The fluoroquinolones exhibit what type of activity against S. pneumoniae
Concentration dependent bacteriostatic activity
Concentration dependent bactericidal activity
Which of the following best describes the mechanism of action of sulfonamides?
Inhibiting folate synthesis
The decision-making process where a clinician chooses an agent based on patient characteristics and site of infection is call:
Empiric therapy
What describes the mechanism of action of the macrolides?
Inhibition of bacterial protein biosynthesis
Which of the following characteristics apply to the macrolides?
Effective against atypical pathogens
Which of the following best describes the mechanism of action of beta-lactams?
Disrupt synthesis of peptidoglycan layer of bacterial cell walls
An antibiotic described as having bacteriostatic action is capable of:
Inhibiting growth or reproduction of an organism
The use of which of the following agents should be avoided in children and pregnant women due to the possibility of teeth staining?
Doxycycline
The lowest concentration of an antimicrobial that will prevent growth of 99.9% of an organism after subculture onto antibiotic-free media is:
Minimum bactericidal concentration
H. Influenzae's primary mechanism of antimicrobial resistance is via
Beta-lactamase production
A 26 year old woman presents with uncomplicated UTI. She is otherwise healthy, has not received any system antimicrobials in the past year], does not have a sulfa allergy, and is not taking any medications other than Ortho-Cyclen (ethinyl estradiol and no
Trimethoprim-sulfamethoxazole
A 13 year old boy presents with acute bacterial rhinosinusitis. He has a beta-lactam allergy and had taken clarithromycin 2 months ago for a bad cold. You recommend treatment with
Levofloxacin
What antimicrobials would be expected to exhibit in vitro activity against beta-lactamase producing Moraxella catarrhalis
Amoxicillin-clavulanate
Doxycycline
Moxifloxcain
All of the following antimicrobials would be expected to exhibit in vitro activity against beta-lactamase producing Moraxella catarrhalis except:
Amoxicillin
In geographic areas where E.coli resistance to TMP/SMX is >20%, alternative treatments include phenazopyridine and what else?
Ciprofloxacin
Levofloxacin
Nitrofurantoin
In geographic areas where E.coli resistance to TMP/SMX is >20%, alternative treatments include phenazopyridine plus all of the following except:
Amoxicillin
Risk factors fr developing fluoroquinolone-associated tendonitis rupture include..?
Age >60
Current systemic corticosteroid use
History of heart transplant
Risk factors fr developing fluoroquinolone-associated tendonitis rupture include all of the following except:
Recent use of a systemic beta-lactam antimicrobial
For the minority (<10%) of acute bronchitis cases not caused by a virus, the likely causative pathogens include..?
Bordetella pertussis
Chlamydophila pneumoniae
Mycoplasma pneumoniae
For the minority (<10%) of acute bronchitis cases not caused by a virus, the likely causative pathogens include all of the following except:
Haemophilus influenza
A 46-year-old man who is currently smoking 1 PPD and has a 30 pack year cigarette smoking history with a penicillin allergy presents with acute bacterial rhinosinusitis. Three weeks ago, he was treated with a macrolide for "bronchitis". You now prescribe:
Levofloxacin
The recommended regimen of fosfomycin for the treatment of uncomplicated UTI in a non-pregnant woman is:
One dose 3g
A 35 year old woman who is not pregnant was initiated on high-dose amoxicillin 4 days ago to treat acute bacterial rhinosinusitis. She returns complaining of no change in symptoms. You recommend switching her treatment to:
Levofloxacin
A 35 year old woman with a sulfa allergy presents with uncomplicated UTI. She has not received any systemic antimicrobials in more than 6 months. She is currently not pregnant and using norelgestromin/ethinyl estradiol patch (Ortho Evra). You recommend tr
Nitrofurantoin