83. All of the following are true of patients with cystic fibrosis EXCEPT:
a. may have meconium ileus
b. recurrent pulmonary infections are responsible for death in majority of patients
c. atrophy and fibrosis of pancreas
d. etiology is an enzyme defect
e
D
90. All of the following are true of idiopathic respiratory distress syndrome of the newborn EXCEPT:
a. associated with prematurity
b. characterized by patchy areas of atelectasis alternating with hyperaerated areas of lung parenchyma
c. fundamental defec
B
101. All of the following are true of acute bronchopneumonia EXCEPT:
a. represents patchy areas of consolidation of lung parenchyma usually bilateral and centered around bronchi and bronchioles
b. necrotizing bronchopneumonias with abscess formation may b
C
104. All of the following are true of sarcoidosis EXCEPT:
a. basic lesion is non-caseating granuloma
b. Stage IV sarcoidosis shows extensive parenchymal involvement often with fibrosis
c. diagnosis is established by the demonstration of a high serum angio
C
107. All of the following are true of Coal Worker's pneumoconiosis EXCEPT:
a. patients have increased incidence of gastric carcinoma
b. disease progresses in spite of eliminating patient's exposure to coal dust
c. progressive disease results in large pulm
B
110. Which of the following pneumoconiosis are implicated in the development of tuberculosis?
a. asbestosis
b. silicosis
c. Black lung disease
d. a and b
e. b and c
B
120. The Ghon focus refers to:
a. subpleural granuloma in sarcoidosis
b. subpleural granuloma plus granulomas in ipsilateral hilar lymph nodes in tuberculosis
c. subpleural granuloma in tuberculosis
d. subpleural granuloma plus granuloma in ipsilateral hi
C
132. All of the following are true of asbestosis EXCEPT:
a. uncoated fibers predominate over ferruginous bodies and are difficult to identify with the light microscope
b. progressive disease may result in significant pulmonary fibrosis
c. associated with
C
133. The most common histologic subtype of carcinoma of the lung is:
a. large cell undifferentiated carcinoma
b. small cell carcinoma
c. bronchogenic adenocarcinoma
d. squamous cell carcinoma
e. combined adenosquamous carcinoma
D
138. The malignant tumor of the lungs which arises in area of a previous scar is MOST frequently which histologic subtype:
a. carcinoid
b. broncho-alveolar carcinoma
c. squamous cell carcinoma
d. adenocarcinoma
e. small cell carcinoma
D
139. Which of the following features characterize panlobular emphysema?
a. punched out holes often with deposits of black pigment
b. usually involves the apices of the lungs
c. destruction of respiratory bronchioles, alveolar ducts and sacs
d. associated
C
140. Which of the following is NOT associated with cigarette smoking?
a. chronic bronchitis
b. squamous cell carcinoma of the lung
c. squamous metaplasia of bronchial epithelium
d. oat cell carcinoma of the lung
e. they are all associated with cigarette s
E
142. All of the following are true of patients with primary tuberculosis EXCEPT:
a. apices of the lung are primarily involved
b. granulomatous inflammation may extend to the hilar lymph nodes producing a Ghon complex
c. elicits a type IV hypersensitivity
A
143. Chronic obstructive pulmonary disease includes all of the following EXCEPT:
a. bronchial asthma
b. bronchiectasis
c. sarcoidosis
d. emphysema
e. chronic bronchitis
C
144. All of the following are true of centrilobular emphysema EXCEPT:
a. cystic spaces can be seen grossly within the center of secondary lobules
b. apices of the lung are more commonly involved than lower lobes
c. due to marked reduction of alpha-1 antit
C
145. Your patient presents with complaints of respiratory difficulty for many years. He is a heavy smoker with a productive cough and purulent, foul-smelling sputum. He states that in the morning before getting out of bed he has to "clear his lung" by lyi
C
202. Cystic fibrosis (mucoviscidosis) is best diagnosed clinically by:
a. a roentgenogram of the chest
b. determination of lipase levels in the stool
c. biopsy of the pancreas
d. measurement of the electrolytes in sweat
e. biopsy of the small intestine
D
214. Bronchogenic carcinoma tend to metastasize mainly:
a. by local invasion only
b. via the lymphatics
c. by hematogenous routes
d. by bronchial dissemination
e. within the thorax only
B
220. The worst prognosis is found in which tumor of the lung?
a. Squamous cell carcinoma
b. Small cell (oat cell) carcinoma
c. Lymphosarcoma
d. Adenocarcinoma
e. Bronchiolar-alveolar carcinoma
B
221. Aspiration of foreign material more easily involves which lobe?
a. Right lower lobe
b. Right upper lobe
c. Left lower lobe
d. Left upper lobe
e. Right middle lobe
E
225. Pulmonary hyaline membrane may be found in:
a. patients dying of acute viral pneumonia
b. adults dying of uremia
c. patients dying of severe bacterial infection
d. patients dying of "shock" lung
e. all of the above
E
152. All of the following play a role in the development of neonatal respiratory distress syndrome EXCEPT:
a. Acidosis
b. Atelectasis
c. Decreased alveolar surfactant
d. Hyaline membranes
e. Pulmonary vasodilation
E
153. All of the following are examples of processes that diffusely involve the lung airspaces EXCEPT:
a. Eosinophilic pneumonia
b. Pneumocystis jiroveci pneumonia
c. Pulmonary alveolar proteinosis
d. Pulmonary hemorrhage
e. Sarcoidosis
E
154. Which form of lung injury is similar to diffuse alveolar damage, is localized to the peribronchiolar parenchyma, and is characterized by fibroblastic plugs?
a. Acute interstitial pneumonia
b. Brochiolitis obliterans-organizing pneumonia
c. Lymphocyti
B
155. Coating with which of the following particles leads to formation of an asbestos body?
a. Cadmium
b. Calcium
c. Copper
d. Iron
e. Lead
D
156. The pathologic triad of temporally uniform chronic interstitial pneumonia with peribronchiolar accentuation, non-necrotizing granulomas in peribronchiolar interstitium, and foci of bronchiolitis obliterans is diagnostic of which of the following path
B
157. A 25 year old man presents with acute onset hemoptysis, anemia, azotemia, and diffuse pulmonary infiltrates. A kidney biopsy shows membranoproliferative glomerulonephritis with linear IgG deposits. What is the MOST likely cause of this patient's symp
C
159. Which of the MOST common organism isolated from cystic fibrosis patients presenting with recurrent pulmonary infections?
a. Chlamydia pneumoniae
b. Haemophilus influenza
c. Mycoplasma pneumoniae
d. Pseudomonas aeruginosa
e. Streptococcus pneumoniae
D
160. A 65 year old man with a significant smoking history is found to have an exophytic, cavitary mass obstructing the main bronchus. Based on this information, what is the MOST likely diagnosis?
a. Adenocarcinoma
b. Carcinoid tumor
c. Large cell carcinom
E
161. Centrilobular emphysema is MOST closely associated with which of the following etiologies?
a. Alpha-1 antitrypsin deficiency
b. Aspiration
c. Focal lesions
d. Large scars
e. Long standing tobacco use
E