said to be

Saturated

The three types of gated channels are ___, ___, and ___

Chemical, voltage, and mechanical

Membrane protein pores that can be opened and closed are called __ channels

Gated

A pump that helps maintain an electrical gradient, such as the Na+ -K+ -ATPase is an ___ pump

Electrogenic

Channel proteins that allow water to pass are called

Aquaporins

Membrane protein pores that are essentially always open are called ___ or __ channels

Open, leak

A unique characteristic of glucose as a solute in biological systems?

100% of it is absorbed into the cell from the extracellular fluid

The two extracellular compartments in the body are __ and __

Plasma, interstitial fluid

The walls of the ___ separate the two extracellular fluid compartments

Circulatroy system

The ability of a carrier molecule to trasport onely one specific molecule or a group of closely related molecules is

Specificity

At rest, nerve cells have an unequal distribution of ions on either side of the cell membrane, producing the

Resting membrane potential

At rest, nerve cells have a voltage of __ mV

-70

A cell membrane that is selectively permeable

Can change which substances pass through by changing its lipid and protein content

Fick's law of diffusion states that the rate of diffusion across a membrane is

Proportional to concentration gradient, surface area, and membrane permeability

Would increase the rate of diffusion across a cell membrane

A decrease of membrane thickness

Pinocytosis and potocytosis are types of

Endocytosis

Sodium ions are more concentrated in the extracellular fluid than in the intracellular fluid. This is an example of

Chemical disequilibrium

Which property of diffusion best helps explain the necessity of the circulatory system in multicellular organisms?

Diffusion is rapid over short distances but much slower over long distances

Facilitated diffusion and active transport differ in that

ATP is necessary for active transport, but not for facilitated diffusion

Water will always move from ___ areas to ___ areas, if there are no impermeable barriers.

Hyposmotic, hyperosmotic

Substances that readily dissolve in water and do not readily dissolve in lipids are

Hydrophlic and lipophobic

Which can move across the phospholipid bilayer by simple diffusion?

ALL lipids, steroids, water

Cations will __ each other

repel

Anions will ___ each other

repel

The cell membrane acts as a good

Electrical insulator

Resting membrane potential of -70 mV to +30 mV

Depolarization

From -50 mV to resting membrane potential of -70 mV

Repolarization

From -90 mV to resting membrane potential of -70 mV

Repolarization

The concentration of calcium inside a cell is 0.3%. The concentration of calcium outside the cell is 0.1%. How could the cell transport even more calcium to the inside?

Active Transport

Which body fluid compartment contains high levels of K+, large anions, and proteins?

Intracellular fluid only

Which of the following is a unique characteristic of glucose as a solute in biological systems?

100% of it is absorbed into the cell from the extracellular fluid.

Which of the following statements about the Na+/K+ pump is FALSE?
Its activity requires the expenditure of metabolic (cellular) energy.
It transports Na+ and K+ in a 1:1 ratio.
It transports Na+ out of the cell and K+ into the cell.
It is present in neuro

It transports Na+ and K+ in a 1:1 ratio

What is a nonpenetrating (NP) solute?

A solute that will not cross the cell membrane.

Membrane receptors are involved in various types of cell signaling. Some membrane receptors function as _____ channels.

Chemically gated

Cell membranes are primarily made of _____ molecules.

Phospholipids