acromegaly
enlargement of bones of hands and feet and face
Addison's disease
rare childhood disorder with deficiencies of glucocorticoids and mineralocorticoids, may occur as a result of trauma, infection or autoimmune response, develops gradually.
cretinism
condition of congenital hypothyroidism in children that results in a lack of mental development and dwarfed physical stature; the thyroid gland is either congenitally absent or imperfectly developed
Crushing's syndrome
Aldosterone and Cortisol
(oversecretion)
high blood glucose and blood pressure altered protein and carbohydrate metabolism
goiter
enlargement of the thyroid gland caused by thyroid dysfunction, tumor, lack of iodine in the diet, or inflammation (goiter = throat)
Graves' disease
Multisystem autoimmune disorder characterized by pronounced hyperthyroidism usually associated with enlarged thyroid gland and exophthalmos (abnormal protrusion of the eyeball)
hyperthyroidism
an overactive thyroid gland
myxedema
advanced hypothyroidism in adults characterized by sluggishness, slow pulse, puffiness in the hands and face, and dry skin (myx = mucous)
polyuria
renal disorder characterized by the production of large volumes of pale dilute urine
Waterhouse-Friderichsen Syndrome
This is a disease of the adrenal glands most commonly caused by the bacterium Neisseria meningitidis. The infection leads to massive hemorrhage into one or (usually) both adrenal glands. It is characterized by overwhelming bacterial infection meningococce
Diabetes Mellitus
diabetes caused by a relative or absolute deficiency of insulin and characterized by polyuria
Pancreas Cancer
RF- smoking, alcohol, AA descent, 60-80 yrs old, high fat diet, DM. S&S- insidious onset, pain (dull epigastric to back), jaundice, wt loss, intestinal obstruction, N/V. Rx- remove pancreas, 99% mortality, pain control, chemo & radiation is inclusive
Giantism
from childhood persons size is pathologically large but person will be weak, not a proportionate growth of contractile proteins in mucles, prone to diabetes, die early
Dwarfism
Deficiency of the GH results in _____ which becomes apparent by 6 months of age, infant exhibits growth retardation, chubbiness in lower trunk & short stature. Secondary tooth eruption delayed & delay in puberty. Sex hormones may not develop normally unle
Diabetes Insipidus
a rare form of diabetes resulting from a deficiency of vasopressin (the pituitary hormone that regulates the kidneys)
Hyperparathyroidism
excessive secretion of parathyroid hormone resulting in abnormally high levels of calcium in the blood
Hypoparathyroidism
inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood
Hypothyroidism
condition of hyposecretion of the thyroid gland causing low thyroid levels in the blood that result in sluggishness, slow pulse, and often obesity
Acetone
Ketone body produced in abnormal amounts in uncontrolled diabetes mellitus, when there is excessive fat breakdown in cells.
Type I Diabetes
pancreatic cells Insulin is not produced by the pancreas, impacting glucose utilization and insulin-dependant functions. Increase in adipose lipase, Acetyl-CoA carboxylase falls (not making F.A.s). Untreated diabetics produce excessive ketone bodies and t
Type II Diabetes
mild form of diabetes mellitus that develops gradually in adults
Adenoma
a benign tumor of a gland can stimulate over secretion of hormone in the structure from which it develops
Exophthalmia
protrusion of the eyeball from its orbit; may be congenital or the result of an endocrine disorder
Primary dilution
Occurs when the concentrated fluid is mixed with water in the tank of the embalming machine. It is controlled by the embalmer
Secondary dilution
Occurs when the injected arterial fluid mixes with the fluids in the deceased's remains. It is not under the embalmer's direct control. It may be necessary, therefore, to utilize several injection points with different strengths and quantities of embalmin